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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA041130
Normal tissues showed moderate cytoplasmic positivity with additional nuclear staining in several tissues as well. Hematopoietic cells and squamous epithelium of esophagus, exocrine pancreas, respiratory epithelia, hepatocytes, Leydig cells and the adrenal gland displayed strong cytoplasmic immunoreactivity. Bile duct cells and cells in glomeruli were weakly stained or negative.
HPA041380
Most of the normal tissues showed weak to moderate cytoplasmic staining with occasional membranous immunoreactivity. Megakaryocytes, small intestine, renal tubules and neuronal cells were strongly stained. Lymphoid tissues, heart and smooth muscle cells were negative.
The Human Protein Atlas project is funded
