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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:132.0 nTPM
HPA:132.0 nTPM
GTEx:180.9 nTPM
FANTOM5:133.7 Scaled Tags Per Million
Pig:105.9 nTPM
Mouse:88.1 nTPM
Allen mouse:6.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 132.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 124.9
2411 Female, age 72, unknown 132.0
2586 Male, age 75, left hemisphere 131.4
2828 Female, age 72, unknown 131.2
1827 Male, age 72, unknown 125.8
2019 Male, age 18, unknown 124.7
1870 Female, age 42, unknown 124.5
2219 Male, age 76, both hemispheres 122.1
1833 Male, age 53, unknown 120.0
2666 Male, age 74, left hemisphere 119.2
1830 Male, age 51, unknown 118.1
Dorsal raphe nucleus
nTPM: 130.6
2298 Female, age 72, unknown 143.3
2750 Male, age 76, both hemispheres 132.3
2047 Male, age 72, unknown 128.0
1828 Male, age 53, unknown 126.5
2016 Female, age 72, unknown 122.7
Inferior colliculus
nTPM: 121.5
2097 Female, age 72, unknown 127.7
1848 Female, age 42, unknown 121.5
1890 Male, age 53, unknown 121.4
2849 Male, age 72, unknown 115.5
Median raphe nucleus
nTPM: 129.9
2220 Male, age 76, midline 129.9
Pedunculopontine tegmental nucleus
nTPM: 124.0
2334 Male, age 80, both hemispheres 126.9
2338 Male, age 61, both hemispheres 122.8
1921 Female, age 85, both hemispheres 122.3
Periaquaductal grey, anterior
nTPM: 128.3
1795 Male, age 51, unknown 131.4
2502 Female, age 75, unknown 127.0
1947 Male, age 18, unknown 126.6
Periaquaductal grey, dorsal
nTPM: 120.4
1840 Male, age 53, unknown 122.7
2464 Female, age 72, unknown 122.1
2850 Male, age 76, both hemispheres 120.7
1831 Male, age 72, unknown 116.1
Periaquaductal grey, lateral
nTPM: 123.1
2272 Male, age 74, both hemispheres 130.6
2140 Male, age 76, both hemispheres 121.3
2053 Male, age 18, unknown 117.5
Pretectal area
nTPM: 126.8
2273 Male, age 74, both hemispheres 135.2
2007 Male, age 72, unknown 133.0
1817 Female, age 42, unknown 130.7
1816 Male, age 51, unknown 130.6
1944 Female, age 72, unknown 127.8
1815 Male, age 53, unknown 127.6
2667 Female, age 75, unknown 127.2
2224 Female, age 72, unknown 126.1
2316 Male, age 76, right hemisphere 123.6
2825 Male, age 18, unknown 121.2
2407 Male, age 75, both hemispheres 112.3
Red nucleus
nTPM: 126.5
2503 Female, age 72, unknown 135.7
2227 Male, age 72, unknown 132.3
2769 Male, age 72, unknown 130.1
2785 Male, age 18, unknown 129.5
1904 Male, age 53, unknown 128.6
2725 Female, age 75, unknown 127.8
1821 Female, age 72, unknown 127.2
1954 Female, age 42, unknown 126.1
1865 Male, age 51, unknown 124.9
2823 Male, age 76, right hemisphere 122.6
2588 Male, age 74, left hemisphere 117.8
2584 Male, age 75, left hemisphere 115.2
Substantia nigra
nTPM: 127.3
1916 Female, age 42, unknown 143.6
1851 Male, age 51, unknown 138.3
2699 Male, age 18, unknown 129.1
1889 Female, age 72, unknown 126.7
2590 Female, age 75, unknown 125.9
1941 Male, age 53, unknown 125.6
2583 Male, age 75, right hemisphere 121.9
2409 Female, age 72, unknown 121.5
2241 Male, age 72, unknown 120.9
2665 Male, age 74, both hemispheres 119.6
Superior colliculus
nTPM: 124.6
1796 Male, age 53, unknown 134.7
2261 Male, age 18, unknown 132.4
1995 Male, age 72, unknown 127.5
2087 Female, age 72, unknown 127.2
1913 Female, age 42, unknown 126.7
2668 Female, age 75, unknown 124.1
2587 Male, age 74, left hemisphere 122.0
2664 Male, age 75, both hemispheres 118.6
1839 Male, age 51, unknown 118.1
1895 Male, age 76, right hemisphere 115.1
Ventral tegmental area
nTPM: 132.0
2410 Female, age 72, unknown 139.3
1915 Female, age 42, unknown 137.2
2218 Male, age 76, both hemispheres 131.2
1942 Male, age 51, unknown 129.8
2223 Female, age 72, unknown 129.1
2021 Male, age 53, unknown 125.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 180.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 180.9
Samples: 139

Max nTPM: 356.2
Min nTPM: 84.0
Std nTPM: 44.3
Median nTPM: 171.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 356.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 325.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 304.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 299.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 293.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 285.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 283.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 283.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 260.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 247.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 247.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 246.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 239.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 233.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 230.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 227.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 225.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 225.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 223.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 220.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 219.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 219.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 217.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 216.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 215.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 212.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 209.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 209.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 208.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 207.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 206.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 205.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 203.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 203.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 202.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 199.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 198.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 198.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 198.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 194.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 193.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 193.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 193.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 193.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 192.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 190.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 187.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 187.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 186.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 185.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 185.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 184.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 182.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 182.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 180.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 178.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 178.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 178.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 177.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 176.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 176.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 176.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 175.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 175.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 174.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 173.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 172.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 172.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 172.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 171.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 171.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 171.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 169.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 169.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 168.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 168.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 167.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 167.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 166.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 166.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 165.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 164.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 164.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 164.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 163.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 163.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 163.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 162.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 162.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 162.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 162.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 161.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 161.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 160.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 159.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 159.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 158.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 158.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 157.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 157.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 157.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 155.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 154.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 154.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 154.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 153.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 152.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 151.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 150.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 150.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 150.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 149.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 149.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 147.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 147.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 147.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 146.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 144.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 143.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 140.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 140.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 138.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 138.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 137.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 134.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 133.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 132.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 131.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 129.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 127.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 122.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 121.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 121.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 116.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 115.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 100.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 99.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 84.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 133.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 133.7
FF:10158-103A5 76 years, female 133.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 105.9
Pig sample Sample description nTPM
Midbrain
nTPM: 105.9
Samples: 4

Max nTPM: 178.5
Min nTPM: 68.5
Sample A Female 178.5
Sample B Female 87.9
Sample C Male 88.7
Sample D Male 68.5
Periaqueductal gray
nTPM: 80.1
Samples: 3

Max nTPM: 91.7
Min nTPM: 74.3
Sample B Female 74.3
Sample C Male 91.7
Sample D Male 74.3
Substantia nigra
nTPM: 102.5
Samples: 4

Max nTPM: 118.5
Min nTPM: 75.2
Sample A Female 118.5
Sample B Female 75.2
Sample C Male 111.7
Sample D Male 104.6
Superior colliculi
nTPM: 89.5
Samples: 4

Max nTPM: 105.5
Min nTPM: 57.0
Sample A Female 99.1
Sample B Female 57.0
Sample C Male 105.5
Sample D Male 96.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 88.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 88.1
Samples: 4

Max nTPM: 102.4
Min nTPM: 76.8
Sample A Male 102.4
Sample B Male 82.8
Sample C Female 76.8
Sample D Female 90.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.8
68269664 Antisense, RP_041129_02_A05, Mouse strain C57BL/6J (56 days, male) 6.8

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