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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:204.8 nTPM
HPA:204.8 nTPM
GTEx:156.0 nTPM
FANTOM5:258.1 Scaled Tags Per Million
Pig:36.1 nTPM
Mouse:16.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 204.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 188.6
1870 Female, age 42, unknown 203.3
2828 Female, age 72, unknown 200.6
2411 Female, age 72, unknown 200.1
1830 Male, age 51, unknown 195.8
2019 Male, age 18, unknown 195.1
1833 Male, age 53, unknown 188.2
2219 Male, age 76, both hemispheres 179.9
2586 Male, age 75, left hemisphere 176.2
2666 Male, age 74, left hemisphere 174.7
1827 Male, age 72, unknown 171.7
Dorsal raphe nucleus
nTPM: 187.7
2750 Male, age 76, both hemispheres 222.5
2016 Female, age 72, unknown 192.0
1828 Male, age 53, unknown 179.0
2047 Male, age 72, unknown 174.3
2298 Female, age 72, unknown 170.8
Inferior colliculus
nTPM: 185.2
1890 Male, age 53, unknown 202.7
2097 Female, age 72, unknown 184.4
1848 Female, age 42, unknown 178.8
2849 Male, age 72, unknown 175.1
Median raphe nucleus
nTPM: 165.5
2220 Male, age 76, midline 165.5
Pedunculopontine tegmental nucleus
nTPM: 186.1
1921 Female, age 85, both hemispheres 197.1
2334 Male, age 80, both hemispheres 196.0
2338 Male, age 61, both hemispheres 165.0
Periaquaductal grey, anterior
nTPM: 176.3
2502 Female, age 75, unknown 182.5
1947 Male, age 18, unknown 179.7
1795 Male, age 51, unknown 166.7
Periaquaductal grey, dorsal
nTPM: 171.3
2464 Female, age 72, unknown 185.5
2850 Male, age 76, both hemispheres 170.6
1831 Male, age 72, unknown 164.9
1840 Male, age 53, unknown 164.4
Periaquaductal grey, lateral
nTPM: 177.4
2272 Male, age 74, both hemispheres 179.9
2140 Male, age 76, both hemispheres 178.8
2053 Male, age 18, unknown 173.4
Pretectal area
nTPM: 180.1
2316 Male, age 76, right hemisphere 207.4
2667 Female, age 75, unknown 196.1
1817 Female, age 42, unknown 185.7
2007 Male, age 72, unknown 182.8
1815 Male, age 53, unknown 182.4
2273 Male, age 74, both hemispheres 182.0
2224 Female, age 72, unknown 175.1
1944 Female, age 72, unknown 171.7
2825 Male, age 18, unknown 171.6
2407 Male, age 75, both hemispheres 164.0
1816 Male, age 51, unknown 162.6
Red nucleus
nTPM: 204.8
2227 Male, age 72, unknown 220.6
2769 Male, age 72, unknown 220.6
1865 Male, age 51, unknown 217.8
2785 Male, age 18, unknown 216.1
1904 Male, age 53, unknown 215.5
2503 Female, age 72, unknown 214.5
1954 Female, age 42, unknown 211.1
1821 Female, age 72, unknown 206.8
2823 Male, age 76, right hemisphere 203.3
2588 Male, age 74, left hemisphere 188.7
2725 Female, age 75, unknown 175.6
2584 Male, age 75, left hemisphere 167.6
Substantia nigra
nTPM: 177.1
1889 Female, age 72, unknown 188.1
1851 Male, age 51, unknown 185.8
2583 Male, age 75, right hemisphere 183.7
2699 Male, age 18, unknown 181.8
1941 Male, age 53, unknown 173.9
2241 Male, age 72, unknown 173.9
2665 Male, age 74, both hemispheres 172.6
1916 Female, age 42, unknown 172.4
2409 Female, age 72, unknown 172.0
2590 Female, age 75, unknown 166.4
Superior colliculus
nTPM: 187.1
1913 Female, age 42, unknown 217.6
1995 Male, age 72, unknown 210.4
1895 Male, age 76, right hemisphere 200.6
2668 Female, age 75, unknown 200.3
1839 Male, age 51, unknown 185.1
2587 Male, age 74, left hemisphere 183.5
1796 Male, age 53, unknown 174.3
2261 Male, age 18, unknown 172.1
2087 Female, age 72, unknown 168.4
2664 Male, age 75, both hemispheres 158.4
Ventral tegmental area
nTPM: 181.8
2410 Female, age 72, unknown 193.2
1942 Male, age 51, unknown 186.1
1915 Female, age 42, unknown 181.0
2021 Male, age 53, unknown 181.0
2218 Male, age 76, both hemispheres 176.7
2223 Female, age 72, unknown 173.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 156.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 156.0
Samples: 139

Max nTPM: 519.4
Min nTPM: 52.7
Std nTPM: 71.8
Median nTPM: 137.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 519.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 439.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 428.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 306.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 278.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 273.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 272.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 269.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 269.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 267.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 258.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 250.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 241.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 238.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 234.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 234.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 231.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 226.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 221.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 218.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 214.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 214.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 214.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 209.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 209.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 208.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 207.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 198.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 195.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 195.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 194.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 194.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 191.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 191.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 189.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 187.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 186.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 186.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 184.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 184.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 179.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 178.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 177.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 174.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 173.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 172.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 170.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 169.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 169.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 168.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 166.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 165.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 165.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 164.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 163.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 163.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 159.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 158.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 154.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 153.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 153.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 150.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 148.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 147.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 146.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 143.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 142.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 140.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 137.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 134.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 133.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 133.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 133.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 133.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 131.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 130.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 129.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 127.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 127.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 127.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 125.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 125.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 125.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 121.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 121.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 120.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 119.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 119.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 119.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 118.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 118.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 115.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 114.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 113.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 113.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 112.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 109.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 109.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 109.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 107.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 106.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 106.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 105.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 105.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 104.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 104.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 104.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 104.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 103.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 103.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 101.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 100.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 99.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 98.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 98.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 96.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 95.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 94.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 93.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 92.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 90.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 87.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 82.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 82.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 78.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 77.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 75.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 74.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 68.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 68.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 64.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 64.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 64.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 59.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 52.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 258.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 258.1
FF:10158-103A5 76 years, female 258.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 36.1
Pig sample Sample description nTPM
Midbrain
nTPM: 36.2
Samples: 4

Max nTPM: 67.4
Min nTPM: 21.3
Sample A Female 67.4
Sample B Female 28.9
Sample C Male 27.0
Sample D Male 21.3
Periaqueductal gray
nTPM: 28.0
Samples: 3

Max nTPM: 31.5
Min nTPM: 24.9
Sample B Female 31.5
Sample C Male 27.5
Sample D Male 24.9
Substantia nigra
nTPM: 25.8
Samples: 4

Max nTPM: 32.9
Min nTPM: 20.9
Sample A Female 32.9
Sample B Female 20.9
Sample C Male 20.9
Sample D Male 28.4
Superior colliculi
nTPM: 25.5
Samples: 4

Max nTPM: 31.8
Min nTPM: 17.7
Sample A Female 31.8
Sample B Female 17.7
Sample C Male 27.3
Sample D Male 25.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 16.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 16.0
Samples: 4

Max nTPM: 18.3
Min nTPM: 14.1
Sample A Male 14.1
Sample B Male 14.1
Sample C Female 17.5
Sample D Female 18.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
69114097 Antisense, RP_050317_01_B07, Mouse strain C57BL/6J (56 days, male) 0.1

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