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ADCYAP1R1
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:88.9 nTPM
HPA:88.9 nTPM
FANTOM5:74.0 Scaled Tags Per Million
Pig:57.7 nTPM
Allen mouse:8.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 88.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 46.3
2301 Female, age 85, both hemispheres 53.7
1984 Male, age 76, both hemispheres 52.5
2090 Male, age 80, both hemispheres 47.5
2188 Female, age 91, both hemispheres 31.4
Dorsal cochlear nucleus
nTPM: 70.4
2802 Male, age 74, right hemisphere 86.7
2370 Male, age 61, both hemispheres 79.6
2058 Male, age 76, both hemispheres 71.4
2378 Male, age 80, both hemispheres 68.9
2187 Female, age 91, both hemispheres 45.3
Dorsal tegmental nucleus
nTPM: 59.1
1936 Male, age 76, left hemisphere 67.2
2326 Male, age 74, both hemispheres 60.4
2083 Male, age 80, both hemispheres 59.7
2358 Male, age 61, both hemispheres 49.0
Dorsolateral tegmental area
nTPM: 52.7
2141 Male, age 76, both hemispheres 76.9
2360 Male, age 74, both hemispheres 58.8
2654 Male, age 80, both hemispheres 57.8
2751 Female, age 85, both hemispheres 48.4
2337 Male, age 61, both hemispheres 21.9
Kolliker-Fuse nucleus
nTPM: 57.2
2315 Male, age 76, right hemisphere 76.0
2163 Male, age 80, both hemispheres 54.6
2793 Female, age 91, left hemisphere 41.0
Lateral lemniscal nuclei
nTPM: 75.6
2036 Male, age 80, both hemispheres 100.9
2169 Male, age 76, both hemispheres 87.6
2746 Female, age 85, left hemisphere 82.9
2453 Male, age 74, right hemisphere 63.1
2320 Female, age 91, left hemisphere 43.5
Lateral parabrachial nucleus
nTPM: 69.1
2139 Female, age 85, right hemisphere 110.6
2013 Male, age 80, both hemispheres 66.8
2790 Male, age 61, both hemispheres 51.2
2792 Male, age 76, both hemispheres 47.9
Lateral vestibular nucleus
nTPM: 60.9
2184 Male, age 76, both hemispheres 65.3
2311 Male, age 80, both hemispheres 56.6
Locus coeruleus
nTPM: 88.9
2317 Female, age 72, unknown 103.7
2014 Male, age 55, unknown 98.8
2123 Female, age 91, both hemispheres 91.7
1980 Male, age 76, both hemispheres 89.6
2788 Male, age 74, unknown 84.2
2162 Male, age 80, both hemispheres 82.7
2720 Male, age 74, both hemispheres 71.7
Medial olivary nucleus
nTPM: 53.2
2138 Female, age 91, both hemispheres 87.9
2851 Male, age 80, both hemispheres 53.3
1962 Male, age 76, both hemispheres 41.5
1943 Male, age 61, both hemispheres 30.3
Medial parabrachial nucleus
nTPM: 51.2
2786 Male, age 76, both hemispheres 57.4
2854 Male, age 80, both hemispheres 54.3
2156 Male, age 61, both hemispheres 53.0
2463 Female, age 85, right hemisphere 51.6
2170 Female, age 91, both hemispheres 39.7
Medial periolivary nuclei
nTPM: 76.6
2171 Female, age 85, both hemispheres 105.2
2063 Male, age 76, both hemispheres 104.2
2791 Male, age 74, right hemisphere 72.1
2081 Male, age 80, both hemispheres 54.7
2458 Female, age 91, both hemispheres 47.0
Motor facial nucleus
nTPM: 78.4
2062 Male, age 76, both hemispheres 114.6
2795 Female, age 91, both hemispheres 90.0
2327 Male, age 80, both hemispheres 89.9
2365 Male, age 74, right hemisphere 63.5
2697 Female, age 85, both hemispheres 61.7
2126 Male, age 61, both hemispheres 50.5
Motor trigeminal nucleus
nTPM: 58.7
2079 Male, age 80, both hemispheres 85.7
2309 Male, age 76, both hemispheres 64.1
2560 Male, age 74, both hemispheres 53.7
2335 Male, age 61, both hemispheres 49.3
2321 Female, age 91, both hemispheres 40.8
Nuclei of the trapezoid body
nTPM: 86.2
2735 Female, age 85, both hemispheres 120.3
1983 Male, age 76, both hemispheres 102.7
2166 Male, age 80, both hemispheres 75.5
2368 Female, age 91, both hemispheres 71.5
2159 Male, age 61, both hemispheres 61.0
Paramedian reticular nucleus
nTPM: 50.8
2050 Female, age 85, both hemispheres 64.3
