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TP53INP2
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:464.6 nTPM
HPA:464.6 nTPM
FANTOM5:789.1 Scaled Tags Per Million
Pig:141.1 nTPM
Allen mouse:0.5 Expression energy

PONS - Annotated protein expression
Pending normal tissue analysis

PONS - HPA Brain RNA-seq
Max nTPM 464.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 439.3
2188 Female, age 91, both hemispheres 549.9
2301 Female, age 85, both hemispheres 527.9
2090 Male, age 80, both hemispheres 401.1
1984 Male, age 76, both hemispheres 278.3
Dorsal cochlear nucleus
nTPM: 393.6
2802 Male, age 74, right hemisphere 424.2
2370 Male, age 61, both hemispheres 407.0
2378 Male, age 80, both hemispheres 405.1
2187 Female, age 91, both hemispheres 393.0
2058 Male, age 76, both hemispheres 339.0
Dorsal tegmental nucleus
nTPM: 404.4
2358 Male, age 61, both hemispheres 466.4
2083 Male, age 80, both hemispheres 431.4
2326 Male, age 74, both hemispheres 399.6
1936 Male, age 76, left hemisphere 320.2
Dorsolateral tegmental area
nTPM: 393.0
2337 Male, age 61, both hemispheres 621.7
2654 Male, age 80, both hemispheres 437.5
2751 Female, age 85, both hemispheres 374.4
2360 Male, age 74, both hemispheres 278.1
2141 Male, age 76, both hemispheres 253.4
Kolliker-Fuse nucleus
nTPM: 395.3
2793 Female, age 91, left hemisphere 525.4
2163 Male, age 80, both hemispheres 381.7
2315 Male, age 76, right hemisphere 278.7
Lateral lemniscal nuclei
nTPM: 337.5
2320 Female, age 91, left hemisphere 413.8
2036 Male, age 80, both hemispheres 370.0
2453 Male, age 74, right hemisphere 327.5
2169 Male, age 76, both hemispheres 301.4
2746 Female, age 85, left hemisphere 274.8
Lateral parabrachial nucleus
nTPM: 400.6
2790 Male, age 61, both hemispheres 561.5
2792 Male, age 76, both hemispheres 460.7
2013 Male, age 80, both hemispheres 316.3
2139 Female, age 85, right hemisphere 263.8
Lateral vestibular nucleus
nTPM: 410.3
2311 Male, age 80, both hemispheres 461.7
2184 Male, age 76, both hemispheres 358.9
Locus coeruleus
nTPM: 249.4
2720 Male, age 74, both hemispheres 345.1
2162 Male, age 80, both hemispheres 296.0
2317 Female, age 72, unknown 231.5
2123 Female, age 91, both hemispheres 226.2
1980 Male, age 76, both hemispheres 220.8
2788 Male, age 74, unknown 214.4
2014 Male, age 55, unknown 211.5
Medial olivary nucleus
nTPM: 390.0
1962 Male, age 76, both hemispheres 419.0
1943 Male, age 61, both hemispheres 389.7
2851 Male, age 80, both hemispheres 382.6
2138 Female, age 91, both hemispheres 368.7
Medial parabrachial nucleus
nTPM: 402.9
2156 Male, age 61, both hemispheres 522.9
2170 Female, age 91, both hemispheres 412.7
2854 Male, age 80, both hemispheres 366.1
2463 Female, age 85, right hemisphere 358.9
2786 Male, age 76, both hemispheres 354.1
Medial periolivary nuclei
nTPM: 323.0
2458 Female, age 91, both hemispheres 425.9
2081 Male, age 80, both hemispheres 345.7
2171 Female, age 85, both hemispheres 291.7
2063 Male, age 76, both hemispheres 285.5
2791 Male, age 74, right hemisphere 266.0
Motor facial nucleus
nTPM: 368.5
2697 Female, age 85, both hemispheres 494.9
2795 Female, age 91, both hemispheres 407.3
2327 Male, age 80, both hemispheres 381.2
2126 Male, age 61, both hemispheres 369.7
2365 Male, age 74, right hemisphere 295.6
2062 Male, age 76, both hemispheres 262.3
Motor trigeminal nucleus
nTPM: 391.4
2321 Female, age 91, both hemispheres 452.1
2335 Male, age 61, both hemispheres 418.4
2309 Male, age 76, both hemispheres 377.7
2560 Male, age 74, both hemispheres 355.5
2079 Male, age 80, both hemispheres 353.1
Nuclei of the trapezoid body
nTPM: 344.5
2166 Male, age 80, both hemispheres 431.5
2368 Female, age 91, both hemispheres 416.9
2159 Male, age 61, both hemispheres 336.2
1983 Male, age 76, both hemispheres 276.3
2735 Female, age 85, both hemispheres 261.5
Paramedian reticular nucleus
