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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:52.5 nTPM
HPA:52.5 nTPM
GTEx:60.4 nTPM
FANTOM5:67.3 Scaled Tags Per Million
Pig:96.9 nTPM
Mouse:30.3 nTPM
Allen mouse:1.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 52.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.1
1870 Female, age 42, unknown 46.6
2666 Male, age 74, left hemisphere 45.2
1833 Male, age 53, unknown 44.7
2828 Female, age 72, unknown 44.4
2411 Female, age 72, unknown 43.9
1830 Male, age 51, unknown 43.4
2019 Male, age 18, unknown 42.0
2586 Male, age 75, left hemisphere 41.0
1827 Male, age 72, unknown 40.9
2219 Male, age 76, both hemispheres 38.8
Dorsal raphe nucleus
nTPM: 46.2
2016 Female, age 72, unknown 48.5
1828 Male, age 53, unknown 47.9
2047 Male, age 72, unknown 46.9
2298 Female, age 72, unknown 44.1
2750 Male, age 76, both hemispheres 43.5
Inferior colliculus
nTPM: 42.8
1848 Female, age 42, unknown 45.4
1890 Male, age 53, unknown 44.1
2849 Male, age 72, unknown 41.3
2097 Female, age 72, unknown 40.2
Median raphe nucleus
nTPM: 42.1
2220 Male, age 76, midline 42.1
Pedunculopontine tegmental nucleus
nTPM: 43.5
2334 Male, age 80, both hemispheres 45.7
2338 Male, age 61, both hemispheres 42.5
1921 Female, age 85, both hemispheres 42.2
Periaquaductal grey, anterior
nTPM: 44.0
1947 Male, age 18, unknown 47.3
2502 Female, age 75, unknown 45.9
1795 Male, age 51, unknown 38.8
Periaquaductal grey, dorsal
nTPM: 44.4
2850 Male, age 76, both hemispheres 48.5
1840 Male, age 53, unknown 44.2
2464 Female, age 72, unknown 42.5
1831 Male, age 72, unknown 42.4
Periaquaductal grey, lateral
nTPM: 41.3
2140 Male, age 76, both hemispheres 46.3
2053 Male, age 18, unknown 41.6
2272 Male, age 74, both hemispheres 36.2
Pretectal area
nTPM: 41.8
2667 Female, age 75, unknown 45.9
2316 Male, age 76, right hemisphere 44.7
2224 Female, age 72, unknown 43.3
2825 Male, age 18, unknown 43.2
1817 Female, age 42, unknown 42.3
1815 Male, age 53, unknown 41.9
1944 Female, age 72, unknown 41.7
2407 Male, age 75, both hemispheres 40.3
2273 Male, age 74, both hemispheres 39.8
1816 Male, age 51, unknown 38.6
2007 Male, age 72, unknown 38.3
Red nucleus
nTPM: 45.9
1821 Female, age 72, unknown 53.1
1954 Female, age 42, unknown 49.0
1904 Male, age 53, unknown 48.2
2503 Female, age 72, unknown 47.7
1865 Male, age 51, unknown 47.2
2227 Male, age 72, unknown 47.2
2769 Male, age 72, unknown 46.6
2823 Male, age 76, right hemisphere 46.3
2725 Female, age 75, unknown 43.4
2588 Male, age 74, left hemisphere 43.2
2785 Male, age 18, unknown 39.9
2584 Male, age 75, left hemisphere 38.9
Substantia nigra
nTPM: 52.5
1916 Female, age 42, unknown 63.9
2699 Male, age 18, unknown 63.5
1851 Male, age 51, unknown 59.3
2241 Male, age 72, unknown 57.1
2665 Male, age 74, both hemispheres 49.6
2590 Female, age 75, unknown 48.0
2409 Female, age 72, unknown 47.7
1941 Male, age 53, unknown 46.0
1889 Female, age 72, unknown 45.9
2583 Male, age 75, right hemisphere 43.7
Superior colliculus
nTPM: 41.5
1995 Male, age 72, unknown 44.0
1839 Male, age 51, unknown 43.9
2587 Male, age 74, left hemisphere 43.2
2664 Male, age 75, both hemispheres 42.9
1895 Male, age 76, right hemisphere 42.6
1913 Female, age 42, unknown 41.6
2668 Female, age 75, unknown 40.8
1796 Male, age 53, unknown 40.4
2087 Female, age 72, unknown 40.2
2261 Male, age 18, unknown 35.8
Ventral tegmental area
nTPM: 48.1
1915 Female, age 42, unknown 52.4
2410 Female, age 72, unknown 51.1
1942 Male, age 51, unknown 47.1
2021 Male, age 53, unknown 46.8
2218 Male, age 76, both hemispheres 46.5
2223 Female, age 72, unknown 44.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 60.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 60.4
Samples: 139

Max nTPM: 117.9
Min nTPM: 17.0
Std nTPM: 16.8
Median nTPM: 58.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 117.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 99.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 95.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 94.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 93.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 92.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 92.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 91.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 91.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 90.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 86.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 86.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 86.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 86.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 85.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 85.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 84.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 81.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 80.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 78.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 77.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 77.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 77.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 76.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 74.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 74.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 74.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 73.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 73.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 72.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 71.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 71.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 71.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 70.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 69.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 68.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 68.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 68.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 68.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 68.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 68.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 66.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 66.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 66.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 65.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 65.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 63.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 63.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 62.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 62.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 62.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 62.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 62.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 62.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 61.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 61.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 60.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 60.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 60.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 60.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 59.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 58.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 58.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 58.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 58.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 58.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 58.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 58.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 57.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 57.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 56.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 55.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 54.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 54.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 54.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 54.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 53.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 53.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 53.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 53.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 52.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 52.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 52.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 51.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 51.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 51.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 51.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 50.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 50.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 50.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 50.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 49.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 49.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 49.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 48.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 47.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 46.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 46.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 46.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 46.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 44.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 44.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 43.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 43.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 43.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 43.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 41.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 41.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 40.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 40.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 39.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 39.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 38.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 38.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 38.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 38.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 38.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 36.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 35.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 28.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 25.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 17.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 67.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 67.3
FF:10158-103A5 76 years, female 67.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 96.9
Pig sample Sample description nTPM
Midbrain
nTPM: 96.9
Samples: 4

Max nTPM: 117.3
Min nTPM: 70.8
Sample A Female 117.3
Sample B Female 98.3
Sample C Male 101.3
Sample D Male 70.8
Periaqueductal gray
nTPM: 79.7
Samples: 3

Max nTPM: 86.2
Min nTPM: 71.7
Sample B Female 86.2
Sample C Male 81.2
Sample D Male 71.7
Substantia nigra
nTPM: 88.5
Samples: 4

Max nTPM: 99.2
Min nTPM: 73.0
Sample A Female 99.2
Sample B Female 73.0
Sample C Male 88.5
Sample D Male 93.3
Superior colliculi
nTPM: 80.6
Samples: 4

Max nTPM: 90.1
Min nTPM: 60.6
Sample A Female 90.1
Sample B Female 60.6
Sample C Male 88.3
Sample D Male 83.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 30.4
Samples: 4

Max nTPM: 31.6
Min nTPM: 28.8
Sample A Male 28.8
Sample B Male 31.6
Sample C Female 29.4
Sample D Female 31.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.3
2401 Antisense, RP_Baylor_102741, Mouse strain C57BL/6J (56 days, male) 1.3
2402 Antisense, RP_Baylor_102741, Mouse strain C57BL/6J (56 days, male) 0.5

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