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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 270.6
Min nTPM: 18.4
Std nTPM: 51.7
Median nTPM:
452_1
88 years, female
270.6
506_1
65 years, male
244.2
163_1
78 years, male
235.2
353_1
82 years, female
217.9
377_1
82 years, female
209.0
172_1
72 years, female
197.3
386_1
76 years, male
190.5
316_1
62 years, male
190.3
356_1
87 years, female
186.5
318_1
68 years, male
185.2
292_1
71 years, male
182.4
177_1
74 years, male
179.4
295_1
61 years, female
178.7
404_1
82 years, female
173.6
425_1
59 years, female
172.9
348_1
84 years, male
168.1
352_1
62 years, male
168.0
320_1
89 years, female
167.6
321_1
62 years, female
167.5
406_1
79 years, male
163.2
376_1
75 years, female
162.5
351_1
91 years, male
161.7
322_1
76 years, male
161.4
291_1
76 years, male
157.7
335_1
73 years, female
155.0
355_1
70 years, female
154.8
319_1
81 years, male
154.5
243_1
75 years, male
153.3
350_1
84 years, female
151.8
405_1
91 years, male
151.7
173_1
67 years, male
149.6
264_1
73 years, female
146.6
349_1
83 years, male
138.9
379_1
60 years, male
136.4
286_1
68 years, female
136.2
293_1
68 years, female
135.2
517_1
88 years, male
134.0
396_1
62 years, male
131.4
447_1
81 years, male
131.3
503_1
68 years, male
131.1
229_1
69 years, female
128.0
251_1
78 years, male
127.0
354_1
81 years, female
126.6
6_1
73 years, female
123.1
17_1
71 years, male
119.6
480_1
63 years, male
116.7
254_1
77 years, female
115.9
288_1
66 years, female
114.6
153_1
70 years, female
112.3
317_1
60 years, male
111.1
120_1
70 years, female
109.9
99_1
64 years, male
105.8
115_1
83 years, male
105.4
2_1
77 years, female
104.7
266_1
85 years, male
104.4
189_1
76 years, male
104.2
18_1
88 years, male
103.8
394_1
75 years, female
103.3
375_1
74 years, female
102.8
237_1
82 years, male
102.5
4_1
88 years, female
102.0
109_1
81 years, female
101.2
139_1
64 years, female
101.0
384_1
83 years, male
101.0
265_1
87 years, male
97.5
35_1
74 years, female
97.2
324_1
76 years, male
91.2
246_1
77 years, male
91.0
9_1
66 years, female
90.9
314_1
67 years, male
90.6
526_1
61 years, male
90.4
218_1
71 years, female
90.2
518_1
75 years, female
89.2
145_1
84 years, male
88.6
501_1
88 years, male
88.1
468_1
89 years, male
87.3
41_1
94 years, female
83.9
311_1
78 years, male
83.3
347_1
72 years, male
79.1
81_1
67 years, male
78.2
142_1
61 years, female
78.2
43_1
64 years, female
77.6
313_1
79 years, female
71.5
126_1
63 years, male
68.6
499_1
55 years, female
67.2
137_1
83 years, male
66.6
217_1
76 years, male
62.6
315_1
62 years, female
61.1
149_1
88 years, male
56.8
389_1
86 years, female
55.6
42_1
85 years, male
54.8
466_1
57 years, female
53.7
119_1
70 years, female
53.1
89_1
63 years, male
52.7
413_1
59 years, female
50.1
117_1
61 years, male
48.9
32_1
67 years, male
48.5
415_1
77 years, female
44.6
162_1
79 years, female
40.6
414_1
84 years, female
40.6
307_1
66 years, female
36.5
495_1
57 years, female
25.5
491_1
89 years, female
25.1
490_1
67 years, female
20.1
308_1
70 years, female
18.4
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
