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TP53INP2
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:444.7 nTPM
HPA:444.7 nTPM
GTEx:661.6 nTPM
FANTOM5:794.1 Scaled Tags Per Million
Pig:191.9 nTPM
Mouse:159.9 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 444.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 372.4
2586 Male, age 75, left hemisphere 454.0
1830 Male, age 51, unknown 426.6
1833 Male, age 53, unknown 420.0
2666 Male, age 74, left hemisphere 408.8
1870 Female, age 42, unknown 370.7
2411 Female, age 72, unknown 354.7
2828 Female, age 72, unknown 351.4
2019 Male, age 18, unknown 341.1
2219 Male, age 76, both hemispheres 318.7
1827 Male, age 72, unknown 277.5
Dorsal raphe nucleus
nTPM: 272.1
2750 Male, age 76, both hemispheres 341.3
2016 Female, age 72, unknown 301.3
1828 Male, age 53, unknown 289.3
2047 Male, age 72, unknown 232.2
2298 Female, age 72, unknown 196.7
Inferior colliculus
nTPM: 275.1
2849 Male, age 72, unknown 310.5
1890 Male, age 53, unknown 289.1
1848 Female, age 42, unknown 285.6
2097 Female, age 72, unknown 215.3
Median raphe nucleus
nTPM: 272.3
2220 Male, age 76, midline 272.3
Pedunculopontine tegmental nucleus
nTPM: 383.7
2338 Male, age 61, both hemispheres 492.8
2334 Male, age 80, both hemispheres 377.7
1921 Female, age 85, both hemispheres 280.7
Periaquaductal grey, anterior
nTPM: 259.9
2502 Female, age 75, unknown 281.2
1947 Male, age 18, unknown 262.9
1795 Male, age 51, unknown 235.5
Periaquaductal grey, dorsal
nTPM: 253.6
2464 Female, age 72, unknown 297.4
2850 Male, age 76, both hemispheres 261.9
1831 Male, age 72, unknown 252.7
1840 Male, age 53, unknown 202.5
Periaquaductal grey, lateral
nTPM: 257.4
2053 Male, age 18, unknown 275.3
2272 Male, age 74, both hemispheres 248.6
2140 Male, age 76, both hemispheres 248.1
Pretectal area
nTPM: 257.6
1815 Male, age 53, unknown 329.8
2407 Male, age 75, both hemispheres 299.6
1817 Female, age 42, unknown 287.7
2825 Male, age 18, unknown 287.3
2007 Male, age 72, unknown 269.5
2316 Male, age 76, right hemisphere 268.0
2667 Female, age 75, unknown 222.6
2224 Female, age 72, unknown 221.4
1816 Male, age 51, unknown 219.3
1944 Female, age 72, unknown 216.2
2273 Male, age 74, both hemispheres 211.7
Red nucleus
nTPM: 444.7
2588 Male, age 74, left hemisphere 548.2
1865 Male, age 51, unknown 507.7
2503 Female, age 72, unknown 491.9
2769 Male, age 72, unknown 480.6
2227 Male, age 72, unknown 475.6
1904 Male, age 53, unknown 468.4
1954 Female, age 42, unknown 412.8
1821 Female, age 72, unknown 408.9
2785 Male, age 18, unknown 404.1
2823 Male, age 76, right hemisphere 396.9
2584 Male, age 75, left hemisphere 391.3
2725 Female, age 75, unknown 349.9
Substantia nigra
nTPM: 299.1
2665 Male, age 74, both hemispheres 357.4
2699 Male, age 18, unknown 342.4
2583 Male, age 75, right hemisphere 342.0
2590 Female, age 75, unknown 321.6
1851 Male, age 51, unknown 292.6
2409 Female, age 72, unknown 290.6
1889 Female, age 72, unknown 286.5
1941 Male, age 53, unknown 260.9
2241 Male, age 72, unknown 249.6
1916 Female, age 42, unknown 247.7
Superior colliculus
nTPM: 308.5
1995 Male, age 72, unknown 381.8
2668 Female, age 75, unknown 361.8
1913 Female, age 42, unknown 357.9
1839 Male, age 51, unknown 337.9
2587 Male, age 74, left hemisphere 334.8
2664 Male, age 75, both hemispheres 302.1
1895 Male, age 76, right hemisphere 270.9
1796 Male, age 53, unknown 258.6
2261 Male, age 18, unknown 240.4
2087 Female, age 72, unknown 238.7
Ventral tegmental area
nTPM: 307.1
2223 Female, age 72, unknown 390.7
2410 Female, age 72, unknown 329.6
2021 Male, age 53, unknown 285.0
1942 Male, age 51, unknown 284.3
2218 Male, age 76, both hemispheres 282.3
1915 Female, age 42, unknown 270.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 661.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 661.6
Samples: 139

Max nTPM: 1971.7
Min nTPM: 107.7
Std nTPM: 423.1
Median nTPM: 548.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1971.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1950.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1840.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1802.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1728.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1689.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1672.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1627.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1626.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1556.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1495.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1336.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1309.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1256.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1224.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1221.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1171.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1150.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1140.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1112.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1108.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1067.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1062.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1010.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 998.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 989.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 984.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 983.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 978.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 950.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 948.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 856.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 836.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 833.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 832.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 817.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 796.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 794.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 791.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 788.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 788.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 775.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 749.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 740.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 737.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 735.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 735.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 722.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 714.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 710.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 702.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 701.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 685.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 684.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 676.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 669.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 653.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 649.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 645.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 621.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 616.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 613.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 601.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 599.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 575.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 566.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 564.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 553.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 551.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 548.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 546.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 544.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 538.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 534.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 525.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 520.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 511.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 477.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 474.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 473.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 453.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 450.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 447.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 444.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 438.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 430.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 427.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 423.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 422.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 415.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 408.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 398.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 398.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 393.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 391.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 376.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 370.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 368.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 366.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 362.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 359.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 359.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 353.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 349.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 349.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 348.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 338.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 337.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 334.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 325.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 315.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 314.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 314.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 298.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 292.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 290.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 284.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 275.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 273.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 271.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 267.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 267.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 262.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 258.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 257.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 246.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 244.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 234.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 225.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 223.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 222.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 206.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 202.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 182.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 177.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 171.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 156.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 125.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 107.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 794.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 794.1
FF:10158-103A5 76 years, female 794.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 191.9
Pig sample Sample description nTPM
Midbrain
nTPM: 191.9
Samples: 4

Max nTPM: 363.2
Min nTPM: 96.2
Sample A Female 363.2
Sample B Female 198.5
Sample C Male 109.7
Sample D Male 96.2
Periaqueductal gray
nTPM: 118.4
Samples: 3

Max nTPM: 145.8
Min nTPM: 93.7
Sample B Female 145.8
Sample C Male 93.7
Sample D Male 115.8
Substantia nigra
nTPM: 171.3
Samples: 4

Max nTPM: 279.0
Min nTPM: 104.3
Sample A Female 167.9
Sample B Female 104.3
Sample C Male 133.9
Sample D Male 279.0
Superior colliculi
nTPM: 152.0
Samples: 4

Max nTPM: 194.2
Min nTPM: 89.9
Sample A Female 161.3
Sample B Female 89.9
Sample C Male 162.6
Sample D Male 194.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 159.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 159.9
Samples: 4

Max nTPM: 174.4
Min nTPM: 146.4
Sample A Male 154.2
Sample B Male 146.4
Sample C Female 164.5
Sample D Female 174.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
70192081 Antisense, RP_050517_01_C01, Mouse strain C57BL/6J (56 days, male) 0.4

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