PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei
Protein expressioni No data
RNA expressioni
Consensus:34.6 nTPM
HPA:34.6 nTPM
FANTOM5:501.7 Scaled Tags Per Million
Pig:106.8 nTPM
Mouse:101.9 nTPM
Allen mouse:3.8 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 34.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 2.2
2188 Female, age 91, both hemispheres 5.0
2301 Female, age 85, both hemispheres 2.4
2090 Male, age 80, both hemispheres 1.3
1984 Male, age 76, both hemispheres 0.0
Area postrema
nTPM: 0.0
2054 Male, age 76, both hemispheres 0.0
2306 Male, age 80, both hemispheres 0.0
2799 Male, age 61, both hemispheres 0.0
Cuneate nuclei
nTPM: 2.6
2376 Male, age 61, both hemispheres 4.9
2131 Male, age 76, both hemispheres 2.9
2381 Male, age 80, both hemispheres 0.0
Dorsal cochlear nucleus
nTPM: 2.8
2187 Female, age 91, both hemispheres 12.9
2058 Male, age 76, both hemispheres 1.2
2370 Male, age 61, both hemispheres 0.0
2378 Male, age 80, both hemispheres 0.0
2802 Male, age 74, right hemisphere 0.0
Dorsal medullary reticular nucleus
nTPM: 10.0
2040 Female, age 85, both hemispheres 30.0
2088 Male, age 76, both hemispheres 0.0
2373 Male, age 61, both hemispheres 0.0
Dorsal motor vagal complex
nTPM: 7.4
2133 Female, age 91, both hemispheres 25.8
2844 Male, age 55, unknown 17.9
2000 Male, age 74, unknown 13.1
2813 Female, age 72, unknown 2.3
2185 Male, age 76, both hemispheres 0.0
2643 Male, age 74, both hemispheres 0.0
2797 Male, age 61, both hemispheres 0.0
2807 Female, age 85, both hemispheres 0.0
Dorsal tegmental nucleus
nTPM: 3.5
2083 Male, age 80, both hemispheres 12.6
2326 Male, age 74, both hemispheres 1.6
1936 Male, age 76, left hemisphere 0.0
2358 Male, age 61, both hemispheres 0.0
Dorsolateral tegmental area
nTPM: 8.1
2751 Female, age 85, both hemispheres 16.2
2141 Male, age 76, both hemispheres 13.7
2654 Male, age 80, both hemispheres 8.8
2360 Male, age 74, both hemispheres 2.0
2337 Male, age 61, both hemispheres 0.0
Gigantocellular reticular nuclei, medullary
nTPM: 10.3
2462 Male, age 74, both hemispheres 23.6
1876 Female, age 85, both hemispheres 14.5
2314 Male, age 61, both hemispheres 7.3
2022 Male, age 76, right hemisphere 7.2
2310 Male, age 80, both hemispheres 4.8
2387 Female, age 91, both hemispheres 4.3
Gigantocellular reticular nuclei, pars
nTPM: 10.7
2168 Male, age 76, both hemispheres 24.6
2084 Female, age 85, both hemispheres 16.8
2336 Male, age 61, both hemispheres 12.5
2330 Male, age 80, both hemispheres 0.0
2706 Male, age 80, both hemispheres 0.0
Inferior olive
nTPM: 2.1
2563 Male, age 74, both hemispheres 6.7
2085 Female, age 85, both hemispheres 2.2
2178 Male, age 61, both hemispheres 1.4
2379 Male, age 80, both hemispheres 0.0
2628 Female, age 91, both hemispheres 0.0
Kolliker-Fuse nucleus
nTPM: 7.0
2163 Male, age 80, both hemispheres 13.0
2793 Female, age 91, left hemisphere 8.0
2315 Male, age 76, right hemisphere 0.0
Lateral lemniscal nuclei
nTPM: 20.3
2036 Male, age 80, both hemispheres 27.7
2453 Male, age 74, right hemisphere 24.1
2169 Male, age 76, both hemispheres 23.3
2746 Female, age 85, left hemisphere 20.8
2320 Female, age 91, left hemisphere 5.5
Lateral medullary reticular nucleus
nTPM: 9.2
2305 Male, age 74, both hemispheres 24.1
2044 Male, age 76, both hemispheres 18.6
2374 Male, age 61, both hemispheres 6.2
2190 Female, age 85, both hemispheres 3.4
2804 Female, age 91, both hemispheres 2.7
2852 Male, age 80, both hemispheres 0.0
Lateral parabrachial nucleus
nTPM: 9.4
2139 Female, age 85, right hemisphere 27.4
2013 Male, age 80, both hemispheres 5.9
2790 Male, age 61, both hemispheres 4.2
2792 Male, age 76, both hemispheres 0.0
Lateral vestibular nucleus
nTPM: 5.0
2184 Male, age 76, both hemispheres 10.0
2311 Male, age 80, both hemispheres 0.0
Locus coeruleus
nTPM: 34.6
2014 Male, age 55, unknown 49.9
2123 Female, age 91, both hemispheres 48.7
2720 Male, age 74, both hemispheres 33.0
2317 Female, age 72, unknown 31.3
2788 Male, age 74, unknown 27.5
1980 Male, age 76, both hemispheres 26.2
2162 Male, age 80, both hemispheres 25.2
