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FKBP8
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:406.1 nTPM
HPA:406.1 nTPM
FANTOM5:285.7 Scaled Tags Per Million
Pig:232.2 nTPM
Allen mouse:0.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 406.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 352.3
2301 Female, age 85, both hemispheres 363.0
2188 Female, age 91, both hemispheres 356.5
2090 Male, age 80, both hemispheres 346.0
1984 Male, age 76, both hemispheres 343.7
Dorsal cochlear nucleus
nTPM: 372.0
2802 Male, age 74, right hemisphere 393.5
2370 Male, age 61, both hemispheres 378.8
2058 Male, age 76, both hemispheres 369.7
2187 Female, age 91, both hemispheres 369.6
2378 Male, age 80, both hemispheres 348.6
Dorsal tegmental nucleus
nTPM: 365.7
2083 Male, age 80, both hemispheres 383.9
2358 Male, age 61, both hemispheres 369.8
1936 Male, age 76, left hemisphere 356.7
2326 Male, age 74, both hemispheres 352.4
Dorsolateral tegmental area
nTPM: 357.3
2654 Male, age 80, both hemispheres 391.3
2141 Male, age 76, both hemispheres 359.7
2751 Female, age 85, both hemispheres 355.1
2337 Male, age 61, both hemispheres 341.8
2360 Male, age 74, both hemispheres 338.7
Kolliker-Fuse nucleus
nTPM: 368.0
2793 Female, age 91, left hemisphere 395.1
2163 Male, age 80, both hemispheres 369.2
2315 Male, age 76, right hemisphere 339.6
Lateral lemniscal nuclei
nTPM: 385.2
2169 Male, age 76, both hemispheres 413.9
2746 Female, age 85, left hemisphere 393.0
2453 Male, age 74, right hemisphere 390.5
2036 Male, age 80, both hemispheres 364.8
2320 Female, age 91, left hemisphere 363.6
Lateral parabrachial nucleus
nTPM: 377.4
2790 Male, age 61, both hemispheres 405.4
2139 Female, age 85, right hemisphere 398.9
2013 Male, age 80, both hemispheres 364.8
2792 Male, age 76, both hemispheres 340.3
Lateral vestibular nucleus
nTPM: 374.8
2311 Male, age 80, both hemispheres 377.3
2184 Male, age 76, both hemispheres 372.3
Locus coeruleus
nTPM: 371.3
2123 Female, age 91, both hemispheres 384.3
2720 Male, age 74, both hemispheres 382.6
2317 Female, age 72, unknown 379.4
2162 Male, age 80, both hemispheres 376.6
1980 Male, age 76, both hemispheres 370.6
2014 Male, age 55, unknown 365.4
2788 Male, age 74, unknown 340.1
Medial olivary nucleus
nTPM: 341.5
2138 Female, age 91, both hemispheres 361.3
2851 Male, age 80, both hemispheres 352.8
1943 Male, age 61, both hemispheres 334.7
1962 Male, age 76, both hemispheres 317.0
Medial parabrachial nucleus
nTPM: 376.1
2156 Male, age 61, both hemispheres 392.9
2170 Female, age 91, both hemispheres 379.2
2786 Male, age 76, both hemispheres 373.2
2854 Male, age 80, both hemispheres 371.4
2463 Female, age 85, right hemisphere 363.6
Medial periolivary nuclei
nTPM: 387.0
2063 Male, age 76, both hemispheres 438.0
2171 Female, age 85, both hemispheres 427.3
2791 Male, age 74, right hemisphere 365.0
2458 Female, age 91, both hemispheres 358.0
2081 Male, age 80, both hemispheres 346.9
Motor facial nucleus
nTPM: 399.0
2062 Male, age 76, both hemispheres 442.8
2697 Female, age 85, both hemispheres 409.6
2795 Female, age 91, both hemispheres 409.3
2327 Male, age 80, both hemispheres 393.3
2365 Male, age 74, right hemisphere 377.2
2126 Male, age 61, both hemispheres 361.9
Motor trigeminal nucleus
nTPM: 383.7
2560 Male, age 74, both hemispheres 402.0
2335 Male, age 61, both hemispheres 396.5
2309 Male, age 76, both hemispheres 380.4
2079 Male, age 80, both hemispheres 372.1
2321 Female, age 91, both hemispheres 367.5
Nuclei of the trapezoid body
nTPM: 406.1
1983 Male, age 76, both hemispheres 429.4
2735 Female, age 85, both hemispheres 428.9
2159 Male, age 61, both hemispheres 409.4
2368 Female, age 91, both hemispheres 381.6
2166 Male, age 80, both hemispheres 381.4
Paramedian reticular nucleus
nTPM: 368.6
