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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:54.2 nTPM
HPA:54.2 nTPM
GTEx:52.2 nTPM
FANTOM5:2.3 Scaled Tags Per Million
Pig:40.7 nTPM
Mouse:92.3 nTPM
Allen mouse:15.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 54.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 27.7
2666 Male, age 74, left hemisphere 71.4
2219 Male, age 76, both hemispheres 44.4
2411 Female, age 72, unknown 41.4
1827 Male, age 72, unknown 26.0
1870 Female, age 42, unknown 25.5
1833 Male, age 53, unknown 20.8
1830 Male, age 51, unknown 17.5
2828 Female, age 72, unknown 17.2
2586 Male, age 75, left hemisphere 12.8
2019 Male, age 18, unknown 0.0
Dorsal raphe nucleus
nTPM: 42.4
2298 Female, age 72, unknown 59.3
2047 Male, age 72, unknown 53.3
1828 Male, age 53, unknown 41.5
2750 Male, age 76, both hemispheres 38.3
2016 Female, age 72, unknown 19.4
Inferior colliculus
nTPM: 23.6
2097 Female, age 72, unknown 27.5
2849 Male, age 72, unknown 24.9
1848 Female, age 42, unknown 24.1
1890 Male, age 53, unknown 17.7
Median raphe nucleus
nTPM: 54.2
2220 Male, age 76, midline 54.2
Pedunculopontine tegmental nucleus
nTPM: 37.9
1921 Female, age 85, both hemispheres 62.5
2334 Male, age 80, both hemispheres 39.1
2338 Male, age 61, both hemispheres 12.2
Periaquaductal grey, anterior
nTPM: 49.6
1947 Male, age 18, unknown 63.8
2502 Female, age 75, unknown 46.5
1795 Male, age 51, unknown 38.6
Periaquaductal grey, dorsal
nTPM: 25.9
1840 Male, age 53, unknown 32.0
2850 Male, age 76, both hemispheres 25.0
1831 Male, age 72, unknown 24.0
2464 Female, age 72, unknown 22.7
Periaquaductal grey, lateral
nTPM: 19.2
2053 Male, age 18, unknown 26.3
2140 Male, age 76, both hemispheres 18.9
2272 Male, age 74, both hemispheres 12.2
Pretectal area
nTPM: 16.6
2224 Female, age 72, unknown 41.9
2825 Male, age 18, unknown 41.0
2667 Female, age 75, unknown 19.6
1816 Male, age 51, unknown 14.8
2007 Male, age 72, unknown 14.5
2316 Male, age 76, right hemisphere 14.2
2407 Male, age 75, both hemispheres 9.0
1815 Male, age 53, unknown 8.7
1944 Female, age 72, unknown 8.6
2273 Male, age 74, both hemispheres 6.6
1817 Female, age 42, unknown 3.5
Red nucleus
nTPM: 9.9
1821 Female, age 72, unknown 19.0
2227 Male, age 72, unknown 16.8
2769 Male, age 72, unknown 16.5
1954 Female, age 42, unknown 12.9
2584 Male, age 75, left hemisphere 12.3
2823 Male, age 76, right hemisphere 11.0
1904 Male, age 53, unknown 9.7
1865 Male, age 51, unknown 7.1
2503 Female, age 72, unknown 7.0
2588 Male, age 74, left hemisphere 5.7
2725 Female, age 75, unknown 1.3
2785 Male, age 18, unknown 0.0
Substantia nigra
nTPM: 42.8
1916 Female, age 42, unknown 94.0
1851 Male, age 51, unknown 52.9
2241 Male, age 72, unknown 52.8
2699 Male, age 18, unknown 52.8
2665 Male, age 74, both hemispheres 50.7
1941 Male, age 53, unknown 47.0
2409 Female, age 72, unknown 34.4
1889 Female, age 72, unknown 25.9
2583 Male, age 75, right hemisphere 9.6
2590 Female, age 75, unknown 7.7
Superior colliculus
nTPM: 21.0
2668 Female, age 75, unknown 77.6
2261 Male, age 18, unknown 26.9
1895 Male, age 76, right hemisphere 24.6
1796 Male, age 53, unknown 23.4
1839 Male, age 51, unknown 20.5
2664 Male, age 75, both hemispheres 18.3
2587 Male, age 74, left hemisphere 12.4
2087 Female, age 72, unknown 6.0
1913 Female, age 42, unknown 0.0
1995 Male, age 72, unknown 0.0
Ventral tegmental area
nTPM: 42.1
1915 Female, age 42, unknown 60.6
2218 Male, age 76, both hemispheres 55.8
2410 Female, age 72, unknown 50.9
1942 Male, age 51, unknown 37.0
2021 Male, age 53, unknown 30.2
2223 Female, age 72, unknown 18.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 52.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 52.2
Samples: 139

Max nTPM: 231.0
Min nTPM: 2.2
Std nTPM: 49.9
Median nTPM: 34.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 231.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 193.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 188.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 179.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 173.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 170.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 163.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 160.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 151.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 137.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 137.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 131.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 129.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 127.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 126.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 124.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 118.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 116.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 107.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 104.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 103.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 103.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 101.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 98.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 97.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 89.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 84.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 84.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 84.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 83.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 81.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 80.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 79.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 79.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 75.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 75.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 74.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 74.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 73.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 73.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 73.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 72.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 71.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 67.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 63.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 62.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 62.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 60.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 56.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 56.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 54.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 53.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 53.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 53.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 52.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 51.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 51.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 45.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 39.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 38.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 35.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 35.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 34.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 33.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 33.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 30.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 28.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 26.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 26.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 24.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 23.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 23.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 23.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 23.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 23.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 23.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 21.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 20.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 17.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 17.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 17.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 17.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 16.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 15.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 15.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 15.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 15.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 14.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 14.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 14.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 13.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 13.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 13.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 12.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 12.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 10.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 9.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 9.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 9.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 9.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 9.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 8.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 8.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 8.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 7.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 6.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 6.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 6.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 5.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 5.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 5.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 4.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 4.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 4.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 4.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 4.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 2.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2.3
FF:10158-103A5 76 years, female 2.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 40.7
Pig sample Sample description nTPM
Midbrain
nTPM: 36.1
Samples: 4

Max nTPM: 81.3
Min nTPM: 4.5
Sample A Female 4.5
Sample B Female 23.6
Sample C Male 81.3
Sample D Male 34.9
Periaqueductal gray
nTPM: 25.7
Samples: 3

Max nTPM: 39.4
Min nTPM: 18.7
Sample B Female 19.1
Sample C Male 39.4
Sample D Male 18.7
Substantia nigra
nTPM: 40.7
Samples: 4

Max nTPM: 68.1
Min nTPM: 5.6
Sample A Female 62.4
Sample B Female 26.8
Sample C Male 68.1
Sample D Male 5.6
Superior colliculi
nTPM: 25.8
Samples: 4

Max nTPM: 39.0
Min nTPM: 10.9
Sample A Female 28.3
Sample B Female 10.9
Sample C Male 39.0
Sample D Male 24.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 92.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 92.3
Samples: 4

Max nTPM: 100.2
Min nTPM: 80.6
Sample A Male 97.6
Sample B Male 90.9
Sample C Female 80.6
Sample D Female 100.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.4
68924841 Antisense, RP_050309_01_B04, Mouse strain C57BL/6J (56 days, male) 15.4
70301082 Antisense, RP_050309_01_B04, Mouse strain C57BL/6J (56 days, male) 11.8

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