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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:165.0 nTPM
HPA:165.0 nTPM
GTEx:165.2 nTPM
FANTOM5:144.2 Scaled Tags Per Million
Pig:173.8 nTPM
Mouse:128.3 nTPM
Allen mouse:15.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 165.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 153.7
2586 Male, age 75, left hemisphere 172.3
2019 Male, age 18, unknown 164.1
1870 Female, age 42, unknown 162.0
2411 Female, age 72, unknown 157.9
2828 Female, age 72, unknown 156.3
1833 Male, age 53, unknown 152.2
1827 Male, age 72, unknown 148.8
1830 Male, age 51, unknown 148.1
2666 Male, age 74, left hemisphere 139.6
2219 Male, age 76, both hemispheres 135.8
Dorsal raphe nucleus
nTPM: 142.5
2750 Male, age 76, both hemispheres 154.2
1828 Male, age 53, unknown 148.6
2016 Female, age 72, unknown 140.6
2298 Female, age 72, unknown 138.1
2047 Male, age 72, unknown 130.8
Inferior colliculus
nTPM: 146.1
1890 Male, age 53, unknown 148.8
2097 Female, age 72, unknown 148.5
1848 Female, age 42, unknown 144.1
2849 Male, age 72, unknown 143.1
Median raphe nucleus
nTPM: 131.6
2220 Male, age 76, midline 131.6
Pedunculopontine tegmental nucleus
nTPM: 139.8
2334 Male, age 80, both hemispheres 144.9
1921 Female, age 85, both hemispheres 144.3
2338 Male, age 61, both hemispheres 130.1
Periaquaductal grey, anterior
nTPM: 143.6
2502 Female, age 75, unknown 151.7
1947 Male, age 18, unknown 139.9
1795 Male, age 51, unknown 139.2
Periaquaductal grey, dorsal
nTPM: 136.2
2464 Female, age 72, unknown 142.1
1840 Male, age 53, unknown 135.2
2850 Male, age 76, both hemispheres 135.1
1831 Male, age 72, unknown 132.5
Periaquaductal grey, lateral
nTPM: 132.7
2053 Male, age 18, unknown 135.7
2140 Male, age 76, both hemispheres 132.4
2272 Male, age 74, both hemispheres 129.9
Pretectal area
nTPM: 150.7
2007 Male, age 72, unknown 166.1
1817 Female, age 42, unknown 165.6
1815 Male, age 53, unknown 165.3
1944 Female, age 72, unknown 159.9
1816 Male, age 51, unknown 158.7
2667 Female, age 75, unknown 152.3
2316 Male, age 76, right hemisphere 142.9
2407 Male, age 75, both hemispheres 141.8
2825 Male, age 18, unknown 138.2
2273 Male, age 74, both hemispheres 133.9
2224 Female, age 72, unknown 132.8
Red nucleus
nTPM: 165.0
2503 Female, age 72, unknown 174.3
2769 Male, age 72, unknown 173.6
1904 Male, age 53, unknown 172.3
2227 Male, age 72, unknown 171.8
2785 Male, age 18, unknown 170.4
1865 Male, age 51, unknown 169.8
1821 Female, age 72, unknown 167.0
2588 Male, age 74, left hemisphere 163.9
1954 Female, age 42, unknown 163.1
2823 Male, age 76, right hemisphere 161.2
2725 Female, age 75, unknown 149.9
2584 Male, age 75, left hemisphere 142.4
Substantia nigra
nTPM: 138.7
1889 Female, age 72, unknown 163.4
2583 Male, age 75, right hemisphere 147.9
1851 Male, age 51, unknown 141.7
2590 Female, age 75, unknown 138.9
2699 Male, age 18, unknown 137.9
2665 Male, age 74, both hemispheres 137.7
2409 Female, age 72, unknown 136.8
1916 Female, age 42, unknown 132.6
1941 Male, age 53, unknown 125.9
2241 Male, age 72, unknown 124.4
Superior colliculus
nTPM: 152.5
1995 Male, age 72, unknown 169.6
1913 Female, age 42, unknown 166.8
2087 Female, age 72, unknown 154.3
2668 Female, age 75, unknown 152.9
1895 Male, age 76, right hemisphere 151.5
2261 Male, age 18, unknown 149.5
2664 Male, age 75, both hemispheres 149.3
1796 Male, age 53, unknown 144.9
1839 Male, age 51, unknown 143.8
2587 Male, age 74, left hemisphere 141.9
Ventral tegmental area
nTPM: 140.1
2410 Female, age 72, unknown 148.7
2223 Female, age 72, unknown 147.6
1942 Male, age 51, unknown 140.2
1915 Female, age 42, unknown 137.0
2021 Male, age 53, unknown 135.3
2218 Male, age 76, both hemispheres 132.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 165.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 165.2
Samples: 139

Max nTPM: 302.0
Min nTPM: 76.4
Std nTPM: 38.9
Median nTPM: 160.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 302.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 297.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 280.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 255.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 248.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 240.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 239.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 234.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 228.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 226.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 225.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 223.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 220.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 217.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 211.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 209.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 208.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 207.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 206.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 204.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 203.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 201.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 201.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 201.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 199.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 197.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 196.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 192.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 190.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 189.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 189.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 187.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 186.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 183.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 182.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 181.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 179.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 179.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 179.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 178.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 176.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 175.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 175.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 175.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 175.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 174.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 174.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 174.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 174.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 174.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 174.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 172.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 172.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 172.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 171.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 169.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 167.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 165.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 165.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 165.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 164.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 164.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 164.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 163.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 163.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 162.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 162.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 161.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 161.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 160.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 160.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 160.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 159.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 158.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 158.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 158.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 157.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 156.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 155.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 155.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 155.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 155.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 155.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 154.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 154.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 153.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 153.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 151.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 149.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 148.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 147.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 147.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 146.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 146.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 145.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 145.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 144.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 144.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 143.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 143.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 141.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 141.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 141.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 140.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 140.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 140.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 140.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 137.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 136.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 136.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 136.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 136.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 135.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 134.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 133.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 131.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 130.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 129.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 128.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 128.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 126.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 124.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 124.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 123.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 122.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 118.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 118.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 109.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 106.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 106.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 101.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 100.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 97.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 92.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 87.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 76.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 144.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 144.2
FF:10158-103A5 76 years, female 144.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 173.8
Pig sample Sample description nTPM
Midbrain
nTPM: 173.8
Samples: 4

Max nTPM: 298.8
Min nTPM: 110.4
Sample A Female 298.8
Sample B Female 155.0
Sample C Male 110.4
Sample D Male 131.0
Periaqueductal gray
nTPM: 116.2
Samples: 3

Max nTPM: 129.2
Min nTPM: 104.3
Sample B Female 129.2
Sample C Male 115.0
Sample D Male 104.3
Substantia nigra
nTPM: 154.3
Samples: 4

Max nTPM: 195.1
Min nTPM: 114.4
Sample A Female 169.2
Sample B Female 114.4
Sample C Male 138.5
Sample D Male 195.1
Superior colliculi
nTPM: 144.7
Samples: 4

Max nTPM: 192.4
Min nTPM: 75.9
Sample A Female 192.4
Sample B Female 75.9
Sample C Male 139.9
Sample D Male 170.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 128.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.3
Samples: 4

Max nTPM: 144.0
Min nTPM: 120.4
Sample A Male 144.0
Sample B Male 121.0
Sample C Female 120.4
Sample D Female 127.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.6
69735299 Antisense, RP_050503_02_E05, Mouse strain C57BL/6J (56 days, male) 15.6

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