Medial olivary nucleus
nTPM: 2.1
1943 Male, age 61, both hemispheres 8.4
1962 Male, age 76, both hemispheres 0.0
2138 Female, age 91, both hemispheres 0.0
2851 Male, age 80, both hemispheres 0.0
Medial parabrachial nucleus
nTPM: 8.9
2170 Female, age 91, both hemispheres 21.5
2854 Male, age 80, both hemispheres 15.2
2786 Male, age 76, both hemispheres 5.0
2463 Female, age 85, right hemisphere 2.4
2156 Male, age 61, both hemispheres 0.3
Medial periolivary nuclei
nTPM: 18.5
2171 Female, age 85, both hemispheres 41.3
2063 Male, age 76, both hemispheres 25.0
2791 Male, age 74, right hemisphere 19.6
2081 Male, age 80, both hemispheres 5.0
2458 Female, age 91, both hemispheres 1.6
Medial vestibular nucleus
nTPM: 16.2
2801 Male, age 74, both hemispheres 22.3
2134 Male, age 76, both hemispheres 19.7
2743 Female, age 85, both hemispheres 17.1
2093 Male, age 80, both hemispheres 15.7
2803 Female, age 91, both hemispheres 11.4
2624 Male, age 61, both hemispheres 10.7
Motor facial nucleus
nTPM: 15.5
2365 Male, age 74, right hemisphere 28.7
2062 Male, age 76, both hemispheres 28.0
2697 Female, age 85, both hemispheres 12.3
2327 Male, age 80, both hemispheres 11.8
2126 Male, age 61, both hemispheres 11.5
2795 Female, age 91, both hemispheres 0.8
Motor hypoglossal nucleus
nTPM: 11.1
2125 Female, age 91, both hemispheres 23.4
2132 Female, age 85, both hemispheres 21.4
2461 Male, age 61, both hemispheres 8.7
2182 Male, age 80, both hemispheres 1.3
2277 Male, age 76, both hemispheres 0.7
Motor trigeminal nucleus
nTPM: 6.0
2079 Male, age 80, both hemispheres 14.6
2560 Male, age 74, both hemispheres 9.0
2321 Female, age 91, both hemispheres 3.2
2335 Male, age 61, both hemispheres 2.6
2309 Male, age 76, both hemispheres 0.4
Nuclei of the trapezoid body
nTPM: 21.5
2159 Male, age 61, both hemispheres 41.4
2735 Female, age 85, both hemispheres 38.0
1983 Male, age 76, both hemispheres 18.1
2166 Male, age 80, both hemispheres 8.1
2368 Female, age 91, both hemispheres 2.2
Nucleus ambiguus
nTPM: 11.5
2096 Female, age 85, both hemispheres 23.0
2071 Male, age 76, both hemispheres 0.0
Nucleus cuneatus
nTPM: 0.0
2100 Male, age 76, both hemispheres 0.0
2380 Male, age 80, both hemispheres 0.0
2562 Male, age 61, both hemispheres 0.0
2564 Male, age 74, both hemispheres 0.0
2805 Female, age 91, both hemispheres 0.0
2808 Female, age 85, both hemispheres 0.0
Nucleus gracilis
nTPM: 2.5
2627 Male, age 74, both hemispheres 7.7
2299 Female, age 85, both hemispheres 0.0
2382 Male, age 80, both hemispheres 0.0
Nucleus raphe magnus
nTPM: 25.6
2160 Male, age 61, both hemispheres 58.0
2172 Female, age 85, both hemispheres 44.2
2455 Male, age 74, both hemispheres 29.8
2328 Male, age 80, both hemispheres 10.2
2051 Male, age 76, both hemispheres 7.4
2459 Female, age 91, both hemispheres 3.9
Nucleus raphe obscurus
nTPM: 8.1
2800 Male, age 61, midline 15.5
2845 Female, age 85, midline 8.8
2142 Male, age 76, midline 0.0
Nucleus raphe pallidus
nTPM: 7.0
2183 Male, age 80, midline 12.8
1924 Male, age 61, midline 8.4
2145 Male, age 76, midline 0.0
Nucleus tractus solitarii
nTPM: 3.9
2144 Female, age 91, right hemisphere 8.0
2656 Male, age 76, both hemispheres 7.6
2191 Female, age 85, both hemispheres 0.0
2307 Male, age 80, both hemispheres 0.0
Paramedian reticular nucleus
nTPM: 18.7
2050 Female, age 85, both hemispheres 35.8
2313 Male, age 61, both hemispheres 20.3
2057 Male, age 80, both hemispheres 18.3
2052 Male, age 76, both hemispheres 0.2
Parvicellular reticular nuclei
nTPM: 11.5
2558 Male, age 74, both hemispheres 14.0
2119 Male, age 80, both hemispheres 13.0
2095 Male, age 76, both hemispheres 7.6
Parvicellular reticular nuclei, medullary
nTPM: 14.5
2189 Female, age 91, both hemispheres 18.8
2091 Female, age 85, both hemispheres 14.5
2181 Male, age 80, left hemisphere 10.2
Peritrigeminal nucleus
nTPM: 13.5
2179 Male, age 61, both hemispheres 17.8
2136 Male, age 76, both hemispheres 11.5
2067 Female, age 85, both hemispheres 11.2
Pontine nuclei
nTPM: 26.5
2727 Male, age 61, right hemisphere 47.8
2787 Female, age 85, both hemispheres 45.8
