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TISSUE PRIMARY DATA KIDNEY Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN NASOPHARYNX ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
ANTIBODIES
AND
VALIDATION
Dictionary
Kidney
Tissue proteome
Kidney
KIDNEY - Expression summary
Protein expression
Kidneyi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
h
m
l
n
Bowman's capsule: Not detected
Cells in glomeruli: Not detected
Collecting ducts: Low
Distal tubules: Low
Proximal tubules (cell body): Not detected
Proximal tubules (microvilli): Not detected
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Cytoplasmic staining in collecting ducts. Additional microvilli staining in proximal tubules and cytoplasmic staining in distal tubules and endothelia.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:909.9 nTPM
HPA:97.9 nTPM
GTEx:909.9 nTPM
FANTOM5:2001.1 Scaled Tags Per Million

KIDNEY - Multiplex stainingi

Antibody localization in the annotated cell types/states of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state-specific markers, and subcellular location. The scores are based on multiplex immunohistochemistry profiling in selected tissues.

Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity, while additional locations are characterized by lower overlap and weaker antibody signal intensity.

The antibody of interest is reported in green, while cell types/states are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.

Read more
- Antibody HPA042302
Main location Collecting ducts
Additional location Distal tubules
Endothelia
Proximal tubules
Antibody overlap>75%
LocationCytoplasm
Antibody overlap<25%
LocationMicrovilli
Antibody overlap50%-25%
LocationCytoplasm
No antibody overlap
Antibody overlap<25%
LocationCytoplasm

KIDNEY - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Read more
Antibody HPA042302
Bowman's capsule Not detected
Cells in glomeruli Not detected
Collecting ducts Low
Distal tubules Low
Proximal tubules (cell body) Not detected
Proximal tubules (microvilli) Not detected


KIDNEY - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Read more
Average nTPM 97.9
overview
Female, age 58
Kidney sample 55
nTPM: 127.2
Cell types%
Cells in tubules:
60

Cells in glomeruli:
20

Fibroblasts:
5

Other cell types:
15

overview
Female, age 67
Kidney sample 56
nTPM: 178.8
Cell types%
Cells in tubules:
70

Cells in glomeruli:
15

Fibroblasts:
10

Other cell types:
5

overview
Female, age 55
Kidney sample 57
nTPM: 145.5
Cell types%
Cells in tubules:
80

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
5

overview
Male, age 46
Kidney sample 58
nTPM: 122
Cell types%
Cells in tubules:
60

Cells in glomeruli:
25

Fibroblasts:
5

Other cell types:
10

overview
Female, age 57
Kidney sample 358
nTPM: 39.8
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Male, age 78
Kidney sample 377
nTPM: 80.9
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
20

overview
Male, age 73
Kidney sample 380
nTPM: 97.9
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Female, age 59
Kidney sample 394
nTPM: 62.1
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
15

overview
Female, age 48
Kidney sample 414
nTPM: 26.7
Cell types%
Cells in tubules:
60

Cells in glomeruli:
5

Fibroblasts:
10

Other cell types:
25


KIDNEY - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 909.9
GTEx sample id Sample description nTPM
Kidney - Cortex
Average nTPM: 909.9
Samples: 85

