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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:150.6 nTPM
HPA:150.6 nTPM
GTEx:199.3 nTPM
FANTOM5:141.1 Scaled Tags Per Million
Pig:86.0 nTPM
Mouse:52.5 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 150.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 128.6
1827 Male, age 72, unknown 137.7
1870 Female, age 42, unknown 137.3
2411 Female, age 72, unknown 137.2
2828 Female, age 72, unknown 131.8
1833 Male, age 53, unknown 128.6
1830 Male, age 51, unknown 126.3
2019 Male, age 18, unknown 125.2
2219 Male, age 76, both hemispheres 124.1
2586 Male, age 75, left hemisphere 123.0
2666 Male, age 74, left hemisphere 114.8
Dorsal raphe nucleus
nTPM: 150.6
2298 Female, age 72, unknown 168.1
2016 Female, age 72, unknown 155.1
1828 Male, age 53, unknown 149.8
2047 Male, age 72, unknown 144.3
2750 Male, age 76, both hemispheres 135.4
Inferior colliculus
nTPM: 143.0
2097 Female, age 72, unknown 155.1
1848 Female, age 42, unknown 141.0
1890 Male, age 53, unknown 139.2
2849 Male, age 72, unknown 136.9
Median raphe nucleus
nTPM: 135.3
2220 Male, age 76, midline 135.3
Pedunculopontine tegmental nucleus
nTPM: 140.0
2334 Male, age 80, both hemispheres 145.6
1921 Female, age 85, both hemispheres 139.5
2338 Male, age 61, both hemispheres 135.0
Periaquaductal grey, anterior
nTPM: 131.4
1795 Male, age 51, unknown 134.5
1947 Male, age 18, unknown 132.0
2502 Female, age 75, unknown 127.8
Periaquaductal grey, dorsal
nTPM: 145.9
2850 Male, age 76, both hemispheres 155.9
1840 Male, age 53, unknown 154.7
2464 Female, age 72, unknown 137.4
1831 Male, age 72, unknown 135.7
Periaquaductal grey, lateral
nTPM: 146.1
2140 Male, age 76, both hemispheres 149.7
2272 Male, age 74, both hemispheres 148.7
2053 Male, age 18, unknown 139.9
Pretectal area
nTPM: 139.9
2273 Male, age 74, both hemispheres 158.9
2224 Female, age 72, unknown 154.9
1944 Female, age 72, unknown 144.1
2825 Male, age 18, unknown 142.7
2667 Female, age 75, unknown 141.6
1817 Female, age 42, unknown 139.5
1816 Male, age 51, unknown 137.3
1815 Male, age 53, unknown 135.4
2316 Male, age 76, right hemisphere 132.6
2007 Male, age 72, unknown 130.8
2407 Male, age 75, both hemispheres 121.6
Red nucleus
nTPM: 130.4
1821 Female, age 72, unknown 145.1
2503 Female, age 72, unknown 139.4
2725 Female, age 75, unknown 136.6
1954 Female, age 42, unknown 135.4
2227 Male, age 72, unknown 134.6
2769 Male, age 72, unknown 132.6
1865 Male, age 51, unknown 129.4
2823 Male, age 76, right hemisphere 128.7
1904 Male, age 53, unknown 127.6
2785 Male, age 18, unknown 121.5
2588 Male, age 74, left hemisphere 119.4
2584 Male, age 75, left hemisphere 115.0
Substantia nigra
nTPM: 140.4
2699 Male, age 18, unknown 153.4
1916 Female, age 42, unknown 147.6
1851 Male, age 51, unknown 146.0
2241 Male, age 72, unknown 143.5
2590 Female, age 75, unknown 141.0
1889 Female, age 72, unknown 139.9
1941 Male, age 53, unknown 137.4
2665 Male, age 74, both hemispheres 135.1
2583 Male, age 75, right hemisphere 131.3
2409 Female, age 72, unknown 128.9
Superior colliculus
nTPM: 133.7
2587 Male, age 74, left hemisphere 140.4
1995 Male, age 72, unknown 139.1
2261 Male, age 18, unknown 137.1
2087 Female, age 72, unknown 136.5
1796 Male, age 53, unknown 135.3
1895 Male, age 76, right hemisphere 133.0
1913 Female, age 42, unknown 132.7
1839 Male, age 51, unknown 131.2
2668 Female, age 75, unknown 127.7
2664 Male, age 75, both hemispheres 124.3
Ventral tegmental area
nTPM: 140.8
2410 Female, age 72, unknown 147.2
1915 Female, age 42, unknown 144.4
2021 Male, age 53, unknown 142.4
1942 Male, age 51, unknown 138.8
2223 Female, age 72, unknown 137.7
2218 Male, age 76, both hemispheres 134.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 199.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 199.3
Samples: 139