1863 Male, age 55, unknown 45.5
2109 Female, age 72, unknown 31.1
2454 Male, age 74, left hemisphere 24.5
1968 Male, age 76, left hemisphere 14.2
2319 Female, age 91, both hemispheres 3.2
2115 Male, age 80, left hemisphere 0.0
Pontine raphe nucleus
nTPM: 23.5
2122 Female, age 85, midline 28.8
2853 Male, age 76, midline 18.2
Posteroventral cochlear nucleus
nTPM: 7.3
2752 Female, age 85, both hemispheres 22.1
2070 Male, age 76, both hemispheres 12.0
2135 Female, age 91, both hemispheres 2.4
2341 Male, age 80, both hemispheres 0.0
2371 Male, age 61, both hemispheres 0.0
Prepositus hypoglossal nucleus
nTPM: 9.0
2855 Female, age 85, right hemisphere 18.1
2086 Male, age 80, both hemispheres 0.0
Principal sensory trigeminal nucleus
nTPM: 20.2
2158 Male, age 61, both hemispheres 44.4
2008 Male, age 80, left hemisphere 25.0
2367 Female, age 91, left hemisphere 9.9
2324 Male, age 76, both hemispheres 1.5
Reticular pontine nucleus, caudal
nTPM: 8.6
2092 Male, age 76, both hemispheres 12.3
2332 Male, age 80, right hemisphere 12.0
2559 Male, age 74, both hemispheres 10.1
2457 Female, age 91, both hemispheres 0.0
Reticular pontine nucleus, oral
nTPM: 15.5
2012 Female, age 85, both hemispheres 27.8
2361 Male, age 74, both hemispheres 25.9
1939 Male, age 80, both hemispheres 14.5
2167 Male, age 76, both hemispheres 8.6
2366 Female, age 91, both hemispheres 0.9
Reticulotegmental nucleus
nTPM: 8.2
2325 Male, age 76, both hemispheres 18.8
2452 Male, age 74, both hemispheres 6.4
2322 Female, age 91, both hemispheres 4.7
2333 Male, age 80, both hemispheres 2.8
Spinal trigeminal nucleus, caudal
nTPM: 5.5
2390 Female, age 91, both hemispheres 25.6
2642 Male, age 74, both hemispheres 1.1
2447 Male, age 76, both hemispheres 1.0
2308 Male, age 80, both hemispheres 0.0
2312 Male, age 61, both hemispheres 0.0
Spinal trigeminal nucleus, interpolar
nTPM: 22.3
2066 Male, age 76, right hemisphere 39.8
2625 Male, age 61, both hemispheres 33.5
2033 Male, age 80, both hemispheres 16.4
2389 Female, age 91, both hemispheres 12.7
2386 Female, age 85, both hemispheres 8.9
Spinal trigeminal nucleus, oral
nTPM: 6.3
2737 Female, age 85, both hemispheres 11.1
2164 Male, age 80, both hemispheres 6.9
1978 Male, age 76, both hemispheres 1.0
Spinal vestibular nucleus
nTPM: 7.7
2186 Female, age 91, both hemispheres 16.3
2806 Female, age 85, both hemispheres 9.5
2780 Male, age 80, both hemispheres 8.3
2748 Male, age 76, both hemispheres 6.0
2384 Male, age 74, both hemispheres 3.3
2796 Male, age 61, both hemispheres 2.5
Subcoeruleus area
nTPM: 15.1
2323 Female, age 91, left hemisphere 28.4
1958 Male, age 80, both hemispheres 19.4
2089 Male, age 76, left hemisphere 13.5
2369 Female, age 85, left hemisphere 9.9
2451 Male, age 74, both hemispheres 4.1
Superior olive
nTPM: 15.0
1875 Female, age 85, both hemispheres 35.6
2364 Male, age 74, right hemisphere 16.7
2020 Male, age 76, both hemispheres 10.2
2329 Male, age 80, right hemisphere 8.5
2561 Female, age 91, both hemispheres 4.1
Superior vestibular nucleus
nTPM: 3.8
2015 Male, age 80, both hemispheres 9.1
2383 Male, age 74, both hemispheres 2.2
2061 Male, age 76, both hemispheres 0.0
Ventral medullary reticular nucleus
nTPM: 8.7
2060 Male, age 76, both hemispheres 9.7
2372 Male, age 61, both hemispheres 7.7
Ventral periolivary nuclei
nTPM: 20.3
2130 Female, age 85, both hemispheres 40.1
2165 Male, age 80, both hemispheres 21.0
2023 Male, age 76, both hemispheres 12.2
2794 Female, age 91, left hemisphere 7.9
Ventrolateral medulla, A1-C1 cell groups
nTPM: 10.2
1986 Male, age 76, both hemispheres 17.2
2741 Female, age 85, both hemispheres 17.1
2180 Male, age 61, both hemispheres 15.7
2302 Female, age 91, both hemispheres 1.0
2118 Male, age 80, both hemispheres 0.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 12.3
2449 Male, age 74, both hemispheres 22.9
2840 Female, age 85, both hemispheres 18.4
2359 Male, age 61, both hemispheres 14.9
1959 Male, age 76, both hemispheres 14.6
2161 Male, age 80, both hemispheres 3.0
2456 Female, age 91, both hemispheres 0.2