2050 Female, age 85, both hemispheres 395.3
2313 Male, age 61, both hemispheres 383.5
2057 Male, age 80, both hemispheres 374.7
2052 Male, age 76, both hemispheres 320.7
Pontine nuclei
nTPM: 402.7
2787 Female, age 85, both hemispheres 495.5
1863 Male, age 55, unknown 434.9
1968 Male, age 76, left hemisphere 434.3
2727 Male, age 61, right hemisphere 398.2
2109 Female, age 72, unknown 386.2
2115 Male, age 80, left hemisphere 365.6
2454 Male, age 74, left hemisphere 354.0
2319 Female, age 91, both hemispheres 353.1
Pontine raphe nucleus
nTPM: 393.3
2122 Female, age 85, midline 397.2
2853 Male, age 76, midline 389.5
Posteroventral cochlear nucleus
nTPM: 359.5
2752 Female, age 85, both hemispheres 393.1
2371 Male, age 61, both hemispheres 384.0
2070 Male, age 76, both hemispheres 364.6
2135 Female, age 91, both hemispheres 334.5
2341 Male, age 80, both hemispheres 321.5
Principal sensory trigeminal nucleus
nTPM: 385.0
2158 Male, age 61, both hemispheres 432.6
2008 Male, age 80, left hemisphere 389.5
2324 Male, age 76, both hemispheres 363.5
2367 Female, age 91, left hemisphere 354.5
Reticular pontine nucleus, caudal
nTPM: 383.4
2332 Male, age 80, right hemisphere 410.1
2092 Male, age 76, both hemispheres 386.4
2559 Male, age 74, both hemispheres 370.7
2457 Female, age 91, both hemispheres 366.5
Reticular pontine nucleus, oral
nTPM: 371.1
2012 Female, age 85, both hemispheres 383.2
2167 Male, age 76, both hemispheres 371.1
2366 Female, age 91, both hemispheres 370.8
1939 Male, age 80, both hemispheres 365.2
2361 Male, age 74, both hemispheres 365.1
Reticulotegmental nucleus
nTPM: 378.5
2325 Male, age 76, both hemispheres 391.4
2452 Male, age 74, both hemispheres 387.1
2322 Female, age 91, both hemispheres 372.8
2333 Male, age 80, both hemispheres 362.5
Spinal trigeminal nucleus, oral
nTPM: 374.6
1978 Male, age 76, both hemispheres 382.8
2164 Male, age 80, both hemispheres 376.1
2737 Female, age 85, both hemispheres 364.8
Subcoeruleus area
nTPM: 378.3
2323 Female, age 91, left hemisphere 398.8
2089 Male, age 76, left hemisphere 382.4
1958 Male, age 80, both hemispheres 381.7
2451 Male, age 74, both hemispheres 381.2
2369 Female, age 85, left hemisphere 347.5
Superior olive
nTPM: 389.6
1875 Female, age 85, both hemispheres 413.8
2561 Female, age 91, both hemispheres 393.4
2020 Male, age 76, both hemispheres 392.4
2329 Male, age 80, right hemisphere 387.2
2364 Male, age 74, right hemisphere 361.1
Superior vestibular nucleus
nTPM: 354.7
2015 Male, age 80, both hemispheres 371.7
2061 Male, age 76, both hemispheres 357.3
2383 Male, age 74, both hemispheres 335.2
Ventral periolivary nuclei
nTPM: 389.4
2165 Male, age 80, both hemispheres 408.4
2130 Female, age 85, both hemispheres 404.1
2794 Female, age 91, left hemisphere 374.4
2023 Male, age 76, both hemispheres 370.8
Ventrolateral tegmental area, A5 NE cell group
nTPM: 377.2
1959 Male, age 76, both hemispheres 394.7
2449 Male, age 74, both hemispheres 386.7
2161 Male, age 80, both hemispheres 384.4
2840 Female, age 85, both hemispheres 372.2
2456 Female, age 91, both hemispheres 363.3
2359 Male, age 61, both hemispheres 362.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 285.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 177.4
FF:10182-103D2 60 years, female 191.1
FF:10165-103B3 76 years, female 163.7
Pons
Scaled Tags Per Million: 285.7
FF:10033-101E6 18-54 years, mixed 285.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 232.2
Pig sample Sample description nTPM
Pons
nTPM: 232.2
Samples: 4

Max nTPM: 318.9
Min nTPM: 172.2
Sample A Female 318.9
Sample B Female 172.2
Sample C Male 207.2
Sample D Male 230.6

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 0.6
71487112 Antisense, RP_050913_01_C07, Mouse strain C57BL/6J (56 days, male) 0.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.