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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 44.2
Min nTPM: 12.9
Std nTPM: 6.5
Median nTPM:
414_1
84 years, female
44.2
495_1
57 years, female
44.2
308_1
70 years, female
43.7
466_1
57 years, female
43.3
413_1
59 years, female
40.8
307_1
66 years, female
38.0
415_1
77 years, female
37.2
490_1
67 years, female
32.2
347_1
72 years, male
30.5
491_1
89 years, female
30.2
319_1
81 years, male
28.7
229_1
69 years, female
28.2
246_1
77 years, male
28.1
266_1
85 years, male
28.0
163_1
78 years, male
27.9
384_1
83 years, male
27.3
322_1
76 years, male
27.2
177_1
74 years, male
27.1
2_1
77 years, female
26.7
316_1
62 years, male
26.2
89_1
63 years, male
26.1
501_1
88 years, male
26.1
355_1
70 years, female
25.6
43_1
64 years, female
25.5
6_1
73 years, female
25.4
32_1
67 years, male
25.4
292_1
71 years, male
25.4
354_1
81 years, female
25.4
389_1
86 years, female
25.3
149_1
88 years, male
25.2
350_1
84 years, female
25.2
117_1
61 years, male
25.1
324_1
76 years, male
24.8
321_1
62 years, female
24.0
468_1
89 years, male
24.0
99_1
64 years, male
23.7
315_1
62 years, female
23.5
377_1
82 years, female
23.5
526_1
61 years, male
23.4
17_1
71 years, male
23.3
313_1
79 years, female
23.2
172_1
72 years, female
22.8
405_1
91 years, male
22.8
376_1
75 years, female
22.7
119_1
70 years, female
22.5
81_1
67 years, male
22.3
265_1
87 years, male
22.3
311_1
78 years, male
22.3
217_1
76 years, male
22.2
291_1
76 years, male
22.2
386_1
76 years, male
21.9
352_1
62 years, male
21.8
318_1
68 years, male
21.7
293_1
68 years, female
21.3
153_1
70 years, female
21.2
379_1
60 years, male
21.1
314_1
67 years, male
20.7
126_1
63 years, male
20.6
286_1
68 years, female
20.6
353_1
82 years, female
20.6
499_1
55 years, female
20.5
42_1
85 years, male
20.3
356_1
87 years, female
20.3
375_1
74 years, female
20.3
349_1
83 years, male
20.0
425_1
59 years, female
20.0
137_1
83 years, male
19.9
251_1
78 years, male
19.7
243_1
75 years, male
19.6
351_1
91 years, male
19.6
447_1
81 years, male
19.6
18_1
88 years, male
19.5
394_1
75 years, female
19.3
9_1
66 years, female
19.2
162_1
79 years, female
19.1
406_1
79 years, male
19.1
189_1
76 years, male
18.9
139_1
64 years, female
18.4
348_1
84 years, male
18.4
218_1
71 years, female
18.3
115_1
83 years, male
18.1
120_1
70 years, female
17.9
142_1
61 years, female
17.9
288_1
66 years, female
17.5
320_1
89 years, female
17.5
35_1
74 years, female
17.4
173_1
67 years, male
17.4
335_1
73 years, female
17.4
503_1
68 years, male
17.3
41_1
94 years, female
17.2
295_1
61 years, female
17.1
404_1
82 years, female
16.8
317_1
60 years, male
16.7
517_1
88 years, male
16.6
480_1
63 years, male
16.0
396_1
62 years, male
15.8
518_1
75 years, female
15.8
237_1
82 years, male
15.6
4_1
88 years, female
15.2
254_1
77 years, female
14.6
452_1
88 years, female
14.3
109_1
81 years, female
13.8
145_1
84 years, male
13.8
506_1
65 years, male
13.4
264_1
73 years, female
12.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
