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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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115.361
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:62.4 nTPM
HPA:62.4 nTPM
FANTOM5:167.1 Scaled Tags Per Million
Pig:100.9 nTPM
Mouse:43.9 nTPM
Allen mouse:6.3 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA017960
Pons mean intensity 115.361
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 55.601
Parabrachial nucleus 70.011
Principle sensory trigeminal nucleus 15.604
Locus coeruleus 115.361
Pontine nucleus 17.466
Vestibular nucleus 13.986
Pontine reticular nucleus, oral 16.220
Lateral lemniscus 10.268
Superior paraolivary nucleus 8.429

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 62.4
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 58.0
2301 Female, age 85, both hemispheres 68.3
2188 Female, age 91, both hemispheres 59.0
2090 Male, age 80, both hemispheres 54.7
1984 Male, age 76, both hemispheres 49.9
Area postrema
nTPM: 51.7
2306 Male, age 80, both hemispheres 53.8
2054 Male, age 76, both hemispheres 52.8
2799 Male, age 61, both hemispheres 48.4
Cuneate nuclei
nTPM: 54.9
2131 Male, age 76, both hemispheres 56.7
2381 Male, age 80, both hemispheres 55.3
2376 Male, age 61, both hemispheres 52.9
Dorsal cochlear nucleus
nTPM: 50.8
2187 Female, age 91, both hemispheres 58.4
2802 Male, age 74, right hemisphere 55.7
2058 Male, age 76, both hemispheres 49.4
2378 Male, age 80, both hemispheres 46.2
2370 Male, age 61, both hemispheres 44.1
Dorsal medullary reticular nucleus
nTPM: 50.0
2088 Male, age 76, both hemispheres 53.6
2040 Female, age 85, both hemispheres 49.1
2373 Male, age 61, both hemispheres 47.2
Dorsal motor vagal complex
nTPM: 47.5
2185 Male, age 76, both hemispheres 64.7
2643 Male, age 74, both hemispheres 50.9
2844 Male, age 55, unknown 48.2
2000 Male, age 74, unknown 46.1
2133 Female, age 91, both hemispheres 44.6
2797 Male, age 61, both hemispheres 44.2
2813 Female, age 72, unknown 41.8
2807 Female, age 85, both hemispheres 39.8
Dorsal tegmental nucleus
nTPM: 47.0
2326 Male, age 74, both hemispheres 51.8
2083 Male, age 80, both hemispheres 50.1
1936 Male, age 76, left hemisphere 45.1
2358 Male, age 61, both hemispheres 41.1
Dorsolateral tegmental area
nTPM: 48.0
2751 Female, age 85, both hemispheres 56.3
2360 Male, age 74, both hemispheres 50.7
2654 Male, age 80, both hemispheres 48.6
2337 Male, age 61, both hemispheres 42.8
2141 Male, age 76, both hemispheres 41.7
Gigantocellular reticular nuclei, medullary
nTPM: 50.4
2314 Male, age 61, both hemispheres 63.3
2387 Female, age 91, both hemispheres 54.7
1876 Female, age 85, both hemispheres 50.0
2310 Male, age 80, both hemispheres 47.1
2022 Male, age 76, right hemisphere 46.9
2462 Male, age 74, both hemispheres 40.7
Gigantocellular reticular nuclei, pars
nTPM: 47.7
2336 Male, age 61, both hemispheres 52.4
2330 Male, age 80, both hemispheres 49.4
2706 Male, age 80, both hemispheres 49.2
2084 Female, age 85, both hemispheres 44.2
2168 Male, age 76, both hemispheres 43.3
Inferior olive
nTPM: 56.6
2085 Female, age 85, both hemispheres 60.9
2563 Male, age 74, both hemispheres 58.3
2178 Male, age 61, both hemispheres 57.0
2628 Female, age 91, both hemispheres 56.9
2379 Male, age 80, both hemispheres 50.0
Kolliker-Fuse nucleus
nTPM: 49.9
2793 Female, age 91, left hemisphere 64.3
2163 Male, age 80, both hemispheres 47.7
2315 Male, age 76, right hemisphere 37.7
Lateral lemniscal nuclei
nTPM: 50.9
2320 Female, age 91, left hemisphere 57.0
2453 Male, age 74, right hemisphere 50.6
2036 Male, age 80, both hemispheres 50.5
2746 Female, age 85, left hemisphere 50.1
2169 Male, age 76, both hemispheres 46.4
Lateral medullary reticular nucleus
nTPM: 55.2
2305 Male, age 74, both hemispheres 60.6
2374 Male, age 61, both hemispheres 59.7
2852 Male, age 80, both hemispheres 58.1
2190 Female, age 85, both hemispheres 54.6
2804 Female, age 91, both hemispheres 50.2
2044 Male, age 76, both hemispheres 47.8
Lateral parabrachial nucleus
nTPM: 47.4
2792 Male, age 76, both hemispheres 52.6
2013 Male, age 80, both hemispheres 48.7
2790 Male, age 61, both hemispheres 45.7
2139 Female, age 85, right hemisphere 42.5
Lateral vestibular nucleus
nTPM: 52.5
2184 Male, age 76, both hemispheres 53.2
