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GPBP1
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  • GPBP1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:68.0 nTPM
HPA:68.0 nTPM
GTEx:53.4 nTPM
FANTOM5:110.9 Scaled Tags Per Million
Pig:66.0 nTPM
Mouse:67.0 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 68.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65.4
1870 Female, age 42, unknown 68.2
1827 Male, age 72, unknown 67.7
2019 Male, age 18, unknown 67.1
2411 Female, age 72, unknown 66.8
1830 Male, age 51, unknown 65.8
1833 Male, age 53, unknown 65.6
2828 Female, age 72, unknown 64.0
2666 Male, age 74, left hemisphere 63.6
2219 Male, age 76, both hemispheres 63.1
2586 Male, age 75, left hemisphere 62.1
Dorsal raphe nucleus
nTPM: 65.0
2016 Female, age 72, unknown 68.5
1828 Male, age 53, unknown 65.0
2750 Male, age 76, both hemispheres 64.9
2298 Female, age 72, unknown 64.8
2047 Male, age 72, unknown 61.6
Inferior colliculus
nTPM: 66.4
1848 Female, age 42, unknown 67.4
2849 Male, age 72, unknown 66.5
2097 Female, age 72, unknown 66.2
1890 Male, age 53, unknown 65.3
Median raphe nucleus
nTPM: 61.6
2220 Male, age 76, midline 61.6
Pedunculopontine tegmental nucleus
nTPM: 65.1
2334 Male, age 80, both hemispheres 66.4
1921 Female, age 85, both hemispheres 66.2
2338 Male, age 61, both hemispheres 62.8
Periaquaductal grey, anterior
nTPM: 64.9
1947 Male, age 18, unknown 66.4
2502 Female, age 75, unknown 65.6
1795 Male, age 51, unknown 62.7
Periaquaductal grey, dorsal
nTPM: 67.3
1840 Male, age 53, unknown 69.6
1831 Male, age 72, unknown 67.0
2850 Male, age 76, both hemispheres 67.0
2464 Female, age 72, unknown 65.5
Periaquaductal grey, lateral
nTPM: 65.6
2053 Male, age 18, unknown 66.7
2140 Male, age 76, both hemispheres 66.2
2272 Male, age 74, both hemispheres 63.9
Pretectal area
nTPM: 65.9
1815 Male, age 53, unknown 68.2
1817 Female, age 42, unknown 68.1
2007 Male, age 72, unknown 68.0
2825 Male, age 18, unknown 66.4
1944 Female, age 72, unknown 66.1
1816 Male, age 51, unknown 65.9
2316 Male, age 76, right hemisphere 65.3
2224 Female, age 72, unknown 65.2
2273 Male, age 74, both hemispheres 64.7
2407 Male, age 75, both hemispheres 64.3
2667 Female, age 75, unknown 62.9
Red nucleus
nTPM: 68.0
2503 Female, age 72, unknown 72.8
1821 Female, age 72, unknown 70.5
1865 Male, age 51, unknown 69.8
2725 Female, age 75, unknown 69.7
1954 Female, age 42, unknown 69.3
2588 Male, age 74, left hemisphere 68.1
2823 Male, age 76, right hemisphere 67.2
1904 Male, age 53, unknown 66.2
2769 Male, age 72, unknown 66.2
2227 Male, age 72, unknown 65.8
2785 Male, age 18, unknown 65.8
2584 Male, age 75, left hemisphere 65.2
Substantia nigra
nTPM: 64.4
1889 Female, age 72, unknown 67.5
2583 Male, age 75, right hemisphere 66.0
2590 Female, age 75, unknown 65.9
2241 Male, age 72, unknown 64.7
2409 Female, age 72, unknown 64.0
2699 Male, age 18, unknown 64.0
2665 Male, age 74, both hemispheres 63.9
1941 Male, age 53, unknown 63.6
1851 Male, age 51, unknown 63.4
1916 Female, age 42, unknown 60.6
Superior colliculus
nTPM: 66.5
1895 Male, age 76, right hemisphere 69.4
1995 Male, age 72, unknown 69.4
1913 Female, age 42, unknown 68.5
2587 Male, age 74, left hemisphere 68.2
1839 Male, age 51, unknown 67.4
2668 Female, age 75, unknown 65.5
1796 Male, age 53, unknown 65.0
2664 Male, age 75, both hemispheres 64.0
2261 Male, age 18, unknown 63.9
2087 Female, age 72, unknown 63.6
Ventral tegmental area
nTPM: 63.1
2410 Female, age 72, unknown 64.4
2223 Female, age 72, unknown 63.6
1915 Female, age 42, unknown 63.4
1942 Male, age 51, unknown 63.2
2021 Male, age 53, unknown 63.0
2218 Male, age 76, both hemispheres 60.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 53.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 53.4
Samples: 139

Max nTPM: 119.8
Min nTPM: 32.9
Std nTPM: 14.8
Median nTPM: 49.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 119.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 106.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 96.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 93.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 91.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 88.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 86.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 85.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 84.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 81.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 80.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 79.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 75.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 74.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 72.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 69.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 67.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 65.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 65.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 64.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 64.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 64.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 63.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 63.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 62.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 61.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 60.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 59.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 59.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 59.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 58.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 58.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 58.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 57.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 56.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 56.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 56.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 56.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 55.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 54.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 54.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 54.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 53.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 53.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 52.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 52.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 52.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 52.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 51.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 51.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 51.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 51.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 50.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 50.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 50.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 50.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 50.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 49.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 49.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 49.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 49.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 48.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 48.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 48.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 48.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 48.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 48.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 48.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 48.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 47.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 47.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 47.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 47.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 47.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 46.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 46.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 46.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 46.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 46.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 46.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 46.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 46.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 45.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 45.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 44.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 44.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 43.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 43.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 43.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 43.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 43.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 43.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 42.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 42.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 42.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 42.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 42.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 42.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 41.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 41.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 41.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 41.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 41.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 41.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 39.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 39.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 39.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 39.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 39.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 39.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 39.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 39.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 38.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 38.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 38.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 37.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 36.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 36.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 36.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 35.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 35.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 35.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 32.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 110.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 110.9
FF:10158-103A5 76 years, female 110.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.0
Pig sample Sample description nTPM
Midbrain
nTPM: 66.0
Samples: 4

Max nTPM: 76.5
Min nTPM: 61.9
Sample A Female 76.5
Sample B Female 61.9
Sample C Male 63.1
Sample D Male 62.3
Periaqueductal gray
nTPM: 55.8
Samples: 3

Max nTPM: 57.8
Min nTPM: 52.4
Sample B Female 52.4
Sample C Male 57.8
Sample D Male 57.2
Substantia nigra
nTPM: 56.1
Samples: 4

Max nTPM: 65.8
Min nTPM: 49.7
Sample A Female 65.8
Sample B Female 49.7
Sample C Male 54.1
Sample D Male 54.6
Superior colliculi
nTPM: 63.3
Samples: 4

Max nTPM: 70.7
Min nTPM: 51.8
Sample A Female 70.7
Sample B Female 51.8
Sample C Male 65.1
Sample D Male 65.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 67.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 67.0
Samples: 4

Max nTPM: 72.6
Min nTPM: 61.6
Sample A Male 61.6
Sample B Male 69.5
Sample C Female 72.6
Sample D Female 64.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
532735 Antisense, RP_040825_01_H09, Mouse strain C57BL/6J (56 days, male) 0.6

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