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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:58.4 nTPM
HPA:58.4 nTPM
GTEx:25.3 nTPM
FANTOM5:216.8 Scaled Tags Per Million
Pig:50.2 nTPM
Mouse:42.6 nTPM
Allen mouse:2.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 58.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 48.2
2411 Female, age 72, unknown 58.1
1830 Male, age 51, unknown 55.6
1833 Male, age 53, unknown 53.1
1870 Female, age 42, unknown 51.6
2586 Male, age 75, left hemisphere 50.3
2019 Male, age 18, unknown 49.0
2828 Female, age 72, unknown 48.4
2219 Male, age 76, both hemispheres 42.6
1827 Male, age 72, unknown 37.5
2666 Male, age 74, left hemisphere 35.9
Dorsal raphe nucleus
nTPM: 40.4
2750 Male, age 76, both hemispheres 58.5
2016 Female, age 72, unknown 41.9
1828 Male, age 53, unknown 38.7
2047 Male, age 72, unknown 34.0
2298 Female, age 72, unknown 29.2
Inferior colliculus
nTPM: 40.4
1890 Male, age 53, unknown 43.8
1848 Female, age 42, unknown 40.5
2849 Male, age 72, unknown 39.3
2097 Female, age 72, unknown 38.0
Median raphe nucleus
nTPM: 31.5
2220 Male, age 76, midline 31.5
Pedunculopontine tegmental nucleus
nTPM: 39.2
2334 Male, age 80, both hemispheres 44.1
1921 Female, age 85, both hemispheres 39.9
2338 Male, age 61, both hemispheres 33.5
Periaquaductal grey, anterior
nTPM: 37.8
2502 Female, age 75, unknown 43.4
1947 Male, age 18, unknown 37.8
1795 Male, age 51, unknown 32.1
Periaquaductal grey, dorsal
nTPM: 31.6
2464 Female, age 72, unknown 44.6
1831 Male, age 72, unknown 28.6
1840 Male, age 53, unknown 27.9
2850 Male, age 76, both hemispheres 25.1
Periaquaductal grey, lateral
nTPM: 33.7
2272 Male, age 74, both hemispheres 38.5
2053 Male, age 18, unknown 34.5
2140 Male, age 76, both hemispheres 28.0
Pretectal area
nTPM: 38.5
2316 Male, age 76, right hemisphere 52.2
1815 Male, age 53, unknown 44.2
2007 Male, age 72, unknown 41.0
2667 Female, age 75, unknown 40.6
1817 Female, age 42, unknown 39.1
2407 Male, age 75, both hemispheres 38.9
2825 Male, age 18, unknown 37.9
2273 Male, age 74, both hemispheres 35.3
1944 Female, age 72, unknown 32.6
2224 Female, age 72, unknown 32.2
1816 Male, age 51, unknown 30.0
Red nucleus
nTPM: 58.4
2503 Female, age 72, unknown 66.4
2769 Male, age 72, unknown 66.0
1865 Male, age 51, unknown 65.3
2227 Male, age 72, unknown 65.2
1904 Male, age 53, unknown 64.7
2785 Male, age 18, unknown 62.2
2588 Male, age 74, left hemisphere 58.7
1954 Female, age 42, unknown 56.8
1821 Female, age 72, unknown 56.1
2823 Male, age 76, right hemisphere 55.3
2584 Male, age 75, left hemisphere 42.9
2725 Female, age 75, unknown 40.6
Substantia nigra
nTPM: 38.4
2583 Male, age 75, right hemisphere 45.6
2590 Female, age 75, unknown 45.1
2409 Female, age 72, unknown 43.7
1851 Male, age 51, unknown 41.9
1889 Female, age 72, unknown 40.6
2699 Male, age 18, unknown 40.0
1916 Female, age 42, unknown 32.5
1941 Male, age 53, unknown 32.3
2241 Male, age 72, unknown 31.6
2665 Male, age 74, both hemispheres 30.6
Superior colliculus
nTPM: 44.1
1913 Female, age 42, unknown 62.2
1995 Male, age 72, unknown 60.1
1895 Male, age 76, right hemisphere 50.2
1839 Male, age 51, unknown 44.2
2587 Male, age 74, left hemisphere 42.4
2668 Female, age 75, unknown 41.9
1796 Male, age 53, unknown 37.5
2261 Male, age 18, unknown 35.6
2664 Male, age 75, both hemispheres 34.4
2087 Female, age 72, unknown 32.6
Ventral tegmental area
nTPM: 41.0
2410 Female, age 72, unknown 51.6
2223 Female, age 72, unknown 43.6
1942 Male, age 51, unknown 40.3
2021 Male, age 53, unknown 39.1
1915 Female, age 42, unknown 37.1
2218 Male, age 76, both hemispheres 34.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 25.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 25.3
Samples: 139

Max nTPM: 69.8
Min nTPM: 9.7
Std nTPM: 8.6
Median nTPM: 24.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 69.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 52.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 48.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 46.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 45.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 40.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 40.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 39.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 39.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 37.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 37.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 35.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 35.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 35.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 34.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 33.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 32.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 32.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 32.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 31.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 31.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 31.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 30.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 30.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 30.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 30.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 30.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 29.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 29.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 28.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 28.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 28.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 27.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 27.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 27.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 27.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 27.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 27.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 27.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 27.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 26.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 26.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 26.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 26.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 26.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 26.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 26.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 26.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 26.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 26.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 26.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 25.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 25.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 25.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 25.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 24.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 24.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 24.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 24.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 24.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 24.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 24.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 24.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 24.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 24.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 24.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 23.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 23.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 23.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 23.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 23.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 23.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 23.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 23.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 22.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 22.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 22.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 22.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 22.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 22.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 22.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 21.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 21.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 21.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 21.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 21.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 21.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 21.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 21.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 21.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 20.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 20.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 20.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 20.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 20.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 20.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 20.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 20.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 19.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 19.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 19.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 19.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 18.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 18.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 18.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 18.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 18.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 17.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 17.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 17.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 17.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 16.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 16.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 16.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 16.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 15.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 15.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 15.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 14.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 14.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 14.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 14.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 13.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 12.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 12.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 12.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 12.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 9.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 216.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 216.8
FF:10158-103A5 76 years, female 216.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.2
Pig sample Sample description nTPM
Midbrain
nTPM: 50.2
Samples: 4

Max nTPM: 61.6
Min nTPM: 43.0
Sample A Female 61.6
Sample B Female 48.5
Sample C Male 47.7
Sample D Male 43.0
Periaqueductal gray
nTPM: 43.4
Samples: 3

Max nTPM: 50.8
Min nTPM: 37.1
Sample B Female 50.8
Sample C Male 37.1
Sample D Male 42.4
Substantia nigra
nTPM: 48.1
Samples: 4

Max nTPM: 67.9
Min nTPM: 35.0
Sample A Female 46.1
Sample B Female 35.0
Sample C Male 43.5
Sample D Male 67.9
Superior colliculi
nTPM: 43.8
Samples: 4

Max nTPM: 53.4
Min nTPM: 25.8
Sample A Female 48.8
Sample B Female 25.8
Sample C Male 47.0
Sample D Male 53.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 42.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 42.6
Samples: 4

Max nTPM: 44.3
Min nTPM: 38.5
Sample A Male 38.5
Sample B Male 43.9
Sample C Female 44.3
Sample D Female 43.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.6
70546366 Antisense, RP_050623_04_B08, Mouse strain C57BL/6J (56 days, male) 2.6

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