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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:301.7 nTPM
HPA:301.7 nTPM
GTEx:350.8 nTPM
FANTOM5:175.2 Scaled Tags Per Million
Pig:303.4 nTPM
Mouse:295.5 nTPM
Allen mouse:16.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 301.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 286.0
2019 Male, age 18, unknown 335.9
2586 Male, age 75, left hemisphere 335.1
2828 Female, age 72, unknown 306.9
2666 Male, age 74, left hemisphere 299.6
1827 Male, age 72, unknown 285.6
2219 Male, age 76, both hemispheres 282.5
1870 Female, age 42, unknown 267.1
2411 Female, age 72, unknown 250.6
1830 Male, age 51, unknown 250.5
1833 Male, age 53, unknown 246.6
Dorsal raphe nucleus
nTPM: 269.3
1828 Male, age 53, unknown 276.7
2750 Male, age 76, both hemispheres 275.1
2047 Male, age 72, unknown 274.4
2298 Female, age 72, unknown 262.9
2016 Female, age 72, unknown 257.5
Inferior colliculus
nTPM: 282.7
2097 Female, age 72, unknown 314.7
1890 Male, age 53, unknown 298.7
1848 Female, age 42, unknown 259.8
2849 Male, age 72, unknown 257.7
Median raphe nucleus
nTPM: 276.6
2220 Male, age 76, midline 276.6
Pedunculopontine tegmental nucleus
nTPM: 270.0
1921 Female, age 85, both hemispheres 298.9
2334 Male, age 80, both hemispheres 263.6
2338 Male, age 61, both hemispheres 247.6
Periaquaductal grey, anterior
nTPM: 274.2
1795 Male, age 51, unknown 283.3
2502 Female, age 75, unknown 279.1
1947 Male, age 18, unknown 260.1
Periaquaductal grey, dorsal
nTPM: 247.4
2850 Male, age 76, both hemispheres 256.5
1831 Male, age 72, unknown 249.7
1840 Male, age 53, unknown 243.2
2464 Female, age 72, unknown 240.5
Periaquaductal grey, lateral
nTPM: 245.2
2053 Male, age 18, unknown 250.2
2140 Male, age 76, both hemispheres 247.3
2272 Male, age 74, both hemispheres 238.1
Pretectal area
nTPM: 301.7
2007 Male, age 72, unknown 383.4
1817 Female, age 42, unknown 363.4
1816 Male, age 51, unknown 359.5
1944 Female, age 72, unknown 354.5
1815 Male, age 53, unknown 328.0
2667 Female, age 75, unknown 283.4
2316 Male, age 76, right hemisphere 261.0
2224 Female, age 72, unknown 254.1
2407 Male, age 75, both hemispheres 249.9
2825 Male, age 18, unknown 245.1
2273 Male, age 74, both hemispheres 236.4
Red nucleus
nTPM: 277.4
2785 Male, age 18, unknown 333.3
2588 Male, age 74, left hemisphere 298.6
2584 Male, age 75, left hemisphere 288.6
1821 Female, age 72, unknown 280.8
2503 Female, age 72, unknown 278.6
2725 Female, age 75, unknown 274.4
2769 Male, age 72, unknown 271.0
2227 Male, age 72, unknown 266.9
1954 Female, age 42, unknown 265.4
1904 Male, age 53, unknown 259.7
1865 Male, age 51, unknown 256.2
2823 Male, age 76, right hemisphere 255.5
Substantia nigra
nTPM: 298.6
1889 Female, age 72, unknown 345.2
2665 Male, age 74, both hemispheres 336.0
1941 Male, age 53, unknown 327.7
1916 Female, age 42, unknown 327.1
1851 Male, age 51, unknown 297.0
2241 Male, age 72, unknown 278.5
2583 Male, age 75, right hemisphere 278.5
2590 Female, age 75, unknown 269.7
2409 Female, age 72, unknown 266.9
2699 Male, age 18, unknown 259.1
Superior colliculus
nTPM: 278.5
2668 Female, age 75, unknown 308.9
2087 Female, age 72, unknown 291.4
2664 Male, age 75, both hemispheres 287.3
1895 Male, age 76, right hemisphere 286.4
2261 Male, age 18, unknown 283.2
1796 Male, age 53, unknown 276.8
1913 Female, age 42, unknown 270.5
2587 Male, age 74, left hemisphere 261.5
1839 Male, age 51, unknown 260.4
1995 Male, age 72, unknown 259.0
Ventral tegmental area
nTPM: 276.4
1915 Female, age 42, unknown 296.3
1942 Male, age 51, unknown 291.8
2218 Male, age 76, both hemispheres 278.7
2410 Female, age 72, unknown 273.0
2021 Male, age 53, unknown 262.2
2223 Female, age 72, unknown 256.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 350.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 350.8
Samples: 139

Max nTPM: 942.9
Min nTPM: 156.2
Std nTPM: 110.6
Median nTPM: 333.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 942.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 645.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 623.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 579.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 574.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 548.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 545.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 520.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 516.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 510.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 508.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 504.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 498.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 490.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 482.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 480.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 474.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 472.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 460.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 455.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 454.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 451.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 451.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 450.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 449.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 448.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 434.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 434.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 431.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 426.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 424.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 418.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 415.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 414.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 412.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 412.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 409.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 404.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 399.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 397.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 394.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 391.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 389.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 389.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 387.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 384.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 384.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 378.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 377.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 376.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 376.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 375.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 374.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 373.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 372.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 370.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 365.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 365.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 363.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 363.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 361.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 358.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 357.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 346.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 346.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 344.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 343.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 341.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 334.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 333.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 331.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 328.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 328.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 326.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 323.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 320.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 314.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 310.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 308.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 307.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 305.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 304.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 304.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 303.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 301.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 299.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 296.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 295.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 294.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 291.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 289.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 287.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 287.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 286.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 284.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 284.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 284.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 281.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 281.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 279.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 279.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 278.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 278.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 272.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 272.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 272.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 271.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 271.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 270.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 266.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 266.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 259.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 258.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 258.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 257.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 253.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 252.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 249.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 248.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 248.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 245.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 242.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 240.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 239.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 239.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 238.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 227.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 225.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 222.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 215.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 215.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 210.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 193.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 190.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 190.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 189.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 185.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 162.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 156.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 175.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 175.2
FF:10158-103A5 76 years, female 175.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 303.4
Pig sample Sample description nTPM
Midbrain
nTPM: 259.2
Samples: 4

Max nTPM: 389.1
Min nTPM: 155.0
Sample A Female 155.0
Sample B Female 190.0
Sample C Male 389.1
Sample D Male 302.7
Periaqueductal gray
nTPM: 158.5
Samples: 3

Max nTPM: 179.8
Min nTPM: 140.6
Sample B Female 155.2
Sample C Male 179.8
Sample D Male 140.6
Substantia nigra
nTPM: 196.6
Samples: 4

Max nTPM: 265.7
Min nTPM: 131.5
Sample A Female 265.7
Sample B Female 163.8
Sample C Male 225.2
Sample D Male 131.5
Superior colliculi
nTPM: 303.4
Samples: 4

Max nTPM: 356.1
Min nTPM: 219.2
Sample A Female 356.1
Sample B Female 219.2
Sample C Male 346.6
Sample D Male 291.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 295.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 295.5
Samples: 4

Max nTPM: 345.5
Min nTPM: 260.0
Sample A Male 345.5
Sample B Male 285.3
Sample C Female 260.0
Sample D Female 291.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 16.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.0
69524404 Antisense, RP_050419_04_C07, Mouse strain C57BL/6J (56 days, male) 16.0

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