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MEF2C
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  • MEF2C
PROTEIN STRUCTURE
ANTIBODIES
AND
VALIDATION
Protein structures
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

MEF2C
Synonyms
Gene descriptioni

Full gene name according to HGNC.

Myocyte enhancer factor 2C
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Read more
Disease related genes
Human disease related genes
Transcription factors
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Read more
Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 5
Cytoband q14.3
Chromosome location (bp) 88717117 - 88904257
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

33
Ensembl ENSG00000081189 (version 103.38)
Entrez gene 4208
HGNC HGNC:6996
UniProt Q06413 (UniProt - Evidence at protein level)
neXtProt NX_Q06413
Antibodypedia MEF2C antibodies


PROTEIN STRUCTUREi

The Structure section provides predicted structures from the Alphafold protein structure database and available experimental structures from Protein Data Bank (PDB).

In the Structure drop-down menu all experimental structures from PDB are available for selection and display. The structures are displayed using the NGL Viewer and can be zoomed-in and rotated either manually or by checking the Autorotate box. The Color scheme can be selected to show the residue index, chain name or confidence score (as B-factors and pLDDT score for experimental and predicted structures, respectively). The positions for available antigen sequences in the structure are shown if Antigens is turned to ON, and the Variants slider can be used to show the positions of clinical and population variants.https://github.com/nglviewer/ngl

Read more

Predicted


Description: Structure prediction from Alphafold project. Structure version 2

# Chains: 1      # Clinical variants: 6      # Population variants: 108

Antigens:

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On

Variants:

Off
Clinical
Population

Color scheme:

Confidence
Residue index
Chain name

Autorotate:

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On



PROTEIN BROWSERi

The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The tabs at the top of the protein view section can be used to switch between the different splice variants to which an antigen has been mapped.

At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.

Below the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues (HsID 50). The region with the lowest possible identity is always selected for antigen design, with a maximum identity of 60% allowed for designing a single-target antigen (read more).

The curve in blue displays the predicted antigenicity i.e. the tendency for different regions of the protein to generate an immune response, with peak regions being predicted to be more antigenic.The curve shows average values based on a sliding window approach using an in-house propensity scale. (read more).

If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius (turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.

Low complexity regions are shown in yellow and InterPro regions in green. Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed (read more), and at the bottom of the protein view is the protein scale.
«
MEF2C-201
MEF2C-202
MEF2C-203
MEF2C-204
MEF2C-205
MEF2C-206
MEF2C-207
MEF2C-209
MEF2C-210
MEF2C-211
MEF2C-212
MEF2C-213
MEF2C-214
MEF2C-216
MEF2C-217
MEF2C-220
MEF2C-221
MEF2C-222
MEF2C-225
MEF2C-226
MEF2C-227
MEF2C-228
MEF2C-229
MEF2C-230
MEF2C-231
MEF2C-232
MEF2C-234
MEF2C-236
MEF2C-239
MEF2C-243
MEF2C-244
MEF2C-249
MEF2C-254
»


PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant UniProt Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
MEF2C-201
ENSP00000340874
ENST00000340208
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
483 aa
52.3 kDa
No 0
MEF2C-202
ENSP00000389610
ENST00000424173
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
463 aa
50.2 kDa
No 0
MEF2C-203
ENSP00000396219
ENST00000437473
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL7 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_b
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
473 aa
51.2 kDa
No 0
MEF2C-204
ENSP00000427286
ENST00000502831
D6RJA7 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
194 aa
21.8 kDa
No 0
MEF2C-205
ENSP00000427163
ENST00000502983
D6RCM6 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
129 aa
14.9 kDa
No 0
MEF2C-206
ENSP00000426465
ENST00000503075
D6RG14 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
87 aa
10.3 kDa
No 0
MEF2C-207
ENSP00000487437
ENST00000503554
A0A0D9SGF3 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0005654 [nucleoplasm]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
327 aa
34.6 kDa
No 0
MEF2C-209
ENSP00000421925
ENST00000504921
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL7 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_b
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
473 aa
51.2 kDa
No 0
MEF2C-210
ENSP00000425636
ENST00000506554
D6RJG6 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0007399 [nervous system development]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
399 aa
43.1 kDa
No 0
MEF2C-211
ENSP00000423656
ENST00000506716
D6R942 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
227 aa
25 kDa
No 0
MEF2C-212
ENSP00000424331
ENST00000507984
D6RB91 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
120 aa
14.1 kDa
No 0
MEF2C-213
ENSP00000423597
ENST00000508569
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL6 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
465 aa
50.3 kDa
No 0
MEF2C-214
ENSP00000426442
ENST00000508610
D6RG21 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
126 aa
14.6 kDa
No 0
MEF2C-216
ENSP00000427309
ENST00000509373
D6RJ95 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0046983 [protein dimerization activity]
Show all
28 aa
3.5 kDa
No 0
MEF2C-217
ENSP00000422390
ENST00000510942
A0A0R4J2G5 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0007399 [nervous system development]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
433 aa
47 kDa
No 0
MEF2C-220
ENSP00000423826
ENST00000513252
D6RC63 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
242 aa
26.6 kDa
No 0
MEF2C-221
ENSP00000424606
ENST00000514015
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0
MEF2C-222
ENSP00000426665
ENST00000514028
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0
MEF2C-225
ENSP00000487538
ENST00000625585
A0A0D9SGI5 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0007399 [nervous system development]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
471 aa
51.1 kDa
No 0
MEF2C-226
ENSP00000487430
ENST00000625674
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
463 aa
50.2 kDa
No 0
MEF2C-227
ENSP00000487184
ENST00000626391
D8L7E9 [Direct mapping]
Myocyte enhancer factor 2c; Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
393 aa
42.5 kDa
No 0
MEF2C-228
ENSP00000487157
ENST00000627170
A0A0D9SG58 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
151 aa
15.9 kDa
No 0
MEF2C-229
ENSP00000486490
ENST00000627659
A0A0D9SFD0 [Direct mapping]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_e; Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0007399 [nervous system development]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
431 aa
46.9 kDa
No 0
MEF2C-230
ENSP00000486932
ENST00000627717
A0A0D9SFV9 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
183 aa
18.9 kDa
No 0
MEF2C-231
ENSP00000487311
ENST00000628656
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
417 aa
44.9 kDa
No 0
MEF2C-232
ENSP00000486554
ENST00000629612
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL6 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
465 aa
50.3 kDa
No 0
MEF2C-234
ENSP00000485972
ENST00000631026
A0A0D9SET2 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
205 aa
22.9 kDa
No 0
MEF2C-236
ENSP00000490525
ENST00000635898
A0A1B0GVI4 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0046983 [protein dimerization activity]
Show all
42 aa
5.1 kDa
No 0
MEF2C-239
ENSP00000490473
ENST00000636294
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL7 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_b
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
473 aa
51.2 kDa
No 0
MEF2C-243
ENSP00000489865
ENST00000636541
A0A1B0GTW4 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0007399 [nervous system development]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
123 aa
14.3 kDa
No 0
MEF2C-244
ENSP00000490630
ENST00000636998
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0
MEF2C-249
ENSP00000490354
ENST00000637481
A0A1B0GV32 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Show all
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0007399 [nervous system development]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
Show all
462 aa
50.1 kDa
No 0
MEF2C-254
ENSP00000490241
ENST00000637732
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000165 [MAPK cascade]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001228 [DNA-binding transcription activator activity, RNA polymerase II-specific]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002931 [response to ischemia]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [minor groove of adenine-thymine-rich DNA binding]
GO:0003700 [DNA-binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007275 [multicellular organism development]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016528 [sarcoplasm]
GO:0016607 [nuclear speck]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0032991 [protein-containing complex]
GO:0033613 [activating transcription factor binding]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0042100 [B cell proliferation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0098794 [postsynapse]
GO:1904706 [negative regulation of vascular associated smooth muscle cell proliferation]
GO:1904753 [negative regulation of vascular associated smooth muscle cell migration]
GO:1905563 [negative regulation of vascular endothelial cell proliferation]
GO:1990837 [sequence-specific double-stranded DNA binding]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of NMDA receptor activity]
GO:2000311 [regulation of AMPA receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0

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