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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:123.9 nTPM
HPA:123.9 nTPM
GTEx:168.4 nTPM
FANTOM5:261.2 Scaled Tags Per Million
Pig:155.8 nTPM
Mouse:385.6 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 123.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 111.0
1870 Female, age 42, unknown 123.5
2019 Male, age 18, unknown 121.8
1830 Male, age 51, unknown 114.9
1833 Male, age 53, unknown 113.2
2411 Female, age 72, unknown 112.6
2586 Male, age 75, left hemisphere 110.0
2828 Female, age 72, unknown 106.7
1827 Male, age 72, unknown 105.5
2219 Male, age 76, both hemispheres 101.8
2666 Male, age 74, left hemisphere 100.3
Dorsal raphe nucleus
nTPM: 110.9
1828 Male, age 53, unknown 119.0
2750 Male, age 76, both hemispheres 112.5
2016 Female, age 72, unknown 111.1
2298 Female, age 72, unknown 106.1
2047 Male, age 72, unknown 106.0
Inferior colliculus
nTPM: 113.4
1890 Male, age 53, unknown 119.4
1848 Female, age 42, unknown 114.4
2097 Female, age 72, unknown 114.3
2849 Male, age 72, unknown 105.5
Median raphe nucleus
nTPM: 103.8
2220 Male, age 76, midline 103.8
Pedunculopontine tegmental nucleus
nTPM: 107.3
1921 Female, age 85, both hemispheres 109.5
2334 Male, age 80, both hemispheres 107.3
2338 Male, age 61, both hemispheres 105.2
Periaquaductal grey, anterior
nTPM: 104.8
1947 Male, age 18, unknown 107.0
2502 Female, age 75, unknown 106.7
1795 Male, age 51, unknown 100.6
Periaquaductal grey, dorsal
nTPM: 105.0
2850 Male, age 76, both hemispheres 108.2
2464 Female, age 72, unknown 106.6
1831 Male, age 72, unknown 103.8
1840 Male, age 53, unknown 101.4
Periaquaductal grey, lateral
nTPM: 105.8
2272 Male, age 74, both hemispheres 106.6
2140 Male, age 76, both hemispheres 105.6
2053 Male, age 18, unknown 105.1
Pretectal area
nTPM: 109.3
2007 Male, age 72, unknown 115.8
1817 Female, age 42, unknown 115.0
2273 Male, age 74, both hemispheres 111.7
2224 Female, age 72, unknown 110.7
2667 Female, age 75, unknown 110.0
1815 Male, age 53, unknown 109.1
2316 Male, age 76, right hemisphere 107.5
2407 Male, age 75, both hemispheres 107.4
1944 Female, age 72, unknown 105.6
2825 Male, age 18, unknown 104.8
1816 Male, age 51, unknown 104.5
Red nucleus
nTPM: 123.9
1821 Female, age 72, unknown 141.9
2823 Male, age 76, right hemisphere 135.1
1865 Male, age 51, unknown 132.2
1954 Female, age 42, unknown 129.6
1904 Male, age 53, unknown 126.9
2769 Male, age 72, unknown 125.9
2227 Male, age 72, unknown 125.2
2503 Female, age 72, unknown 122.5
2785 Male, age 18, unknown 118.4
2725 Female, age 75, unknown 114.4
2588 Male, age 74, left hemisphere 109.7
2584 Male, age 75, left hemisphere 104.6
Substantia nigra
nTPM: 110.4
1889 Female, age 72, unknown 119.3
2241 Male, age 72, unknown 113.9
1851 Male, age 51, unknown 113.3
2699 Male, age 18, unknown 112.3
2409 Female, age 72, unknown 110.5
1916 Female, age 42, unknown 109.2
2583 Male, age 75, right hemisphere 109.0
2590 Female, age 75, unknown 108.8
1941 Male, age 53, unknown 108.6
2665 Male, age 74, both hemispheres 99.2
Superior colliculus
nTPM: 110.1
2587 Male, age 74, left hemisphere 115.4
1913 Female, age 42, unknown 115.3
1995 Male, age 72, unknown 115.1
2668 Female, age 75, unknown 114.1
1895 Male, age 76, right hemisphere 113.7
1839 Male, age 51, unknown 108.3
2664 Male, age 75, both hemispheres 106.9
2087 Female, age 72, unknown 104.9
2261 Male, age 18, unknown 104.2
1796 Male, age 53, unknown 103.1
Ventral tegmental area
nTPM: 109.2
2410 Female, age 72, unknown 115.5
2223 Female, age 72, unknown 114.7
1915 Female, age 42, unknown 108.6
1942 Male, age 51, unknown 107.1
2218 Male, age 76, both hemispheres 104.9
2021 Male, age 53, unknown 104.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 168.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 168.4
Samples: 139

