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MRPL27
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  • MRPL27
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:105.7 nTPM
HPA:105.7 nTPM
GTEx:94.1 nTPM
FANTOM5:44.7 Scaled Tags Per Million
Pig:37.8 nTPM
Mouse:109.8 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 105.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 102.5
2019 Male, age 18, unknown 106.7
1827 Male, age 72, unknown 106.2
2411 Female, age 72, unknown 104.6
2828 Female, age 72, unknown 103.0
1870 Female, age 42, unknown 102.7
2219 Male, age 76, both hemispheres 100.7
1830 Male, age 51, unknown 100.5
1833 Male, age 53, unknown 100.5
2666 Male, age 74, left hemisphere 100.3
2586 Male, age 75, left hemisphere 100.1
Dorsal raphe nucleus
nTPM: 103.8
2298 Female, age 72, unknown 106.5
1828 Male, age 53, unknown 105.1
2750 Male, age 76, both hemispheres 103.7
2016 Female, age 72, unknown 102.3
2047 Male, age 72, unknown 101.2
Inferior colliculus
nTPM: 102.9
2097 Female, age 72, unknown 104.9
1890 Male, age 53, unknown 103.7
2849 Male, age 72, unknown 101.6
1848 Female, age 42, unknown 101.5
Median raphe nucleus
nTPM: 102.3
2220 Male, age 76, midline 102.3
Pedunculopontine tegmental nucleus
nTPM: 103.3
2334 Male, age 80, both hemispheres 104.2
1921 Female, age 85, both hemispheres 103.5
2338 Male, age 61, both hemispheres 102.1
Periaquaductal grey, anterior
nTPM: 102.9
1947 Male, age 18, unknown 103.6
1795 Male, age 51, unknown 103.3
2502 Female, age 75, unknown 101.8
Periaquaductal grey, dorsal
nTPM: 101.7
1840 Male, age 53, unknown 103.4
2464 Female, age 72, unknown 102.7
1831 Male, age 72, unknown 100.8
2850 Male, age 76, both hemispheres 100.0
Periaquaductal grey, lateral
nTPM: 102.6
2272 Male, age 74, both hemispheres 106.2
2140 Male, age 76, both hemispheres 100.9
2053 Male, age 18, unknown 100.6
Pretectal area
nTPM: 105.7
2007 Male, age 72, unknown 110.5
1816 Male, age 51, unknown 109.9
1817 Female, age 42, unknown 108.9
1944 Female, age 72, unknown 108.7
2273 Male, age 74, both hemispheres 108.5
1815 Male, age 53, unknown 107.5
2667 Female, age 75, unknown 105.2
2224 Female, age 72, unknown 103.3
2825 Male, age 18, unknown 102.3
2407 Male, age 75, both hemispheres 100.0
2316 Male, age 76, right hemisphere 98.5
Red nucleus
nTPM: 103.5
1821 Female, age 72, unknown 106.5
2725 Female, age 75, unknown 105.7
2785 Male, age 18, unknown 105.4
2823 Male, age 76, right hemisphere 104.5
1865 Male, age 51, unknown 104.3
1954 Female, age 42, unknown 103.8
2503 Female, age 72, unknown 103.7
2227 Male, age 72, unknown 102.5
1904 Male, age 53, unknown 102.3
2588 Male, age 74, left hemisphere 102.3
2769 Male, age 72, unknown 102.2
2584 Male, age 75, left hemisphere 99.5
Substantia nigra
nTPM: 104.8
1916 Female, age 42, unknown 111.3
1889 Female, age 72, unknown 109.8
1851 Male, age 51, unknown 106.3
1941 Male, age 53, unknown 105.8
2241 Male, age 72, unknown 104.8
2409 Female, age 72, unknown 103.6
2699 Male, age 18, unknown 102.4
2590 Female, age 75, unknown 102.3
2665 Male, age 74, both hemispheres 101.3
2583 Male, age 75, right hemisphere 101.0
Superior colliculus
nTPM: 103.6
2087 Female, age 72, unknown 106.2
1895 Male, age 76, right hemisphere 105.3
2668 Female, age 75, unknown 105.0
2587 Male, age 74, left hemisphere 104.8
2261 Male, age 18, unknown 104.2
1796 Male, age 53, unknown 104.1
1995 Male, age 72, unknown 102.7
1913 Female, age 42, unknown 101.3
2664 Male, age 75, both hemispheres 101.2
1839 Male, age 51, unknown 101.1
Ventral tegmental area
nTPM: 103.6
2410 Female, age 72, unknown 108.2
2218 Male, age 76, both hemispheres 106.9
1915 Female, age 42, unknown 104.6
1942 Male, age 51, unknown 101.6
2223 Female, age 72, unknown 100.5
2021 Male, age 53, unknown 99.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 94.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 94.1
Samples: 139

Max nTPM: 188.9
Min nTPM: 41.9
Std nTPM: 24.5
Median nTPM: 91.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 188.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 174.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 159.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 148.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 142.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 141.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 135.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 135.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 132.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 132.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 131.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 127.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 127.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 126.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 124.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 123.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 121.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 118.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 118.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 117.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 116.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 115.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 114.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 113.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 113.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 112.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 111.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 111.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 109.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 108.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 107.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 107.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 107.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 107.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 106.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 106.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 105.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 104.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 102.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 101.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 101.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 100.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 100.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 100.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 100.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 99.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 99.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 99.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 98.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 98.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 98.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 98.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 98.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 98.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 97.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 97.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 97.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 97.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 96.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 96.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 94.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 94.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 93.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 93.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 92.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 91.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 91.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 91.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 91.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 89.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 88.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 88.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 88.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 87.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 87.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 87.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 86.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 85.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 85.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 84.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 84.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 84.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 83.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 83.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 83.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 83.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 82.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 82.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 81.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 81.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 81.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 79.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 79.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 79.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 79.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 78.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 78.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 78.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 77.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 77.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 76.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 76.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 76.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 75.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 75.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 75.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 75.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 74.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 74.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 73.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 70.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 70.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 67.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 67.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 66.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 64.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 63.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 63.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 61.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 58.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 58.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 47.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 43.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 43.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 41.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 44.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 44.7
FF:10158-103A5 76 years, female 44.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 37.8
Pig sample Sample description nTPM
Midbrain
nTPM: 36.8
Samples: 4

Max nTPM: 44.1
Min nTPM: 28.5
Sample A Female 44.1
Sample B Female 39.4
Sample C Male 35.3
Sample D Male 28.5
Periaqueductal gray
nTPM: 29.4
Samples: 3

Max nTPM: 32.3
Min nTPM: 24.7
Sample B Female 32.3
Sample C Male 31.2
Sample D Male 24.7
Substantia nigra
nTPM: 34.7
Samples: 4

Max nTPM: 43.2
Min nTPM: 28.0
Sample A Female 43.2
Sample B Female 28.0
Sample C Male 34.4
Sample D Male 33.2
Superior colliculi
nTPM: 37.8
Samples: 4

Max nTPM: 45.8
Min nTPM: 26.7
Sample A Female 45.8
Sample B Female 36.5
Sample C Male 42.3
Sample D Male 26.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 109.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 109.8
Samples: 4

Max nTPM: 115.8
Min nTPM: 104.9
Sample A Male 115.8
Sample B Male 104.9
Sample C Female 105.1
Sample D Female 113.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
68744785 Antisense, RP_050208_01_F06, Mouse strain C57BL/6J (56 days, male) 0.7

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