2311 Male, age 80, both hemispheres 51.9
Locus coeruleus
nTPM: 39.3
2720 Male, age 74, both hemispheres 46.0
1980 Male, age 76, both hemispheres 40.7
2123 Female, age 91, both hemispheres 39.4
2162 Male, age 80, both hemispheres 37.7
2317 Female, age 72, unknown 37.7
2014 Male, age 55, unknown 37.1
2788 Male, age 74, unknown 36.8
Medial olivary nucleus
nTPM: 54.8
1943 Male, age 61, both hemispheres 58.0
1962 Male, age 76, both hemispheres 55.3
2138 Female, age 91, both hemispheres 53.5
2851 Male, age 80, both hemispheres 52.4
Medial parabrachial nucleus
nTPM: 53.0
2170 Female, age 91, both hemispheres 62.9
2463 Female, age 85, right hemisphere 55.9
2854 Male, age 80, both hemispheres 52.1
2786 Male, age 76, both hemispheres 49.5
2156 Male, age 61, both hemispheres 44.5
Medial periolivary nuclei
nTPM: 48.4
2458 Female, age 91, both hemispheres 55.4
2081 Male, age 80, both hemispheres 52.5
2791 Male, age 74, right hemisphere 48.8
2171 Female, age 85, both hemispheres 44.1
2063 Male, age 76, both hemispheres 40.9
Medial vestibular nucleus
nTPM: 50.5
2801 Male, age 74, both hemispheres 61.3
2803 Female, age 91, both hemispheres 52.5
2624 Male, age 61, both hemispheres 49.9
2093 Male, age 80, both hemispheres 47.9
2743 Female, age 85, both hemispheres 46.3
2134 Male, age 76, both hemispheres 45.4
Motor facial nucleus
nTPM: 48.5
2365 Male, age 74, right hemisphere 52.2
2126 Male, age 61, both hemispheres 51.8
2697 Female, age 85, both hemispheres 51.8
2795 Female, age 91, both hemispheres 48.0
2327 Male, age 80, both hemispheres 46.1
2062 Male, age 76, both hemispheres 41.2
Motor hypoglossal nucleus
nTPM: 48.8
2125 Female, age 91, both hemispheres 54.5
2182 Male, age 80, both hemispheres 54.0
2132 Female, age 85, both hemispheres 47.6
2277 Male, age 76, both hemispheres 44.4
2461 Male, age 61, both hemispheres 43.5
Motor trigeminal nucleus
nTPM: 49.6
2321 Female, age 91, both hemispheres 59.0
2560 Male, age 74, both hemispheres 56.2
2309 Male, age 76, both hemispheres 47.8
2079 Male, age 80, both hemispheres 45.0
2335 Male, age 61, both hemispheres 40.3
Nuclei of the trapezoid body
nTPM: 45.3
2368 Female, age 91, both hemispheres 51.4
2166 Male, age 80, both hemispheres 50.7
2159 Male, age 61, both hemispheres 42.3
2735 Female, age 85, both hemispheres 41.0
1983 Male, age 76, both hemispheres 40.9
Nucleus ambiguus
nTPM: 49.5
2071 Male, age 76, both hemispheres 53.9
2096 Female, age 85, both hemispheres 45.1
Nucleus cuneatus
nTPM: 57.6
2100 Male, age 76, both hemispheres 67.3
2380 Male, age 80, both hemispheres 61.0
2808 Female, age 85, both hemispheres 58.9
2564 Male, age 74, both hemispheres 58.4
2805 Female, age 91, both hemispheres 56.2
2562 Male, age 61, both hemispheres 43.8
Nucleus gracilis
nTPM: 61.9
2627 Male, age 74, both hemispheres 63.9
2382 Male, age 80, both hemispheres 61.4
2299 Female, age 85, both hemispheres 60.4
Nucleus raphe magnus
nTPM: 45.4
2459 Female, age 91, both hemispheres 54.6
2328 Male, age 80, both hemispheres 48.8
2051 Male, age 76, both hemispheres 48.1
2455 Male, age 74, both hemispheres 46.4
2172 Female, age 85, both hemispheres 40.9
2160 Male, age 61, both hemispheres 33.7
Nucleus raphe obscurus
nTPM: 62.4
2845 Female, age 85, midline 71.4
2800 Male, age 61, midline 59.8
2142 Male, age 76, midline 55.9
Nucleus raphe pallidus
nTPM: 51.8
2145 Male, age 76, midline 62.6
2183 Male, age 80, midline 49.5
1924 Male, age 61, midline 43.2
Nucleus tractus solitarii
nTPM: 39.7
2191 Female, age 85, both hemispheres 46.0
2656 Male, age 76, both hemispheres 45.0
2307 Male, age 80, both hemispheres 36.1
2144 Female, age 91, right hemisphere 31.5
Paramedian reticular nucleus
nTPM: 44.8
2057 Male, age 80, both hemispheres 47.6
2050 Female, age 85, both hemispheres 47.3
2052 Male, age 76, both hemispheres 44.1
2313 Male, age 61, both hemispheres 40.2
Parvicellular reticular nuclei
nTPM: 50.5
2119 Male, age 80, both hemispheres 51.7
2095 Male, age 76, both hemispheres 50.4
2558 Male, age 74, both hemispheres 49.3
Parvicellular reticular nuclei, medullary
nTPM: 46.3
2189 Female, age 91, both hemispheres 50.5
2091 Female, age 85, both hemispheres 46.9
2181 Male, age 80, left hemisphere 41.4
Peritrigeminal nucleus
nTPM: 47.1
2067 Female, age 85, both hemispheres 48.4