Max nTPM: 389.7
Min nTPM: 95.9
Std nTPM: 56.0
Median nTPM: 190.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 389.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 378.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 370.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 335.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 331.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 313.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 301.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 300.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 299.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 299.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 284.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 278.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 276.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 275.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 274.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 273.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 261.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 261.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 260.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 258.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 255.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 253.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 253.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 250.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 250.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 247.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 245.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 242.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 237.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 236.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 234.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 233.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 230.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 229.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 228.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 225.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 224.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 221.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 220.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 220.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 218.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 218.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 217.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 216.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 216.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 213.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 213.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 213.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 212.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 212.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 209.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 207.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 206.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 206.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 205.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 203.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 203.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 203.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 202.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 201.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 200.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 199.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 196.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 196.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 192.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 192.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 191.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 191.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 190.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 190.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 189.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 187.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 186.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 186.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 186.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 185.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 184.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 180.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 180.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 179.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 177.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 177.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 176.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 176.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 175.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 175.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 175.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 175.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 174.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 174.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 173.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 172.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 171.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 170.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 169.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 169.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 166.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 166.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 166.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 164.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 159.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 159.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 158.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 157.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 155.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 154.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 153.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 153.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 153.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 153.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 152.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 151.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 150.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 150.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 149.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 149.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 148.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 148.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 147.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 146.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 145.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 144.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 143.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 138.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 133.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 133.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 132.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 127.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 127.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 123.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 120.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 119.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 117.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 115.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 114.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 111.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 107.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 95.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 141.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 141.1
FF:10158-103A5 76 years, female 141.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 86.0
Pig sample Sample description nTPM
Midbrain
nTPM: 86.0
Samples: 4

Max nTPM: 144.6
Min nTPM: 54.5
Sample A Female 144.6
Sample B Female 74.6
Sample C Male 70.2
Sample D Male 54.5
Periaqueductal gray
nTPM: 68.1
Samples: 3

Max nTPM: 74.5
Min nTPM: 63.9
Sample B Female 63.9
Sample C Male 74.5
Sample D Male 66.0
Substantia nigra
nTPM: 74.5
Samples: 4

Max nTPM: 100.5
Min nTPM: 60.6
Sample A Female 100.5
Sample B Female 63.7
Sample C Male 73.1
Sample D Male 60.6
Superior colliculi
nTPM: 80.1
Samples: 4

Max nTPM: 103.9
Min nTPM: 61.7
Sample A Female 82.8
Sample B Female 103.9
Sample C Male 72.0
Sample D Male 61.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 52.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 52.6
Samples: 4

Max nTPM: 55.2
Min nTPM: 50.5
Sample A Male 51.4
Sample B Male 50.5
Sample C Female 55.2
Sample D Female 53.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
71991720 Antisense, RP_051012_03_C12, Mouse strain C57BL/6J (56 days, male) 4.6
70795910 Antisense, RP_050712_02_B12, Mouse strain C57BL/6J (56 days, male) 0.1

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