2057 Male, age 80, both hemispheres 49.8
2313 Male, age 61, both hemispheres 48.9
2052 Male, age 76, both hemispheres 40.1
Pontine nuclei
nTPM: 59.6
2787 Female, age 85, both hemispheres 106.6
1968 Male, age 76, left hemisphere 80.6
1863 Male, age 55, unknown 71.0
2115 Male, age 80, left hemisphere 61.2
2727 Male, age 61, right hemisphere 49.8
2109 Female, age 72, unknown 49.1
2319 Female, age 91, both hemispheres 35.2
2454 Male, age 74, left hemisphere 23.3
Pontine raphe nucleus
nTPM: 74.2
2122 Female, age 85, midline 74.7
2853 Male, age 76, midline 73.6
Posteroventral cochlear nucleus
nTPM: 46.4
2371 Male, age 61, both hemispheres 74.9
2752 Female, age 85, both hemispheres 58.5
2070 Male, age 76, both hemispheres 56.7
2341 Male, age 80, both hemispheres 25.2
2135 Female, age 91, both hemispheres 16.9
Principal sensory trigeminal nucleus
nTPM: 67.0
2008 Male, age 80, left hemisphere 92.8
2158 Male, age 61, both hemispheres 70.6
2324 Male, age 76, both hemispheres 65.7
2367 Female, age 91, left hemisphere 39.0
Reticular pontine nucleus, caudal
nTPM: 59.9
2092 Male, age 76, both hemispheres 83.7
2332 Male, age 80, right hemisphere 79.0
2457 Female, age 91, both hemispheres 44.3
2559 Male, age 74, both hemispheres 32.6
Reticular pontine nucleus, oral
nTPM: 51.1
2012 Female, age 85, both hemispheres 73.3
2167 Male, age 76, both hemispheres 60.4
1939 Male, age 80, both hemispheres 53.9
2366 Female, age 91, both hemispheres 36.2
2361 Male, age 74, both hemispheres 31.9
Reticulotegmental nucleus
nTPM: 60.3
2325 Male, age 76, both hemispheres 84.9
2333 Male, age 80, both hemispheres 57.1
2322 Female, age 91, both hemispheres 50.5
2452 Male, age 74, both hemispheres 48.7
Spinal trigeminal nucleus, oral
nTPM: 49.3
1978 Male, age 76, both hemispheres 50.9
2737 Female, age 85, both hemispheres 50.3
2164 Male, age 80, both hemispheres 46.8
Subcoeruleus area
nTPM: 69.1
2089 Male, age 76, left hemisphere 88.4
2451 Male, age 74, both hemispheres 76.3
1958 Male, age 80, both hemispheres 69.3
2323 Female, age 91, left hemisphere 65.9
2369 Female, age 85, left hemisphere 45.3
Superior olive
nTPM: 71.6
1875 Female, age 85, both hemispheres 92.6
2020 Male, age 76, both hemispheres 78.5
2329 Male, age 80, right hemisphere 73.5
2364 Male, age 74, right hemisphere 58.3
2561 Female, age 91, both hemispheres 54.9
Superior vestibular nucleus
nTPM: 67.5
2061 Male, age 76, both hemispheres 74.5
2015 Male, age 80, both hemispheres 64.2
2383 Male, age 74, both hemispheres 63.7
Ventral periolivary nuclei
nTPM: 86.8
2130 Female, age 85, both hemispheres 118.5
2165 Male, age 80, both hemispheres 97.3
2023 Male, age 76, both hemispheres 71.5
2794 Female, age 91, left hemisphere 60.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 66.4
1959 Male, age 76, both hemispheres 83.6
2161 Male, age 80, both hemispheres 77.2
2449 Male, age 74, both hemispheres 65.4
2456 Female, age 91, both hemispheres 61.0
2359 Male, age 61, both hemispheres 56.5
2840 Female, age 85, both hemispheres 54.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 74.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 62.1
FF:10182-103D2 60 years, female 72.6
FF:10165-103B3 76 years, female 51.7
Pons
Scaled Tags Per Million: 74.0
FF:10033-101E6 18-54 years, mixed 74.0

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 57.7
Pig sample Sample description nTPM
Pons
nTPM: 57.7
Samples: 4

Max nTPM: 64.0
Min nTPM: 55.3
Sample A Female 56.0
Sample B Female 64.0
Sample C Male 55.4
Sample D Male 55.3

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 8.6
69236777 Antisense, RP_050331_01_B04, Mouse strain C57BL/6J (56 days, male) 11.0
74988667 Antisense, RP_060315_04_A03, Mouse strain C57BL/6J (56 days, male) 6.1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.