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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:61.6 nTPM
HPA:61.6 nTPM
GTEx:56.7 nTPM
FANTOM5:370.1 Scaled Tags Per Million
Pig:154.9 nTPM
Mouse:153.4 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 61.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 61.6
2666 Male, age 74, left hemisphere 71.9
2411 Female, age 72, unknown 64.4
2219 Male, age 76, both hemispheres 64.3
1827 Male, age 72, unknown 62.2
1830 Male, age 51, unknown 62.0
2586 Male, age 75, left hemisphere 61.6
1833 Male, age 53, unknown 61.3
1870 Female, age 42, unknown 57.5
2828 Female, age 72, unknown 56.8
2019 Male, age 18, unknown 54.3
Dorsal raphe nucleus
nTPM: 50.0
2750 Male, age 76, both hemispheres 63.1
2047 Male, age 72, unknown 51.9
1828 Male, age 53, unknown 51.4
2016 Female, age 72, unknown 44.3
2298 Female, age 72, unknown 39.3
Inferior colliculus
nTPM: 48.5
2849 Male, age 72, unknown 54.2
1848 Female, age 42, unknown 51.6
2097 Female, age 72, unknown 45.1
1890 Male, age 53, unknown 43.0
Median raphe nucleus
nTPM: 38.9
2220 Male, age 76, midline 38.9
Pedunculopontine tegmental nucleus
nTPM: 44.6
2334 Male, age 80, both hemispheres 57.4
1921 Female, age 85, both hemispheres 52.8
2338 Male, age 61, both hemispheres 23.5
Periaquaductal grey, anterior
nTPM: 58.7
2502 Female, age 75, unknown 68.1
1947 Male, age 18, unknown 60.5
1795 Male, age 51, unknown 47.5
Periaquaductal grey, dorsal
nTPM: 40.8
2464 Female, age 72, unknown 55.1
1840 Male, age 53, unknown 41.7
1831 Male, age 72, unknown 40.2
2850 Male, age 76, both hemispheres 26.1
Periaquaductal grey, lateral
nTPM: 36.4
2053 Male, age 18, unknown 44.8
2272 Male, age 74, both hemispheres 37.6
2140 Male, age 76, both hemispheres 26.7
Pretectal area
nTPM: 46.6
2825 Male, age 18, unknown 53.8
1816 Male, age 51, unknown 52.6
2407 Male, age 75, both hemispheres 51.5
1815 Male, age 53, unknown 51.2
1944 Female, age 72, unknown 49.2
1817 Female, age 42, unknown 46.7
2007 Male, age 72, unknown 46.1
2224 Female, age 72, unknown 42.4
2316 Male, age 76, right hemisphere 41.4
2273 Male, age 74, both hemispheres 40.8
2667 Female, age 75, unknown 36.5
Red nucleus
nTPM: 58.0
1821 Female, age 72, unknown 65.3
2588 Male, age 74, left hemisphere 64.8
1865 Male, age 51, unknown 63.6
2823 Male, age 76, right hemisphere 63.5
1904 Male, age 53, unknown 59.4
1954 Female, age 42, unknown 58.8
2503 Female, age 72, unknown 57.7
2227 Male, age 72, unknown 56.2
2769 Male, age 72, unknown 55.5
2584 Male, age 75, left hemisphere 55.2
2785 Male, age 18, unknown 53.9
2725 Female, age 75, unknown 42.2
Substantia nigra
nTPM: 61.0
1941 Male, age 53, unknown 74.7
2665 Male, age 74, both hemispheres 69.0
1916 Female, age 42, unknown 68.4
2241 Male, age 72, unknown 66.3
2583 Male, age 75, right hemisphere 64.9
1851 Male, age 51, unknown 63.8
2699 Male, age 18, unknown 57.5
2590 Female, age 75, unknown 52.1
1889 Female, age 72, unknown 49.3
2409 Female, age 72, unknown 43.7
Superior colliculus
nTPM: 55.1
2668 Female, age 75, unknown 84.8
1839 Male, age 51, unknown 57.8
2587 Male, age 74, left hemisphere 56.4
1895 Male, age 76, right hemisphere 55.9
2664 Male, age 75, both hemispheres 55.6
1913 Female, age 42, unknown 54.0
2261 Male, age 18, unknown 49.0
1796 Male, age 53, unknown 48.6
1995 Male, age 72, unknown 45.2
2087 Female, age 72, unknown 43.2
Ventral tegmental area
nTPM: 53.3
2410 Female, age 72, unknown 72.3
2223 Female, age 72, unknown 55.8
2218 Male, age 76, both hemispheres 52.7
1915 Female, age 42, unknown 50.0
1942 Male, age 51, unknown 45.8
2021 Male, age 53, unknown 43.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 56.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 56.7
Samples: 139

Max nTPM: 103.4
Min nTPM: 28.9
Std nTPM: 11.7
Median nTPM: 54.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 103.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 88.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 87.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 81.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 78.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 77.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 76.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 75.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 75.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 74.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 73.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 72.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 70.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 69.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 69.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 68.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 68.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 68.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 67.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 67.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 67.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 67.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 67.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 66.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 66.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 65.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 64.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 64.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 64.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 63.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 62.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 62.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 62.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 62.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 62.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 62.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 62.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 62.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 61.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 61.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 61.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 60.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 60.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 60.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 60.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 59.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 59.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 59.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 59.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 59.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 59.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 58.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 58.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 57.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 57.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 56.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 55.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 55.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 54.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 54.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 54.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 54.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 54.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 54.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 54.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 54.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 54.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 54.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 54.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 53.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 53.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 53.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 53.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 53.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 53.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 52.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 52.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 52.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 52.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 52.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 51.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 51.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 51.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 51.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 51.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 51.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 51.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 50.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 50.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 49.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 49.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 48.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 48.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 47.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 47.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 47.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 47.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 46.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 46.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 45.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 44.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 44.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 43.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 42.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 42.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 42.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 41.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 41.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 40.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 40.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 39.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 38.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 36.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 36.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 35.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 35.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 28.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 370.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 370.1
FF:10158-103A5 76 years, female 370.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 154.9
Pig sample Sample description nTPM
Midbrain
nTPM: 154.9
Samples: 4

Max nTPM: 190.7
Min nTPM: 130.5
Sample A Female 190.7
Sample B Female 135.0
Sample C Male 163.3
Sample D Male 130.5
Periaqueductal gray
nTPM: 122.3
Samples: 3

Max nTPM: 127.9
Min nTPM: 112.4
Sample B Female 126.7
Sample C Male 127.9
Sample D Male 112.4
Substantia nigra
nTPM: 154.6
Samples: 4

Max nTPM: 171.9
Min nTPM: 106.1
Sample A Female 169.5
Sample B Female 106.1
Sample C Male 170.7
Sample D Male 171.9
Superior colliculi
nTPM: 129.6
Samples: 4

Max nTPM: 153.4
Min nTPM: 83.7
Sample A Female 130.7
Sample B Female 83.7
Sample C Male 150.6
Sample D Male 153.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 153.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 153.4
Samples: 4

Max nTPM: 164.8
Min nTPM: 122.5
Sample A Male 122.5
Sample B Male 163.5
Sample C Female 164.8
Sample D Female 162.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
74003383 Antisense, RP_051130_01_E10, Mouse strain C57BL/6J (56 days, male) 1.6

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