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TISSUE PRIMARY DATA KIDNEY Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN NASOPHARYNX ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
ANTIBODIES
AND
VALIDATION
Dictionary
Kidney
Tissue proteome
Kidney
KIDNEY - Expression summary
Protein expression
Kidneyi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
h
m
l
n
Bowman's capsule: Not detected
Cells in glomeruli: Not detected
Collecting ducts: Not detected
Distal tubules: Not detected
Proximal tubules (cell body): Not detected
Proximal tubules (microvilli): High
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Microvilli staining in proximal tubules.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:844.8 nTPM
HPA:844.8 nTPM
GTEx:350.4 nTPM
FANTOM5:282.6 Scaled Tags Per Million

KIDNEY - Multiplex stainingi

Antibody localization in the annotated cell types/states of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state-specific markers, and subcellular location. The scores are based on multiplex immunohistochemistry profiling in selected tissues.

Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity, while additional locations are characterized by lower overlap and weaker antibody signal intensity.

The antibody of interest is reported in green, while cell types/states are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.

Read more
- Antibody HPA056027
Main location Proximal tubules
No antibody overlap
Antibody overlap>75%
LocationMicrovilli
No antibody overlap
No antibody overlap
No antibody overlap

KIDNEY - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Read more
Antibody HPA045046Antibody HPA056027
Bowman's capsule -Not detected
Cells in glomeruli Not detectedNot detected
Cells in tubules High-
Collecting ducts -Not detected
Distal tubules -Not detected
Proximal tubules (cell body) -Not detected
Proximal tubules (microvilli) -High





KIDNEY - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Read more
Average nTPM 844.8
overview
Female, age 58
Kidney sample 55
nTPM: 722.6
Cell types%
Cells in tubules:
60

Cells in glomeruli:
20

Fibroblasts:
5

Other cell types:
15

overview
Female, age 67
Kidney sample 56
nTPM: 688.4
Cell types%
Cells in tubules:
70

Cells in glomeruli:
15

Fibroblasts:
10

Other cell types:
5

overview
Female, age 55
Kidney sample 57
nTPM: 226.4
Cell types%
Cells in tubules:
80

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
5

overview
Male, age 46
Kidney sample 58
nTPM: 825.3
Cell types%
Cells in tubules:
60

Cells in glomeruli:
25

Fibroblasts:
5

Other cell types:
10

overview
Female, age 57
Kidney sample 358
nTPM: 698
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Male, age 78
Kidney sample 377
nTPM: 602.2
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
20

overview
Male, age 73
Kidney sample 380
nTPM: 2502
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Female, age 59
Kidney sample 394
nTPM: 762.6
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
15

overview
Female, age 48
Kidney sample 414
nTPM: 576
Cell types%
Cells in tubules:
60

Cells in glomeruli:
5

Fibroblasts:
10

Other cell types:
25


KIDNEY - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 350.4
GTEx sample id Sample description nTPM
Kidney - Cortex
Average nTPM: 350.4
Samples: 85

