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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:122.1 nTPM
HPA:122.1 nTPM
GTEx:260.2 nTPM
FANTOM5:312.2 Scaled Tags Per Million
Pig:264.9 nTPM
Mouse:393.0 nTPM
Allen mouse:15.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 122.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 107.8
2586 Male, age 75, left hemisphere 113.2
2019 Male, age 18, unknown 112.3
2219 Male, age 76, both hemispheres 111.9
2666 Male, age 74, left hemisphere 111.9
1870 Female, age 42, unknown 110.4
1827 Male, age 72, unknown 109.8
2411 Female, age 72, unknown 109.5
1833 Male, age 53, unknown 100.6
1830 Male, age 51, unknown 99.5
2828 Female, age 72, unknown 99.3
Dorsal raphe nucleus
nTPM: 109.0
2298 Female, age 72, unknown 116.7
2047 Male, age 72, unknown 111.0
1828 Male, age 53, unknown 109.0
2750 Male, age 76, both hemispheres 107.6
2016 Female, age 72, unknown 100.9
Inferior colliculus
nTPM: 107.2
2097 Female, age 72, unknown 116.4
1890 Male, age 53, unknown 105.6
1848 Female, age 42, unknown 105.1
2849 Male, age 72, unknown 101.6
Median raphe nucleus
nTPM: 112.1
2220 Male, age 76, midline 112.1
Pedunculopontine tegmental nucleus
nTPM: 108.5
1921 Female, age 85, both hemispheres 110.2
2334 Male, age 80, both hemispheres 109.8
2338 Male, age 61, both hemispheres 105.3
Periaquaductal grey, anterior
nTPM: 112.3
2502 Female, age 75, unknown 112.7
1947 Male, age 18, unknown 112.4
1795 Male, age 51, unknown 111.7
Periaquaductal grey, dorsal
nTPM: 107.3
1840 Male, age 53, unknown 114.3
1831 Male, age 72, unknown 106.7
2464 Female, age 72, unknown 104.6
2850 Male, age 76, both hemispheres 103.6
Periaquaductal grey, lateral
nTPM: 98.8
2272 Male, age 74, both hemispheres 102.7
2053 Male, age 18, unknown 102.3
2140 Male, age 76, both hemispheres 91.2
Pretectal area
nTPM: 111.1
1816 Male, age 51, unknown 125.5
1944 Female, age 72, unknown 124.4
2007 Male, age 72, unknown 122.2
1817 Female, age 42, unknown 116.4
2667 Female, age 75, unknown 113.1
1815 Male, age 53, unknown 110.6
2224 Female, age 72, unknown 109.7
2407 Male, age 75, both hemispheres 101.9
2273 Male, age 74, both hemispheres 99.9
2825 Male, age 18, unknown 99.2
2316 Male, age 76, right hemisphere 99.0
Red nucleus
nTPM: 103.5
1821 Female, age 72, unknown 115.1
2785 Male, age 18, unknown 108.4
1954 Female, age 42, unknown 107.5
2725 Female, age 75, unknown 106.5
1904 Male, age 53, unknown 105.6
2584 Male, age 75, left hemisphere 101.9
2769 Male, age 72, unknown 101.1
2227 Male, age 72, unknown 100.8
2503 Female, age 72, unknown 100.4
2588 Male, age 74, left hemisphere 99.5
2823 Male, age 76, right hemisphere 98.2
1865 Male, age 51, unknown 97.5
Substantia nigra
nTPM: 122.1
1916 Female, age 42, unknown 135.6
1851 Male, age 51, unknown 130.8
1889 Female, age 72, unknown 126.8
1941 Male, age 53, unknown 126.8
2665 Male, age 74, both hemispheres 123.1
2241 Male, age 72, unknown 123.0
2699 Male, age 18, unknown 118.9
2409 Female, age 72, unknown 117.3
2583 Male, age 75, right hemisphere 112.6
2590 Female, age 75, unknown 106.0
Superior colliculus
nTPM: 108.1
2668 Female, age 75, unknown 115.4
2087 Female, age 72, unknown 114.1
2664 Male, age 75, both hemispheres 112.7
1895 Male, age 76, right hemisphere 110.2
1796 Male, age 53, unknown 107.4
2261 Male, age 18, unknown 106.5
2587 Male, age 74, left hemisphere 104.7
1839 Male, age 51, unknown 103.9
1995 Male, age 72, unknown 103.6
1913 Female, age 42, unknown 102.8
Ventral tegmental area
nTPM: 113.6
1915 Female, age 42, unknown 119.1
2410 Female, age 72, unknown 118.9
1942 Male, age 51, unknown 115.4
2218 Male, age 76, both hemispheres 113.1
2021 Male, age 53, unknown 108.4
2223 Female, age 72, unknown 107.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 260.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 260.2
Samples: 139

Max nTPM: 469.6
Min nTPM: 109.3
Std nTPM: 73.6
Median nTPM: 249.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 469.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 453.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 450.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 448.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 443.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 423.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 419.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 398.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 397.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 394.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 394.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 393.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 355.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 349.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 347.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 337.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 337.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 337.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 336.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 328.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 326.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 325.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 325.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 325.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 325.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 322.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 320.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 318.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 315.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 315.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 314.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 312.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 308.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 306.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 303.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 301.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 301.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 297.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 295.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 294.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 293.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 292.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 292.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 287.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 283.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 283.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 282.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 282.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 281.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 280.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 278.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 277.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 272.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 271.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 271.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 267.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 266.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 264.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 263.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 263.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 260.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 259.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 256.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 252.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 251.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 250.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 249.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 249.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 249.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 249.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 248.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 248.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 248.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 247.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 245.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 244.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 242.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 241.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 241.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 240.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 239.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 236.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 235.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 235.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 230.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 230.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 228.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 228.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 226.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 226.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 224.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 224.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 220.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 219.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 218.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 217.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 216.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 216.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 216.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 215.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 215.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 213.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 212.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 211.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 210.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 210.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 210.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 208.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 206.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 205.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 205.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 204.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 199.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 198.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 196.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 195.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 194.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 191.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 189.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 187.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 186.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 185.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 181.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 178.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 176.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 166.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 165.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 164.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 161.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 161.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 160.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 155.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 150.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 149.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 147.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 130.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 127.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 125.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 109.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 312.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 312.2
FF:10158-103A5 76 years, female 312.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 264.9
Pig sample Sample description nTPM
Midbrain
nTPM: 256.3
Samples: 4

Max nTPM: 319.5
Min nTPM: 229.8
Sample A Female 319.5
Sample B Female 232.7
Sample C Male 243.0
Sample D Male 229.8
Periaqueductal gray
nTPM: 192.2
Samples: 3

Max nTPM: 220.0
Min nTPM: 166.6
Sample B Female 190.0
Sample C Male 220.0
Sample D Male 166.6
Substantia nigra
nTPM: 260.0
Samples: 4

Max nTPM: 367.8
Min nTPM: 167.7
Sample A Female 367.8
Sample B Female 237.8
Sample C Male 266.6
Sample D Male 167.7
Superior colliculi
nTPM: 264.9
Samples: 4

Max nTPM: 327.7
Min nTPM: 217.7
Sample A Female 327.7
Sample B Female 265.2
Sample C Male 248.9
Sample D Male 217.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 393.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 393.0
Samples: 4

Max nTPM: 468.3
Min nTPM: 330.6
Sample A Male 468.3
Sample B Male 364.1
Sample C Female 330.6
Sample D Female 409.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.1
69782533 Antisense, RP_050505_03_B12, Mouse strain C57BL/6J (56 days, male) 15.1

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