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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:182.7 nTPM
HPA:182.7 nTPM
GTEx:198.6 nTPM
FANTOM5:115.0 Scaled Tags Per Million
Pig:35.2 nTPM
Mouse:181.8 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 182.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 162.2
2219 Male, age 76, both hemispheres 173.5
1827 Male, age 72, unknown 171.3
2828 Female, age 72, unknown 169.9
2666 Male, age 74, left hemisphere 166.5
2019 Male, age 18, unknown 160.9
2411 Female, age 72, unknown 159.2
1833 Male, age 53, unknown 157.2
1870 Female, age 42, unknown 156.0
2586 Male, age 75, left hemisphere 155.5
1830 Male, age 51, unknown 152.0
Dorsal raphe nucleus
nTPM: 159.6
2298 Female, age 72, unknown 169.2
2750 Male, age 76, both hemispheres 166.3
2047 Male, age 72, unknown 165.1
1828 Male, age 53, unknown 154.0
2016 Female, age 72, unknown 143.5
Inferior colliculus
nTPM: 156.4
2097 Female, age 72, unknown 160.1
2849 Male, age 72, unknown 157.3
1890 Male, age 53, unknown 155.8
1848 Female, age 42, unknown 152.4
Median raphe nucleus
nTPM: 182.7
2220 Male, age 76, midline 182.7
Pedunculopontine tegmental nucleus
nTPM: 162.9
2334 Male, age 80, both hemispheres 166.7
1921 Female, age 85, both hemispheres 164.4
2338 Male, age 61, both hemispheres 157.5
Periaquaductal grey, anterior
nTPM: 159.2
1795 Male, age 51, unknown 168.5
1947 Male, age 18, unknown 162.0
2502 Female, age 75, unknown 147.0
Periaquaductal grey, dorsal
nTPM: 152.8
1831 Male, age 72, unknown 158.8
2850 Male, age 76, both hemispheres 153.2
1840 Male, age 53, unknown 150.4
2464 Female, age 72, unknown 148.9
Periaquaductal grey, lateral
nTPM: 148.8
2272 Male, age 74, both hemispheres 155.2
2053 Male, age 18, unknown 151.0
2140 Male, age 76, both hemispheres 140.3
Pretectal area
nTPM: 167.4
1816 Male, age 51, unknown 189.7
1817 Female, age 42, unknown 185.4
2007 Male, age 72, unknown 185.4
1944 Female, age 72, unknown 183.1
1815 Male, age 53, unknown 178.1
2667 Female, age 75, unknown 167.1
2224 Female, age 72, unknown 156.6
2407 Male, age 75, both hemispheres 155.0
2825 Male, age 18, unknown 154.5
2273 Male, age 74, both hemispheres 148.8
2316 Male, age 76, right hemisphere 138.4
Red nucleus
nTPM: 153.3
2584 Male, age 75, left hemisphere 167.1
2785 Male, age 18, unknown 161.1
2725 Female, age 75, unknown 159.2
2823 Male, age 76, right hemisphere 155.9
1821 Female, age 72, unknown 154.9
2588 Male, age 74, left hemisphere 153.0
2503 Female, age 72, unknown 150.4
1954 Female, age 42, unknown 149.8
1865 Male, age 51, unknown 148.5
2769 Male, age 72, unknown 147.4
1904 Male, age 53, unknown 146.6
2227 Male, age 72, unknown 146.2
Substantia nigra
nTPM: 173.5
1916 Female, age 42, unknown 200.0
2665 Male, age 74, both hemispheres 190.2
1941 Male, age 53, unknown 186.2
1851 Male, age 51, unknown 180.1
1889 Female, age 72, unknown 176.8
2699 Male, age 18, unknown 167.7
2241 Male, age 72, unknown 163.5
2409 Female, age 72, unknown 161.0
2583 Male, age 75, right hemisphere 156.5
2590 Female, age 75, unknown 153.2
Superior colliculus
nTPM: 161.4
2668 Female, age 75, unknown 188.4
1796 Male, age 53, unknown 171.4
2087 Female, age 72, unknown 170.4
2587 Male, age 74, left hemisphere 162.9
2261 Male, age 18, unknown 159.3
1895 Male, age 76, right hemisphere 155.5
2664 Male, age 75, both hemispheres 154.8
1839 Male, age 51, unknown 153.1
1913 Female, age 42, unknown 151.9
1995 Male, age 72, unknown 146.4
Ventral tegmental area
nTPM: 166.7
2218 Male, age 76, both hemispheres 181.0
1915 Female, age 42, unknown 178.0
2410 Female, age 72, unknown 177.1
2223 Female, age 72, unknown 155.4
2021 Male, age 53, unknown 154.8
1942 Male, age 51, unknown 154.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 198.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 198.6
Samples: 139

Max nTPM: 477.6
Min nTPM: 75.4
Std nTPM: 76.5
Median nTPM: 187.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 477.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 413.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 409.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 361.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 347.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 338.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 338.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 338.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 310.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 310.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 308.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 306.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 303.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 297.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 292.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 291.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 286.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 285.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 280.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 279.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 279.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 278.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 276.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 276.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 275.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 269.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 267.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 265.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 265.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 262.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 262.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 261.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 257.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 255.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 250.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 248.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 245.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 245.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 243.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 237.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 236.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 234.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 233.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 232.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 229.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 229.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 228.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 224.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 220.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 220.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 217.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 215.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 213.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 212.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 212.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 209.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 208.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 206.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 205.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 204.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 202.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 201.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 200.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 199.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 192.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 190.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 188.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 187.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 187.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 187.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 185.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 184.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 183.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 183.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 182.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 181.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 179.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 179.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 176.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 175.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 172.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 172.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 171.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 170.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 169.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 167.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 166.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 165.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 165.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 165.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 164.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 163.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 162.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 160.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 160.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 158.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 155.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 154.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 150.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 147.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 147.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 142.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 140.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 138.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 136.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 133.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 132.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 131.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 127.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 127.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 123.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 122.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 121.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 120.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 119.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 119.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 116.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 115.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 113.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 111.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 111.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 110.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 108.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 107.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 106.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 105.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 103.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 102.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 98.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 96.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 96.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 94.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 93.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 92.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 90.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 89.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 88.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 78.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 75.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 115.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 115.0
FF:10158-103A5 76 years, female 115.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 35.2
Pig sample Sample description nTPM
Midbrain
nTPM: 35.2
Samples: 4

Max nTPM: 50.9
Min nTPM: 29.4
Sample A Female 30.0
Sample B Female 30.5
Sample C Male 50.9
Sample D Male 29.4
Periaqueductal gray
nTPM: 24.5
Samples: 3

Max nTPM: 33.7
Min nTPM: 19.4
Sample B Female 20.5
Sample C Male 33.7
Sample D Male 19.4
Substantia nigra
nTPM: 35.1
Samples: 4

Max nTPM: 50.3
Min nTPM: 17.6
Sample A Female 50.3
Sample B Female 25.1
Sample C Male 47.4
Sample D Male 17.6
Superior colliculi
nTPM: 33.5
Samples: 4

Max nTPM: 45.9
Min nTPM: 16.7
Sample A Female 41.8
Sample B Female 16.7
Sample C Male 45.9
Sample D Male 29.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 181.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 181.8
Samples: 4

Max nTPM: 203.2
Min nTPM: 172.2
Sample A Male 203.2
Sample B Male 176.6
Sample C Female 172.2
Sample D Female 175.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
71529917 Antisense, RP_050915_01_C08, Mouse strain C57BL/6J (56 days, male) 0.3

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