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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:58.3 nTPM
HPA:58.3 nTPM
GTEx:57.1 nTPM
FANTOM5:100.6 Scaled Tags Per Million
Pig:42.6 nTPM
Mouse:55.1 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 58.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 54.6
2019 Male, age 18, unknown 56.6
1827 Male, age 72, unknown 55.8
2828 Female, age 72, unknown 55.6
2411 Female, age 72, unknown 55.2
2219 Male, age 76, both hemispheres 55.1
1870 Female, age 42, unknown 54.8
1833 Male, age 53, unknown 54.4
2666 Male, age 74, left hemisphere 53.9
1830 Male, age 51, unknown 53.5
2586 Male, age 75, left hemisphere 50.9
Dorsal raphe nucleus
nTPM: 55.0
2298 Female, age 72, unknown 57.3
1828 Male, age 53, unknown 55.9
2750 Male, age 76, both hemispheres 54.7
2047 Male, age 72, unknown 54.3
2016 Female, age 72, unknown 52.8
Inferior colliculus
nTPM: 53.7
2097 Female, age 72, unknown 55.6
1848 Female, age 42, unknown 53.6
1890 Male, age 53, unknown 53.5
2849 Male, age 72, unknown 52.0
Median raphe nucleus
nTPM: 56.8
2220 Male, age 76, midline 56.8
Pedunculopontine tegmental nucleus
nTPM: 56.6
2338 Male, age 61, both hemispheres 57.9
2334 Male, age 80, both hemispheres 57.7
1921 Female, age 85, both hemispheres 54.2
Periaquaductal grey, anterior
nTPM: 54.0
2502 Female, age 75, unknown 54.5
1947 Male, age 18, unknown 53.9
1795 Male, age 51, unknown 53.6
Periaquaductal grey, dorsal
nTPM: 53.9
2850 Male, age 76, both hemispheres 55.9
1831 Male, age 72, unknown 55.7
1840 Male, age 53, unknown 52.8
2464 Female, age 72, unknown 51.4
Periaquaductal grey, lateral
nTPM: 53.9
2272 Male, age 74, both hemispheres 55.3
2053 Male, age 18, unknown 53.6
2140 Male, age 76, both hemispheres 52.6
Pretectal area
nTPM: 57.3
2273 Male, age 74, both hemispheres 60.3
1817 Female, age 42, unknown 60.2
1816 Male, age 51, unknown 59.9
2667 Female, age 75, unknown 58.7
1815 Male, age 53, unknown 58.3
1944 Female, age 72, unknown 58.3
2007 Male, age 72, unknown 57.7
2224 Female, age 72, unknown 55.6
2407 Male, age 75, both hemispheres 55.2
2316 Male, age 76, right hemisphere 53.4
2825 Male, age 18, unknown 52.2
Red nucleus
nTPM: 55.8
1821 Female, age 72, unknown 59.0
2725 Female, age 75, unknown 58.9
2785 Male, age 18, unknown 57.3
1904 Male, age 53, unknown 56.6
2503 Female, age 72, unknown 56.5
1865 Male, age 51, unknown 56.2
1954 Female, age 42, unknown 56.2
2823 Male, age 76, right hemisphere 55.3
2588 Male, age 74, left hemisphere 55.0
2769 Male, age 72, unknown 53.4
2227 Male, age 72, unknown 53.3
2584 Male, age 75, left hemisphere 51.4
Substantia nigra
nTPM: 58.3
1916 Female, age 42, unknown 63.4
1851 Male, age 51, unknown 61.1
2241 Male, age 72, unknown 60.1
1889 Female, age 72, unknown 59.8
2699 Male, age 18, unknown 59.1
1941 Male, age 53, unknown 58.5
2409 Female, age 72, unknown 57.8
2665 Male, age 74, both hemispheres 55.0
2583 Male, age 75, right hemisphere 54.1
2590 Female, age 75, unknown 53.8
Superior colliculus
nTPM: 54.2
1913 Female, age 42, unknown 56.4
1995 Male, age 72, unknown 55.9
2261 Male, age 18, unknown 55.1
1796 Male, age 53, unknown 54.8
2087 Female, age 72, unknown 54.8
2587 Male, age 74, left hemisphere 54.8
1895 Male, age 76, right hemisphere 54.4
2668 Female, age 75, unknown 53.5
1839 Male, age 51, unknown 53.0
2664 Male, age 75, both hemispheres 49.7
Ventral tegmental area
nTPM: 56.8
1915 Female, age 42, unknown 59.9
2410 Female, age 72, unknown 59.8
2218 Male, age 76, both hemispheres 58.0
2223 Female, age 72, unknown 55.2
2021 Male, age 53, unknown 54.1
1942 Male, age 51, unknown 53.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 57.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 57.1
Samples: 139

Max nTPM: 85.5
Min nTPM: 37.1
Std nTPM: 9.5
Median nTPM: 57.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 85.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 79.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 75.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 75.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 74.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 73.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 73.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 73.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 72.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 71.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 71.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 71.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 70.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 69.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 69.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 69.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 69.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 68.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 68.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 68.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 67.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 67.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 66.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 66.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 66.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 65.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 65.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 65.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 65.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 64.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 64.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 64.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 64.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 64.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 63.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 62.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 62.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 62.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 62.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 61.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 61.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 61.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 61.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 61.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 61.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 61.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 60.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 60.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 60.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 60.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 60.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 59.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 59.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 59.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 59.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 59.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 58.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 58.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 58.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 58.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 58.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 57.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 57.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 57.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 57.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 57.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 57.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 57.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 57.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 56.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 56.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 56.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 56.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 56.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 56.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 56.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 55.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 55.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 54.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 53.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 53.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 53.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 53.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 52.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 52.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 52.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 52.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 52.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 51.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 51.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 51.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 51.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 50.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 50.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 50.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 50.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 49.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 49.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 49.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 48.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 48.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 48.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 48.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 48.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 46.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 46.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 46.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 46.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 46.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 46.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 45.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 45.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 44.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 44.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 43.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 43.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 43.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 42.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 41.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 41.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 41.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 41.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 41.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 41.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 37.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 100.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 100.6
FF:10158-103A5 76 years, female 100.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 42.6
Pig sample Sample description nTPM
Midbrain
nTPM: 40.9
Samples: 4

Max nTPM: 51.0
Min nTPM: 32.0
Sample A Female 51.0
Sample B Female 32.0
Sample C Male 44.0
Sample D Male 36.7
Periaqueductal gray
nTPM: 31.2
Samples: 3

Max nTPM: 34.6
Min nTPM: 29.3
Sample B Female 29.7
Sample C Male 34.6
Sample D Male 29.3
Substantia nigra
nTPM: 37.9
Samples: 4

Max nTPM: 48.2
Min nTPM: 30.7
Sample A Female 48.2
Sample B Female 32.4
Sample C Male 40.4
Sample D Male 30.7
Superior colliculi
nTPM: 42.6
Samples: 4

Max nTPM: 50.0
Min nTPM: 35.4
Sample A Female 47.5
Sample B Female 35.4
Sample C Male 50.0
Sample D Male 37.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 55.1
Samples: 4

Max nTPM: 57.3
Min nTPM: 51.4
Sample A Male 55.6
Sample B Male 57.3
Sample C Female 51.4
Sample D Female 56.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
69526749 Antisense, RP_050421_01_E09, Mouse strain C57BL/6J (56 days, male) 0.4

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