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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 174.5
Min nTPM: 46.2
Std nTPM: 19.7
Median nTPM:
490_1
67 years, female
174.5
491_1
89 years, female
148.0
413_1
59 years, female
137.5
313_1
79 years, female
125.2
415_1
77 years, female
123.9
414_1
84 years, female
119.9
466_1
57 years, female
115.8
162_1
79 years, female
111.9
315_1
62 years, female
105.1
149_1
88 years, male
104.7
142_1
61 years, female
103.8
42_1
85 years, male
103.7
117_1
61 years, male
103.2
501_1
88 years, male
102.8
89_1
63 years, male
101.9
126_1
63 years, male
100.0
32_1
67 years, male
94.8
324_1
76 years, male
94.8
495_1
57 years, female
94.7
35_1
74 years, female
94.4
468_1
89 years, male
93.5
217_1
76 years, male
92.9
81_1
67 years, male
92.8
2_1
77 years, female
91.1
375_1
74 years, female
90.8
347_1
72 years, male
90.4
266_1
85 years, male
90.3
119_1
70 years, female
90.2
499_1
55 years, female
90.2
145_1
84 years, male
88.9
139_1
64 years, female
88.5
396_1
62 years, male
88.4
4_1
88 years, female
87.9
526_1
61 years, male
87.7
265_1
87 years, male
87.6
307_1
66 years, female
86.5
109_1
81 years, female
85.8
447_1
81 years, male
85.7
99_1
64 years, male
85.3
43_1
64 years, female
85.1
115_1
83 years, male
85.0
319_1
81 years, male
84.5
9_1
66 years, female
84.3
153_1
70 years, female
83.5
120_1
70 years, female
82.6
518_1
75 years, female
82.5
246_1
77 years, male
82.1
316_1
62 years, male
82.0
237_1
82 years, male
81.8
137_1
83 years, male
81.6
229_1
69 years, female
80.7
17_1
71 years, male
80.6
254_1
77 years, female
80.3
389_1
86 years, female
79.2
18_1
88 years, male
79.0
243_1
75 years, male
77.5
311_1
78 years, male
77.4
314_1
67 years, male
77.3
386_1
76 years, male
75.9
480_1
63 years, male
75.9
379_1
60 years, male
75.1
264_1
73 years, female
74.4
506_1
65 years, male
73.3
6_1
73 years, female
72.7
351_1
91 years, male
72.2
321_1
62 years, female
72.1
404_1
82 years, female
71.9
517_1
88 years, male
71.9
308_1
70 years, female
71.7
503_1
68 years, male
70.9
288_1
66 years, female
70.7
335_1
73 years, female
70.7
352_1
62 years, male
70.6
376_1
75 years, female
70.4
405_1
91 years, male
70.4
320_1
89 years, female
69.8
189_1
76 years, male
69.4
41_1
94 years, female
69.2
173_1
67 years, male
68.9
425_1
59 years, female
68.8
377_1
82 years, female
68.4
354_1
81 years, female
68.1
452_1
88 years, female
67.9
394_1
75 years, female
67.6
356_1
87 years, female
67.2
349_1
83 years, male
66.7
293_1
68 years, female
65.9
355_1
70 years, female
65.6
384_1
83 years, male
64.9
251_1
78 years, male
64.4
292_1
71 years, male
64.3
172_1
72 years, female
63.8
406_1
79 years, male
63.4
286_1
68 years, female
63.3
322_1
76 years, male
63.0
350_1
84 years, female
63.0
348_1
84 years, male
62.8
218_1
71 years, female
61.6
317_1
60 years, male
61.3
318_1
68 years, male
60.2
291_1
76 years, male
58.3
295_1
61 years, female
57.9
353_1
82 years, female
54.7
177_1
74 years, male
53.0
163_1
78 years, male
46.2
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