nTPM: 365.8
2052 Male, age 76, both hemispheres 421.4
2313 Male, age 61, both hemispheres 371.5
2057 Male, age 80, both hemispheres 363.8
2050 Female, age 85, both hemispheres 306.3
Pontine nuclei
nTPM: 332.0
2319 Female, age 91, both hemispheres 453.8
2115 Male, age 80, left hemisphere 391.5
2454 Male, age 74, left hemisphere 331.8
1863 Male, age 55, unknown 319.1
1968 Male, age 76, left hemisphere 313.9
2109 Female, age 72, unknown 313.5
2787 Female, age 85, both hemispheres 288.5
2727 Male, age 61, right hemisphere 243.9
Pontine raphe nucleus
nTPM: 274.0
2122 Female, age 85, midline 287.3
2853 Male, age 76, midline 260.6
Posteroventral cochlear nucleus
nTPM: 464.6
2135 Female, age 91, both hemispheres 611.3
2341 Male, age 80, both hemispheres 573.8
2371 Male, age 61, both hemispheres 466.8
2070 Male, age 76, both hemispheres 353.8
2752 Female, age 85, both hemispheres 317.4
Principal sensory trigeminal nucleus
nTPM: 333.5
2367 Female, age 91, left hemisphere 395.1
2324 Male, age 76, both hemispheres 368.6
2158 Male, age 61, both hemispheres 288.7
2008 Male, age 80, left hemisphere 281.5
Reticular pontine nucleus, caudal
nTPM: 376.6
2457 Female, age 91, both hemispheres 428.6
2559 Male, age 74, both hemispheres 369.0
2332 Male, age 80, right hemisphere 364.3
2092 Male, age 76, both hemispheres 344.7
Reticular pontine nucleus, oral
nTPM: 360.4
2366 Female, age 91, both hemispheres 527.4
1939 Male, age 80, both hemispheres 359.9
2167 Male, age 76, both hemispheres 337.5
2012 Female, age 85, both hemispheres 294.6
2361 Male, age 74, both hemispheres 282.5
Reticulotegmental nucleus
nTPM: 382.4
2452 Male, age 74, both hemispheres 422.4
2322 Female, age 91, both hemispheres 400.7
2333 Male, age 80, both hemispheres 397.3
2325 Male, age 76, both hemispheres 309.2
Spinal trigeminal nucleus, oral
nTPM: 340.2
2164 Male, age 80, both hemispheres 438.3
1978 Male, age 76, both hemispheres 306.1
2737 Female, age 85, both hemispheres 276.2
Subcoeruleus area
nTPM: 349.5
2369 Female, age 85, left hemisphere 418.5
2451 Male, age 74, both hemispheres 395.4
1958 Male, age 80, both hemispheres 327.6
2089 Male, age 76, left hemisphere 311.0
2323 Female, age 91, left hemisphere 294.8
Superior olive
nTPM: 362.7
2561 Female, age 91, both hemispheres 451.0
2329 Male, age 80, right hemisphere 420.8
2020 Male, age 76, both hemispheres 381.4
1875 Female, age 85, both hemispheres 293.1
2364 Male, age 74, right hemisphere 267.1
Superior vestibular nucleus
nTPM: 315.6
2015 Male, age 80, both hemispheres 361.1
2061 Male, age 76, both hemispheres 309.9
2383 Male, age 74, both hemispheres 275.7
Ventral periolivary nuclei
nTPM: 359.6
2794 Female, age 91, left hemisphere 420.9
2023 Male, age 76, both hemispheres 380.1
2165 Male, age 80, both hemispheres 362.3
2130 Female, age 85, both hemispheres 275.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 346.7
2456 Female, age 91, both hemispheres 411.2
2161 Male, age 80, both hemispheres 361.4
2359 Male, age 61, both hemispheres 344.9
2840 Female, age 85, both hemispheres 339.5
1959 Male, age 76, both hemispheres 339.4
2449 Male, age 74, both hemispheres 283.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 789.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 789.1
FF:10182-103D2 60 years, female 1020.9
FF:10165-103B3 76 years, female 557.3
Pons
Scaled Tags Per Million: 715.6
FF:10033-101E6 18-54 years, mixed 715.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 141.1
Pig sample Sample description nTPM
Pons
nTPM: 141.2
Samples: 4

Max nTPM: 193.5
Min nTPM: 106.6
Sample A Female 114.0
Sample B Female 106.6
Sample C Male 150.6
Sample D Male 193.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 0.5
70192081 Antisense, RP_050517_01_C01, Mouse strain C57BL/6J (56 days, male) 0.5

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.