2136 Male, age 76, both hemispheres 48.2
2179 Male, age 61, both hemispheres 44.7
Pontine nuclei
nTPM: 50.4
2454 Male, age 74, left hemisphere 60.6
2319 Female, age 91, both hemispheres 58.1
2109 Female, age 72, unknown 53.8
1863 Male, age 55, unknown 52.4
2115 Male, age 80, left hemisphere 51.6
1968 Male, age 76, left hemisphere 45.2
2787 Female, age 85, both hemispheres 45.0
2727 Male, age 61, right hemisphere 36.9
Pontine raphe nucleus
nTPM: 42.0
2853 Male, age 76, midline 42.2
2122 Female, age 85, midline 41.8
Posteroventral cochlear nucleus
nTPM: 51.0
2135 Female, age 91, both hemispheres 65.4
2341 Male, age 80, both hemispheres 58.0
2070 Male, age 76, both hemispheres 47.0
2371 Male, age 61, both hemispheres 45.0
2752 Female, age 85, both hemispheres 39.5
Prepositus hypoglossal nucleus
nTPM: 46.0
2855 Female, age 85, right hemisphere 54.8
2086 Male, age 80, both hemispheres 37.2
Principal sensory trigeminal nucleus
nTPM: 48.7
2367 Female, age 91, left hemisphere 62.0
2324 Male, age 76, both hemispheres 52.9
2008 Male, age 80, left hemisphere 44.0
2158 Male, age 61, both hemispheres 36.0
Reticular pontine nucleus, caudal
nTPM: 52.1
2559 Male, age 74, both hemispheres 61.6
2457 Female, age 91, both hemispheres 54.4
2332 Male, age 80, right hemisphere 46.8
2092 Male, age 76, both hemispheres 45.8
Reticular pontine nucleus, oral
nTPM: 52.4
2361 Male, age 74, both hemispheres 57.2
2366 Female, age 91, both hemispheres 56.6
2167 Male, age 76, both hemispheres 49.7
1939 Male, age 80, both hemispheres 49.2
2012 Female, age 85, both hemispheres 49.1
Reticulotegmental nucleus
nTPM: 48.2
2322 Female, age 91, both hemispheres 55.7
2452 Male, age 74, both hemispheres 49.9
2333 Male, age 80, both hemispheres 46.1
2325 Male, age 76, both hemispheres 41.1
Spinal trigeminal nucleus, caudal
nTPM: 51.6
2447 Male, age 76, both hemispheres 56.5
2312 Male, age 61, both hemispheres 53.4
2390 Female, age 91, both hemispheres 53.1
2308 Male, age 80, both hemispheres 48.3
2642 Male, age 74, both hemispheres 46.9
Spinal trigeminal nucleus, interpolar
nTPM: 45.5
2625 Male, age 61, both hemispheres 48.8
2389 Female, age 91, both hemispheres 47.8
2386 Female, age 85, both hemispheres 45.7
2033 Male, age 80, both hemispheres 44.0
2066 Male, age 76, right hemisphere 41.2
Spinal trigeminal nucleus, oral
nTPM: 47.5
2164 Male, age 80, both hemispheres 51.5
1978 Male, age 76, both hemispheres 47.6
2737 Female, age 85, both hemispheres 43.5
Spinal vestibular nucleus
nTPM: 48.5
2384 Male, age 74, both hemispheres 55.1
2748 Male, age 76, both hemispheres 51.8
2806 Female, age 85, both hemispheres 51.4
2186 Female, age 91, both hemispheres 50.1
2780 Male, age 80, both hemispheres 43.1
2796 Male, age 61, both hemispheres 39.2
Subcoeruleus area
nTPM: 46.6
2369 Female, age 85, left hemisphere 60.1
2089 Male, age 76, left hemisphere 45.7
1958 Male, age 80, both hemispheres 43.6
2451 Male, age 74, both hemispheres 43.0
2323 Female, age 91, left hemisphere 40.5
Superior olive
nTPM: 50.2
2561 Female, age 91, both hemispheres 54.7
2329 Male, age 80, right hemisphere 54.2
2364 Male, age 74, right hemisphere 50.5
2020 Male, age 76, both hemispheres 47.6
1875 Female, age 85, both hemispheres 44.1
Superior vestibular nucleus
nTPM: 50.2
2383 Male, age 74, both hemispheres 55.2
2061 Male, age 76, both hemispheres 49.7
2015 Male, age 80, both hemispheres 45.5
Ventral medullary reticular nucleus
nTPM: 52.7
2372 Male, age 61, both hemispheres 55.9
2060 Male, age 76, both hemispheres 49.5
Ventral periolivary nuclei
nTPM: 45.8
2794 Female, age 91, left hemisphere 46.8
2023 Male, age 76, both hemispheres 46.4
2165 Male, age 80, both hemispheres 45.3
2130 Female, age 85, both hemispheres 44.8
Ventrolateral medulla, A1-C1 cell groups
nTPM: 47.7
2118 Male, age 80, both hemispheres 50.3
2180 Male, age 61, both hemispheres 50.1
2302 Female, age 91, both hemispheres 48.0
1986 Male, age 76, both hemispheres 45.5
2741 Female, age 85, both hemispheres 44.4
Ventrolateral tegmental area, A5 NE cell group
nTPM: 48.5
2456 Female, age 91, both hemispheres 56.9
2840 Female, age 85, both hemispheres 53.8
2449 Male, age 74, both hemispheres 49.5
2161 Male, age 80, both hemispheres 46.5
1959 Male, age 76, both hemispheres 43.4
2359 Male, age 61, both hemispheres 40.9