Max nTPM: 3484.3
Min nTPM: 71.3
Std nTPM: 753.4
Median nTPM: 664.9
GTEX-ZE9C-1426-SM-4WKGM 60-69 years, male 3484.3
GTEX-17F97-1926-SM-7IGM4 50-59 years, male 3352.6
GTEX-11TTK-1926-SM-5PNW8 60-69 years, female 2811.6
GTEX-QDVN-1626-SM-48TZC 50-59 years, male 2771.7
GTEX-13RTJ-2226-SM-5S2Q1 60-69 years, male 2615.1
GTEX-1PWST-2226-SM-EVR3G 70-79 years, male 2275.0
GTEX-1CB4J-1926-SM-7MGX8 60-69 years, male 2070.2
GTEX-145MN-0326-SM-5QGQI 30-39 years, male 1963.7
GTEX-1N2DW-1826-SM-EAZ54 50-59 years, male 1915.8
GTEX-1A3MW-2226-SM-73KUX 60-69 years, female 1825.4
GTEX-ZLFU-0926-SM-5P9F8 40-49 years, male 1755.1
GTEX-14C39-2126-SM-664OH 40-49 years, male 1672.5
GTEX-ZVZP-0926-SM-5GIDB 50-59 years, male 1672.1
GTEX-QDT8-1726-SM-EYYV6 30-39 years, female 1574.5
GTEX-ZYFG-1626-SM-5GZYY 60-69 years, female 1549.1
GTEX-P4QS-1126-SM-3NMD5 60-69 years, male 1501.5
GTEX-1F48J-2226-SM-7MXTN 50-59 years, female 1484.8
GTEX-1R9PO-1626-SM-E6CPT 60-69 years, female 1460.8
GTEX-NPJ8-2226-SM-3TW8D 40-49 years, male 1426.6
GTEX-17F96-1926-SM-7MGWY 70-79 years, male 1402.6
GTEX-1JMQK-1926-SM-CJI3B 60-69 years, male 1286.7
GTEX-1J1OQ-1426-SM-AHZ3P 40-49 years, female 1241.2
GTEX-1GTWX-1826-SM-9QEHG 60-69 years, male 1222.5
GTEX-1HB9E-1826-SM-D4P33 50-59 years, male 1205.6
GTEX-O5YV-1226-SM-EV795 60-69 years, female 1181.0
GTEX-147F4-2626-SM-5Q5CS 50-59 years, male 1158.8
GTEX-16MT8-1926-SM-7EPGL 60-69 years, female 1111.4
GTEX-1AX8Z-2326-SM-731CR 60-69 years, male 1076.3
GTEX-1MUQO-2526-SM-E9TJN 60-69 years, male 1014.5
GTEX-1497J-0826-SM-5NQAJ 60-69 years, male 998.0
GTEX-XPVG-0526-SM-4B65N 50-59 years, male 989.1
GTEX-11GS4-2326-SM-5A5KS 60-69 years, male 936.3
GTEX-1JJ6O-2526-SM-AHZ3J 60-69 years, male 894.2
GTEX-REY6-1826-SM-EAZAT 60-69 years, male 856.5
GTEX-1E2YA-1626-SM-7MGXS 50-59 years, male 834.9
GTEX-1GF9W-1326-SM-7P8PX 60-69 years, male 831.2
GTEX-1399S-0526-SM-5IJG8 30-39 years, female 809.3
GTEX-Y5V6-2026-SM-5IFHO 60-69 years, male 781.1
GTEX-1C6VQ-2326-SM-7IGN1 50-59 years, male 780.7
GTEX-1JMPZ-1226-SM-ARU8Y 30-39 years, male 769.5
GTEX-13OVI-1126-SM-5KLZF 60-69 years, female 718.1
GTEX-1H3VY-1926-SM-9JGHJ 50-59 years, male 676.2
GTEX-1IL2V-1826-SM-ARU7R 70-79 years, male 664.9
GTEX-1K9T9-1826-SM-CXZK2 50-59 years, female 657.4
GTEX-ZC5H-1726-SM-5HL7X 40-49 years, female 653.2
GTEX-12696-0926-SM-5FQTV 60-69 years, male 639.0
GTEX-QLQW-1626-SM-CMKFE 30-39 years, male 603.6
GTEX-1LG7Y-2726-SM-D5OVW 50-59 years, male 601.0
GTEX-14C5O-2026-SM-5YYB1 60-69 years, male 580.3
GTEX-1A8FM-2026-SM-7P8RN 50-59 years, female 579.6
GTEX-1H3NZ-2126-SM-9WPQ6 60-69 years, male 573.3
GTEX-1QP6S-1526-SM-EXUSG 40-49 years, male 567.3
GTEX-ZDXO-0226-SM-4WKH7 60-69 years, male 563.7
GTEX-1JMLX-1526-SM-AHZ3N 50-59 years, male 524.2
GTEX-S33H-1426-SM-EZ6L7 30-39 years, male 513.5
GTEX-1GN1U-2126-SM-AHZ4J 50-59 years, female 449.5
GTEX-11OF3-1326-SM-5N9FJ 60-69 years, male 407.8
GTEX-1HCU7-1826-SM-A9G2A 50-59 years, male 387.0
GTEX-15CHQ-2126-SM-6871M 60-69 years, male 375.2
GTEX-1I1GP-1926-SM-CNNQU 50-59 years, male 373.6
GTEX-T5JC-1526-SM-4DM68 20-29 years, male 359.2
GTEX-1IKK5-0926-SM-A9G2U 60-69 years, male 328.7
GTEX-12WSG-0826-SM-5EQ5A 50-59 years, female 324.1
GTEX-13O1R-2526-SM-5N9FW 60-69 years, male 321.1
GTEX-Y5V5-1226-SM-EYYVP 60-69 years, female 315.0
GTEX-1GMR3-2426-SM-7MXV2 40-49 years, male 308.8
GTEX-1HBPI-2026-SM-CE6RZ 50-59 years, male 264.2
GTEX-1BAJH-1826-SM-731DA 70-79 years, male 259.5
GTEX-1NV8Z-2226-SM-EXOJ2 60-69 years, male 257.6
GTEX-1KWVE-0826-SM-CXZKO 30-39 years, male 246.1
GTEX-1N2EF-1426-SM-EXUSH 60-69 years, male 245.8
GTEX-1EKGG-2226-SM-7IGOA 60-69 years, male 236.3
GTEX-1GF9V-1926-SM-9JGHE 60-69 years, male 233.2
GTEX-13OW6-1826-SM-5N9F9 50-59 years, male 226.8
GTEX-13NYB-1726-SM-5N9G2 40-49 years, male 213.5
GTEX-1JMQJ-1726-SM-E9U4V 50-59 years, male 211.9
GTEX-15DYW-2026-SM-6AJBD 60-69 years, female 207.4
GTEX-RN64-1626-SM-48FD7 50-59 years, male 192.9
GTEX-17HHY-2326-SM-7KFSR 50-59 years, male 176.6
GTEX-14E6D-2526-SM-5YYA9 50-59 years, male 152.8
GTEX-T6MN-1826-SM-EXOHN 50-59 years, male 144.2
GTEX-ZYT6-2226-SM-5GIC9 30-39 years, male 142.5
GTEX-13OVL-1826-SM-5KLZR 50-59 years, male 129.2
GTEX-13112-2126-SM-5GCO4 50-59 years, male 103.3
GTEX-1OJC4-2326-SM-DTXA5 50-59 years, female 71.3
Show allShow less
Kidney - Medulla
Average nTPM: 699.1
Samples: 4

Max nTPM: 1491.1
Min nTPM: 103.1
Std nTPM: 529.3
Median nTPM: 601.1
GTEX-RU72-1926-SM-EAZ3F 50-59 years, female 1491.1
GTEX-TKQ2-0626-SM-EZ6LB 50-59 years, male 844.9
GTEX-T5JC-1626-SM-EZ6KW 20-29 years, male 357.3
GTEX-R55E-2026-SM-EZ6L1 20-29 years, male 103.1

KIDNEY - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 2001.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Kidney
Scaled Tags Per Million: 2001.1
FF:10017-101C8 60,62,63 years, female 2001.1

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