PONS AND MEDULLA - FANTOM5 CAGEi
Max Scaled Tags Per Million 501.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 227.0
FF:10182-103D2 60 years, female 247.3
FF:10165-103B3 76 years, female 206.8
Medulla oblongata
Scaled Tags Per Million: 225.8
FF:10038-101F2 18-64 years, mixed 368.7
FF:10174-103C3 60 years, female 164.9
FF:10155-103A2 76 years, female 143.9
Pons
Scaled Tags Per Million: 501.7
FF:10033-101E6 18-54 years, mixed 501.7

PONS AND MEDULLA - Pig RNA-seqi
Average nTPM 106.8
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 72.2
Samples: 4

Max nTPM: 82.8
Min nTPM: 56.5
Sample A Female 76.9
Sample B Female 72.6
Sample C Male 82.8
Sample D Male 56.5
Pons
nTPM: 106.8
Samples: 4

Max nTPM: 140.6
Min nTPM: 91.2
Sample A Female 140.6
Sample B Female 91.2
Sample C Male 104.1
Sample D Male 91.2

PONS AND MEDULLA - Mouse RNA-seqi
Average nTPM 101.9
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 102.0
Samples: 4

Max nTPM: 106.8
Min nTPM: 94.9
Sample A Male 105.0
Sample B Male 106.8
Sample C Female 101.1
Sample D Female 94.9

PONS AND MEDULLA - Allen Mouse ISHi
Max Expression energy 3.8
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 3.5
126 Antisense, RP_Baylor_102642, Mouse strain C57BL/6J (56 days, male) 6.8
127 Antisense, RP_Baylor_102642, Mouse strain C57BL/6J (56 days, male) 2.5
128 Sense, RPS_Baylor_36955, Mouse strain C57BL/6J (56 days, male) 0.1
Pons
Expression energy: 3.8
126 Antisense, RP_Baylor_102642, Mouse strain C57BL/6J (56 days, male) 7.6
127 Antisense, RP_Baylor_102642, Mouse strain C57BL/6J (56 days, male) 2.0
128 Sense, RPS_Baylor_36955, Mouse strain C57BL/6J (56 days, male) 0.0

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