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 167.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 167.1
FF:10182-103D2 60 years, female 226.6
FF:10165-103B3 76 years, female 107.5
Medulla oblongata
Scaled Tags Per Million: 131.6
FF:10174-103C3 60 years, female 154.8
FF:10038-101F2 18-64 years, mixed 137.4
FF:10155-103A2 76 years, female 102.6
Pons
Scaled Tags Per Million: 107.1
FF:10033-101E6 18-54 years, mixed 107.1

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 100.9
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 100.9
Samples: 4

Max nTPM: 108.6
Min nTPM: 88.4
Sample A Female 108.6
Sample B Female 88.4
Sample C Male 98.7
Sample D Male 108.0
Pons
nTPM: 76.8
Samples: 4

Max nTPM: 104.5
Min nTPM: 57.0
Sample A Female 104.5
Sample B Female 57.9
Sample C Male 57.0
Sample D Male 87.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.9
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 43.8
Samples: 4

Max nTPM: 47.1
Min nTPM: 40.4
Sample A Male 47.1
Sample B Male 40.4
Sample C Female 44.1
Sample D Female 43.7

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 6.3
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 6.3
72077454 Antisense, RP_051017_03_A08, Mouse strain C57BL/6J (56 days, male) 6.7
68845275 Antisense, RP_050224_01_E01, Mouse strain C57BL/6J (56 days, male) 5.9
Pons
Expression energy: 4.4
68845275 Antisense, RP_050224_01_E01, Mouse strain C57BL/6J (56 days, male) 4.6
72077454 Antisense, RP_051017_03_A08, Mouse strain C57BL/6J (56 days, male) 4.1

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