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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:107.0 nTPM
HPA:107.0 nTPM
GTEx:78.1 nTPM
FANTOM5:371.2 Scaled Tags Per Million
Pig:119.2 nTPM
Mouse:235.4 nTPM
Allen mouse:17.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 107.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 82.9
2411 Female, age 72, unknown 97.5
2019 Male, age 18, unknown 91.9
1870 Female, age 42, unknown 90.8
2666 Male, age 74, left hemisphere 90.5
1827 Male, age 72, unknown 84.2
1833 Male, age 53, unknown 81.7
2828 Female, age 72, unknown 80.9
1830 Male, age 51, unknown 80.6
2219 Male, age 76, both hemispheres 67.5
2586 Male, age 75, left hemisphere 63.3
Dorsal raphe nucleus
nTPM: 93.2
2298 Female, age 72, unknown 122.3
2047 Male, age 72, unknown 90.1
1828 Male, age 53, unknown 89.7
2016 Female, age 72, unknown 82.8
2750 Male, age 76, both hemispheres 81.3
Inferior colliculus
nTPM: 86.1
2097 Female, age 72, unknown 99.6
1848 Female, age 42, unknown 83.2
1890 Male, age 53, unknown 83.2
2849 Male, age 72, unknown 78.3
Median raphe nucleus
nTPM: 104.4
2220 Male, age 76, midline 104.4
Pedunculopontine tegmental nucleus
nTPM: 95.6
2334 Male, age 80, both hemispheres 104.0
2338 Male, age 61, both hemispheres 96.2
1921 Female, age 85, both hemispheres 86.6
Periaquaductal grey, anterior
nTPM: 91.5
1947 Male, age 18, unknown 96.2
2502 Female, age 75, unknown 92.7
1795 Male, age 51, unknown 85.7
Periaquaductal grey, dorsal
nTPM: 88.3
2850 Male, age 76, both hemispheres 108.2
1840 Male, age 53, unknown 88.1
2464 Female, age 72, unknown 79.0
1831 Male, age 72, unknown 78.2
Periaquaductal grey, lateral
nTPM: 107.0
2272 Male, age 74, both hemispheres 132.7
2140 Male, age 76, both hemispheres 104.4
2053 Male, age 18, unknown 83.9
Pretectal area
nTPM: 94.5
2273 Male, age 74, both hemispheres 145.8
2224 Female, age 72, unknown 102.9
2007 Male, age 72, unknown 94.2
1944 Female, age 72, unknown 92.5
1817 Female, age 42, unknown 91.5
2667 Female, age 75, unknown 90.0
1816 Male, age 51, unknown 89.5
2407 Male, age 75, both hemispheres 86.9
1815 Male, age 53, unknown 86.7
2825 Male, age 18, unknown 85.6
2316 Male, age 76, right hemisphere 74.2
Red nucleus
nTPM: 80.0
2725 Female, age 75, unknown 93.8
1821 Female, age 72, unknown 87.7
1954 Female, age 42, unknown 87.4
2785 Male, age 18, unknown 85.7
1904 Male, age 53, unknown 83.5
2503 Female, age 72, unknown 83.1
1865 Male, age 51, unknown 82.9
2227 Male, age 72, unknown 79.3
2769 Male, age 72, unknown 78.6
2584 Male, age 75, left hemisphere 74.2
2823 Male, age 76, right hemisphere 67.1
2588 Male, age 74, left hemisphere 56.7
Substantia nigra
nTPM: 82.9
1916 Female, age 42, unknown 98.1
2241 Male, age 72, unknown 94.9
1889 Female, age 72, unknown 93.1
1851 Male, age 51, unknown 89.0
2409 Female, age 72, unknown 84.9
1941 Male, age 53, unknown 83.0
2699 Male, age 18, unknown 75.2
2590 Female, age 75, unknown 74.7
2583 Male, age 75, right hemisphere 72.9
2665 Male, age 74, both hemispheres 63.4
Superior colliculus
nTPM: 82.4
2587 Male, age 74, left hemisphere 107.7
2261 Male, age 18, unknown 89.7
2087 Female, age 72, unknown 89.4
1796 Male, age 53, unknown 86.0
1913 Female, age 42, unknown 81.5
1995 Male, age 72, unknown 81.2
1839 Male, age 51, unknown 78.4
2668 Female, age 75, unknown 75.8
1895 Male, age 76, right hemisphere 70.7
2664 Male, age 75, both hemispheres 63.6
Ventral tegmental area
nTPM: 86.2
2410 Female, age 72, unknown 99.1
1915 Female, age 42, unknown 91.1
1942 Male, age 51, unknown 85.0
2021 Male, age 53, unknown 81.5
2223 Female, age 72, unknown 80.7
2218 Male, age 76, both hemispheres 79.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 78.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 78.1
Samples: 139

Max nTPM: 357.7
Min nTPM: 24.5
Std nTPM: 51.7
Median nTPM: 61.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 357.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 270.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 263.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 239.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 226.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 216.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 191.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 180.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 176.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 162.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 161.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 138.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 137.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 134.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 133.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 131.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 130.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 127.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 121.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 121.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 118.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 116.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 114.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 107.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 106.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 101.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 94.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 93.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 93.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 92.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 91.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 86.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 86.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 84.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 84.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 83.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 82.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 82.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 81.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 81.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 79.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 78.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 78.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 76.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 76.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 75.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 72.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 72.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 72.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 71.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 70.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 69.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 68.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 68.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 68.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 66.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 64.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 64.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 64.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 63.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 63.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 63.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 62.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 62.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 62.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 61.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 60.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 60.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 59.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 59.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 59.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 58.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 58.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 57.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 57.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 57.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 57.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 56.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 55.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 55.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 54.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 54.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 53.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 53.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 53.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 52.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 52.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 52.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 52.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 52.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 51.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 49.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 48.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 48.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 48.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 47.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 47.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 46.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 46.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 45.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 44.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 43.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 43.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 42.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 42.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 42.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 41.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 41.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 41.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 40.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 37.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 37.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 36.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 36.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 35.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 33.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 30.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 28.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 26.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 24.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 371.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 371.2
FF:10158-103A5 76 years, female 371.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 119.2
Pig sample Sample description nTPM
Midbrain
nTPM: 107.4
Samples: 4

Max nTPM: 114.6
Min nTPM: 94.7
Sample A Female 109.1
Sample B Female 94.7
Sample C Male 111.3
Sample D Male 114.6
Periaqueductal gray
nTPM: 111.3
Samples: 3

Max nTPM: 124.8
Min nTPM: 104.5
Sample B Female 104.5
Sample C Male 104.6
Sample D Male 124.8
Substantia nigra
nTPM: 100.4
Samples: 4

Max nTPM: 127.3
Min nTPM: 81.7
Sample A Female 127.3
Sample B Female 88.4
Sample C Male 104.2
Sample D Male 81.7
Superior colliculi
nTPM: 119.2
Samples: 4

Max nTPM: 128.6
Min nTPM: 111.2
Sample A Female 128.6
Sample B Female 125.6
Sample C Male 111.3
Sample D Male 111.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 235.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 235.4
Samples: 4

Max nTPM: 268.8
Min nTPM: 192.1
Sample A Male 192.1
Sample B Male 218.8
Sample C Female 268.8
Sample D Female 262.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 17.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.6
69735138 Antisense, RP_050503_02_B08, Mouse strain C57BL/6J (56 days, male) 17.6

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