Max nTPM: 1077.9
Min nTPM: 22.6
Std nTPM: 215.5
Median nTPM: 341.6
GTEX-1NV8Z-2226-SM-EXOJ2 60-69 years, male 1077.9
GTEX-T6MN-1826-SM-EXOHN 50-59 years, male 887.1
GTEX-Y5V5-1226-SM-EYYVP 60-69 years, female 837.8
GTEX-T5JC-1526-SM-4DM68 20-29 years, male 781.9
GTEX-13NYB-1726-SM-5N9G2 40-49 years, male 758.1
GTEX-13OW6-1826-SM-5N9F9 50-59 years, male 698.9
GTEX-1BAJH-1826-SM-731DA 70-79 years, male 657.2
GTEX-QDT8-1726-SM-EYYV6 30-39 years, female 656.7
GTEX-14E6D-2526-SM-5YYA9 50-59 years, male 626.5
GTEX-1JMQJ-1726-SM-E9U4V 50-59 years, male 598.9
GTEX-1H3NZ-2126-SM-9WPQ6 60-69 years, male 591.9
GTEX-Y5V6-2026-SM-5IFHO 60-69 years, male 588.5
GTEX-16MT8-1926-SM-7EPGL 60-69 years, female 578.6
GTEX-QDVN-1626-SM-48TZC 50-59 years, male 564.4
GTEX-ZC5H-1726-SM-5HL7X 40-49 years, female 564.4
GTEX-1GF9W-1326-SM-7P8PX 60-69 years, male 552.0
GTEX-1GMR3-2426-SM-7MXV2 40-49 years, male 540.4
GTEX-1KWVE-0826-SM-CXZKO 30-39 years, male 514.5
GTEX-1R9PO-1626-SM-E6CPT 60-69 years, female 499.3
GTEX-1I1GP-1926-SM-CNNQU 50-59 years, male 460.4
GTEX-1HBPI-2026-SM-CE6RZ 50-59 years, male 448.9
GTEX-P4QS-1126-SM-3NMD5 60-69 years, male 446.7
GTEX-15DYW-2026-SM-6AJBD 60-69 years, female 445.7
GTEX-11OF3-1326-SM-5N9FJ 60-69 years, male 445.3
GTEX-1E2YA-1626-SM-7MGXS 50-59 years, male 442.0
GTEX-1GF9V-1926-SM-9JGHE 60-69 years, male 440.6
GTEX-13O1R-2526-SM-5N9FW 60-69 years, male 434.3
GTEX-15CHQ-2126-SM-6871M 60-69 years, male 427.5
GTEX-1JJ6O-2526-SM-AHZ3J 60-69 years, male 423.3
GTEX-1JMLX-1526-SM-AHZ3N 50-59 years, male 411.0
GTEX-REY6-1826-SM-EAZAT 60-69 years, male 410.3
GTEX-12WSG-0826-SM-5EQ5A 50-59 years, female 398.6
GTEX-17HHY-2326-SM-7KFSR 50-59 years, male 397.6
GTEX-14C5O-2026-SM-5YYB1 60-69 years, male 396.1
GTEX-1IKK5-0926-SM-A9G2U 60-69 years, male 390.0
GTEX-1HB9E-1826-SM-D4P33 50-59 years, male 381.8
GTEX-17F96-1926-SM-7MGWY 70-79 years, male 380.3
GTEX-145MN-0326-SM-5QGQI 30-39 years, male 373.8
GTEX-1EKGG-2226-SM-7IGOA 60-69 years, male 371.8
GTEX-1IL2V-1826-SM-ARU7R 70-79 years, male 370.2
GTEX-1GTWX-1826-SM-9QEHG 60-69 years, male 356.2
GTEX-1PWST-2226-SM-EVR3G 70-79 years, male 353.6
GTEX-1GN1U-2126-SM-AHZ4J 50-59 years, female 341.6
GTEX-1A8FM-2026-SM-7P8RN 50-59 years, female 341.5
GTEX-1497J-0826-SM-5NQAJ 60-69 years, male 334.1
GTEX-1J1OQ-1426-SM-AHZ3P 40-49 years, female 332.4
GTEX-1JMPZ-1226-SM-ARU8Y 30-39 years, male 327.7
GTEX-1QP6S-1526-SM-EXUSG 40-49 years, male 315.8
GTEX-1C6VQ-2326-SM-7IGN1 50-59 years, male 289.6
GTEX-13RTJ-2226-SM-5S2Q1 60-69 years, male 276.4
GTEX-XPVG-0526-SM-4B65N 50-59 years, male 276.0
GTEX-1HCU7-1826-SM-A9G2A 50-59 years, male 271.2
GTEX-1K9T9-1826-SM-CXZK2 50-59 years, female 249.7
GTEX-14C39-2126-SM-664OH 40-49 years, male 247.6
GTEX-11GS4-2326-SM-5A5KS 60-69 years, male 242.5
GTEX-S33H-1426-SM-EZ6L7 30-39 years, male 232.2
GTEX-1LG7Y-2726-SM-D5OVW 50-59 years, male 231.0
GTEX-1N2EF-1426-SM-EXUSH 60-69 years, male 229.9
GTEX-ZDXO-0226-SM-4WKH7 60-69 years, male 227.5
GTEX-O5YV-1226-SM-EV795 60-69 years, female 225.4
GTEX-1JMQK-1926-SM-CJI3B 60-69 years, male 197.2
GTEX-13OVI-1126-SM-5KLZF 60-69 years, female 181.4
GTEX-1F48J-2226-SM-7MXTN 50-59 years, female 173.8
GTEX-ZLFU-0926-SM-5P9F8 40-49 years, male 165.8
GTEX-ZVZP-0926-SM-5GIDB 50-59 years, male 162.9
GTEX-147F4-2626-SM-5Q5CS 50-59 years, male 159.7
GTEX-1MUQO-2526-SM-E9TJN 60-69 years, male 150.0
GTEX-ZYFG-1626-SM-5GZYY 60-69 years, female 140.5
GTEX-1AX8Z-2326-SM-731CR 60-69 years, male 137.7
GTEX-17F97-1926-SM-7IGM4 50-59 years, male 136.5
GTEX-1399S-0526-SM-5IJG8 30-39 years, female 130.7
GTEX-1CB4J-1926-SM-7MGX8 60-69 years, male 123.5
GTEX-1H3VY-1926-SM-9JGHJ 50-59 years, male 119.9
GTEX-1N2DW-1826-SM-EAZ54 50-59 years, male 116.7
GTEX-ZYT6-2226-SM-5GIC9 30-39 years, male 107.0
GTEX-NPJ8-2226-SM-3TW8D 40-49 years, male 106.8
GTEX-11TTK-1926-SM-5PNW8 60-69 years, female 89.3
GTEX-13OVL-1826-SM-5KLZR 50-59 years, male 85.7
GTEX-QLQW-1626-SM-CMKFE 30-39 years, male 78.3
GTEX-1A3MW-2226-SM-73KUX 60-69 years, female 57.8
GTEX-13112-2126-SM-5GCO4 50-59 years, male 51.8
GTEX-12696-0926-SM-5FQTV 60-69 years, male 46.6
GTEX-RN64-1626-SM-48FD7 50-59 years, male 43.3
GTEX-ZE9C-1426-SM-4WKGM 60-69 years, male 24.7
GTEX-1OJC4-2326-SM-DTXA5 50-59 years, female 22.6
Show allShow less
Kidney - Medulla
Average nTPM: 146.7
Samples: 4

Max nTPM: 354.1
Min nTPM: 40.1
Std nTPM: 127.2
Median nTPM: 96.3
GTEX-RU72-1926-SM-EAZ3F 50-59 years, female 354.1
GTEX-TKQ2-0626-SM-EZ6LB 50-59 years, male 147.8
GTEX-T5JC-1626-SM-EZ6KW 20-29 years, male 44.9
GTEX-R55E-2026-SM-EZ6L1 20-29 years, male 40.1

KIDNEY - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 282.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Kidney
Scaled Tags Per Million: 282.6
FF:10017-101C8 60,62,63 years, female 282.6

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