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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:129.1 nTPM
HPA:129.1 nTPM
GTEx:142.0 nTPM
FANTOM5:7.5 Scaled Tags Per Million
Pig:77.4 nTPM
Mouse:107.1 nTPM
Allen mouse:3.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 129.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 117.4
1827 Male, age 72, unknown 123.1
2019 Male, age 18, unknown 123.0
2586 Male, age 75, left hemisphere 122.5
2666 Male, age 74, left hemisphere 119.1
1870 Female, age 42, unknown 116.5
2411 Female, age 72, unknown 116.1
1833 Male, age 53, unknown 114.5
2828 Female, age 72, unknown 114.0
2219 Male, age 76, both hemispheres 112.7
1830 Male, age 51, unknown 112.4
Dorsal raphe nucleus
nTPM: 118.5
2298 Female, age 72, unknown 122.5
1828 Male, age 53, unknown 121.5
2047 Male, age 72, unknown 118.1
2016 Female, age 72, unknown 115.7
2750 Male, age 76, both hemispheres 114.7
Inferior colliculus
nTPM: 117.9
2097 Female, age 72, unknown 123.4
1890 Male, age 53, unknown 118.2
1848 Female, age 42, unknown 116.5
2849 Male, age 72, unknown 113.6
Median raphe nucleus
nTPM: 116.0
2220 Male, age 76, midline 116.0
Pedunculopontine tegmental nucleus
nTPM: 121.8
1921 Female, age 85, both hemispheres 125.5
2334 Male, age 80, both hemispheres 124.5
2338 Male, age 61, both hemispheres 115.5
Periaquaductal grey, anterior
nTPM: 120.9
1947 Male, age 18, unknown 122.9
1795 Male, age 51, unknown 120.9
2502 Female, age 75, unknown 118.7
Periaquaductal grey, dorsal
nTPM: 117.3
2850 Male, age 76, both hemispheres 122.1
1840 Male, age 53, unknown 117.1
1831 Male, age 72, unknown 116.2
2464 Female, age 72, unknown 113.6
Periaquaductal grey, lateral
nTPM: 118.0
2053 Male, age 18, unknown 119.5
2140 Male, age 76, both hemispheres 119.3
2272 Male, age 74, both hemispheres 115.3
Pretectal area
nTPM: 126.0
1816 Male, age 51, unknown 137.8
1944 Female, age 72, unknown 136.1
1817 Female, age 42, unknown 133.1
1815 Male, age 53, unknown 130.0
2007 Male, age 72, unknown 127.0
2667 Female, age 75, unknown 124.8
2273 Male, age 74, both hemispheres 124.4
2224 Female, age 72, unknown 124.1
2316 Male, age 76, right hemisphere 117.6
2407 Male, age 75, both hemispheres 115.7
2825 Male, age 18, unknown 115.5
Red nucleus
nTPM: 116.5
1821 Female, age 72, unknown 131.7
2725 Female, age 75, unknown 121.7
2785 Male, age 18, unknown 118.9
2823 Male, age 76, right hemisphere 117.0
1954 Female, age 42, unknown 116.7
1865 Male, age 51, unknown 115.5
2584 Male, age 75, left hemisphere 114.5
1904 Male, age 53, unknown 114.2
2227 Male, age 72, unknown 113.7
2503 Female, age 72, unknown 112.9
2769 Male, age 72, unknown 110.8
2588 Male, age 74, left hemisphere 110.4
Substantia nigra
nTPM: 129.1
2241 Male, age 72, unknown 144.5
1916 Female, age 42, unknown 138.0
2409 Female, age 72, unknown 134.9
1851 Male, age 51, unknown 133.5
1889 Female, age 72, unknown 130.7
1941 Male, age 53, unknown 129.6
2699 Male, age 18, unknown 121.0
2590 Female, age 75, unknown 120.5
2583 Male, age 75, right hemisphere 119.7
2665 Male, age 74, both hemispheres 119.0
Superior colliculus
nTPM: 119.6
2087 Female, age 72, unknown 126.2
2261 Male, age 18, unknown 123.4
2668 Female, age 75, unknown 123.2
2587 Male, age 74, left hemisphere 121.3
1796 Male, age 53, unknown 118.4
1913 Female, age 42, unknown 117.7
1895 Male, age 76, right hemisphere 117.6
2664 Male, age 75, both hemispheres 117.0
1995 Male, age 72, unknown 116.6
1839 Male, age 51, unknown 114.7
Ventral tegmental area
nTPM: 119.7
1915 Female, age 42, unknown 125.8
2410 Female, age 72, unknown 122.4
2218 Male, age 76, both hemispheres 121.6
1942 Male, age 51, unknown 117.7
2021 Male, age 53, unknown 117.2
2223 Female, age 72, unknown 113.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 142.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 142.0
Samples: 139

Max nTPM: 264.1
Min nTPM: 70.0
Std nTPM: 37.1
Median nTPM: 137.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 264.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 241.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 237.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 236.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 234.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 223.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 220.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 217.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 209.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 207.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 206.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 200.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 196.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 189.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 189.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 187.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 183.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 183.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 183.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 176.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 175.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 174.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 173.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 171.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 170.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 170.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 168.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 166.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 166.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 165.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 164.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 163.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 161.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 161.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 160.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 159.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 158.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 158.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 157.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 157.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 157.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 156.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 154.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 154.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 154.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 153.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 152.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 151.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 151.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 151.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 150.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 148.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 148.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 147.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 146.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 146.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 146.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 145.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 145.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 144.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 143.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 143.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 143.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 142.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 141.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 140.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 138.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 138.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 138.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 137.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 137.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 136.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 131.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 131.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 131.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 130.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 129.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 129.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 129.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 129.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 129.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 129.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 128.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 128.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 127.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 127.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 126.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 126.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 126.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 126.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 126.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 125.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 125.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 124.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 123.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 123.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 123.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 123.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 122.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 122.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 122.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 121.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 121.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 121.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 120.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 118.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 117.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 116.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 116.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 115.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 113.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 113.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 112.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 111.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 109.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 108.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 108.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 106.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 104.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 102.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 101.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 101.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 100.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 100.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 100.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 96.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 95.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 92.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 86.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 84.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 79.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 76.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 73.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 73.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 72.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 70.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 7.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 7.5
FF:10158-103A5 76 years, female 7.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 77.4
Pig sample Sample description nTPM
Midbrain
nTPM: 69.4
Samples: 4

Max nTPM: 82.4
Min nTPM: 56.8
Sample A Female 68.5
Sample B Female 56.8
Sample C Male 82.4
Sample D Male 69.7
Periaqueductal gray
nTPM: 52.2
Samples: 3

Max nTPM: 57.9
Min nTPM: 45.4
Sample B Female 45.4
Sample C Male 57.9
Sample D Male 53.4
Substantia nigra
nTPM: 64.0
Samples: 4

Max nTPM: 83.0
Min nTPM: 49.8
Sample A Female 83.0
Sample B Female 59.4
Sample C Male 63.6
Sample D Male 49.8
Superior colliculi
nTPM: 77.4
Samples: 4

Max nTPM: 85.7
Min nTPM: 70.3
Sample A Female 85.7
Sample B Female 70.3
Sample C Male 81.3
Sample D Male 72.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 107.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.1
Samples: 4

Max nTPM: 109.5
Min nTPM: 104.5
Sample A Male 105.5
Sample B Male 109.5
Sample C Female 104.5
Sample D Female 108.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.5
564750 Antisense, RP_040826_01_C05, Mouse strain C57BL/6J (56 days, male) 3.5

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