Max nTPM: 334.7
Min nTPM: 82.2
Std nTPM: 44.9
Median nTPM: 162.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 334.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 274.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 268.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 264.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 255.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 252.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 251.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 244.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 244.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 241.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 240.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 238.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 236.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 232.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 231.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 229.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 226.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 224.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 223.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 222.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 220.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 220.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 218.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 215.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 212.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 208.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 207.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 205.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 203.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 202.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 201.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 200.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 200.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 197.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 196.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 193.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 192.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 192.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 191.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 190.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 190.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 189.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 188.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 184.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 183.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 182.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 182.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 182.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 182.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 181.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 180.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 180.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 180.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 176.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 175.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 174.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 173.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 172.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 170.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 170.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 170.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 169.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 169.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 166.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 165.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 165.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 165.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 163.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 163.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 162.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 160.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 159.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 159.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 159.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 159.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 157.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 157.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 157.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 156.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 156.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 155.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 152.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 151.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 150.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 147.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 147.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 146.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 146.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 145.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 144.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 144.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 142.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 142.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 141.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 141.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 140.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 140.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 139.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 139.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 139.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 138.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 138.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 136.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 135.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 135.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 132.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 132.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 131.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 130.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 129.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 128.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 128.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 126.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 126.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 124.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 123.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 123.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 122.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 122.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 121.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 121.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 120.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 120.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 119.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 119.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 119.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 114.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 113.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 112.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 104.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 98.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 97.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 95.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 94.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 91.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 82.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 82.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 261.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 261.2
FF:10158-103A5 76 years, female 261.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 155.8
Pig sample Sample description nTPM
Midbrain
nTPM: 155.8
Samples: 4

Max nTPM: 266.6
Min nTPM: 101.9
Sample A Female 266.6
Sample B Female 135.3
Sample C Male 119.3
Sample D Male 101.9
Periaqueductal gray
nTPM: 98.9
Samples: 3

Max nTPM: 107.3
Min nTPM: 92.3
Sample B Female 107.3
Sample C Male 92.3
Sample D Male 97.2
Substantia nigra
nTPM: 137.9
Samples: 4

Max nTPM: 179.3
Min nTPM: 105.4
Sample A Female 179.3
Sample B Female 122.4
Sample C Male 105.4
Sample D Male 144.6
Superior colliculi
nTPM: 153.1
Samples: 4

Max nTPM: 185.1
Min nTPM: 135.0
Sample A Female 185.1
Sample B Female 139.9
Sample C Male 152.4
Sample D Male 135.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 385.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 385.7
Samples: 4

Max nTPM: 400.7
Min nTPM: 360.3
Sample A Male 400.7
Sample B Male 360.3
Sample C Female 382.5
Sample D Female 399.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
2067 Antisense, RP_040604_01_E04, Mouse strain C57BL/6J (56 days, male) 0.8
100144162 Antisense, RP_110421_02_A07, Mouse strain C57BL/6J (56 days, male) 0.5

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