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  • ATP5F1B
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:242.9 nTPM
HPA:242.9 nTPM
GTEx:318.2 nTPM
FANTOM5:228.5 Scaled Tags Per Million
Pig:356.4 nTPM
Mouse:1423.8 nTPM
Allen mouse:25.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 242.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 201.3
2019 Male, age 18, unknown 252.8
2411 Female, age 72, unknown 224.5
2219 Male, age 76, both hemispheres 223.8
1827 Male, age 72, unknown 220.8
2828 Female, age 72, unknown 197.8
1870 Female, age 42, unknown 191.3
1833 Male, age 53, unknown 187.9
2666 Male, age 74, left hemisphere 178.5
1830 Male, age 51, unknown 174.0
2586 Male, age 75, left hemisphere 161.5
Dorsal raphe nucleus
nTPM: 218.7
2298 Female, age 72, unknown 267.3
1828 Male, age 53, unknown 228.4
2750 Male, age 76, both hemispheres 209.7
2047 Male, age 72, unknown 205.6
2016 Female, age 72, unknown 182.4
Inferior colliculus
nTPM: 217.0
2097 Female, age 72, unknown 267.9
1890 Male, age 53, unknown 219.6
1848 Female, age 42, unknown 202.7
2849 Male, age 72, unknown 177.7
Median raphe nucleus
nTPM: 203.3
2220 Male, age 76, midline 203.3
Pedunculopontine tegmental nucleus
nTPM: 214.4
1921 Female, age 85, both hemispheres 232.1
2334 Male, age 80, both hemispheres 217.9
2338 Male, age 61, both hemispheres 193.2
Periaquaductal grey, anterior
nTPM: 207.1
1947 Male, age 18, unknown 215.9
1795 Male, age 51, unknown 208.3
2502 Female, age 75, unknown 197.2
Periaquaductal grey, dorsal
nTPM: 184.9
2464 Female, age 72, unknown 188.6
1840 Male, age 53, unknown 184.9
1831 Male, age 72, unknown 183.4
2850 Male, age 76, both hemispheres 182.5
Periaquaductal grey, lateral
nTPM: 199.1
2272 Male, age 74, both hemispheres 242.3
2053 Male, age 18, unknown 178.3
2140 Male, age 76, both hemispheres 176.8
Pretectal area
nTPM: 239.7
1816 Male, age 51, unknown 289.7
2007 Male, age 72, unknown 289.5
1817 Female, age 42, unknown 287.8
1944 Female, age 72, unknown 280.1
2667 Female, age 75, unknown 256.5
2273 Male, age 74, both hemispheres 245.3
1815 Male, age 53, unknown 242.7
2224 Female, age 72, unknown 214.3
2316 Male, age 76, right hemisphere 195.2
2825 Male, age 18, unknown 181.3
2407 Male, age 75, both hemispheres 154.7
Red nucleus
nTPM: 213.1
1821 Female, age 72, unknown 267.8
2785 Male, age 18, unknown 235.7
2725 Female, age 75, unknown 234.5
2503 Female, age 72, unknown 226.5
1954 Female, age 42, unknown 211.2
2823 Male, age 76, right hemisphere 210.3
1904 Male, age 53, unknown 207.0
1865 Male, age 51, unknown 205.9
2769 Male, age 72, unknown 205.6
2227 Male, age 72, unknown 205.4
2588 Male, age 74, left hemisphere 186.8
2584 Male, age 75, left hemisphere 160.4
Substantia nigra
nTPM: 242.9
1916 Female, age 42, unknown 300.5
1889 Female, age 72, unknown 273.4
1851 Male, age 51, unknown 271.3
1941 Male, age 53, unknown 264.3
2241 Male, age 72, unknown 259.6
2665 Male, age 74, both hemispheres 236.4
2409 Female, age 72, unknown 235.2
2699 Male, age 18, unknown 209.4
2590 Female, age 75, unknown 204.5
2583 Male, age 75, right hemisphere 174.8
Superior colliculus
nTPM: 204.0
2087 Female, age 72, unknown 262.7
2261 Male, age 18, unknown 219.3
1895 Male, age 76, right hemisphere 219.1
1796 Male, age 53, unknown 216.9
2587 Male, age 74, left hemisphere 210.5
2668 Female, age 75, unknown 200.5
1913 Female, age 42, unknown 192.1
1839 Male, age 51, unknown 188.8
1995 Male, age 72, unknown 184.8
2664 Male, age 75, both hemispheres 145.2
Ventral tegmental area
nTPM: 225.4
2410 Female, age 72, unknown 281.8
1915 Female, age 42, unknown 254.8
2218 Male, age 76, both hemispheres 254.4
1942 Male, age 51, unknown 200.0
2223 Female, age 72, unknown 184.6
2021 Male, age 53, unknown 176.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 318.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 318.2
Samples: 139

Max nTPM: 864.4
Min nTPM: 130.1
Std nTPM: 137.8
Median nTPM: 279.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 864.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 850.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 785.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 694.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 632.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 628.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 628.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 547.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 525.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 513.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 510.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 501.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 498.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 486.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 483.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 479.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 478.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 469.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 466.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 459.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 457.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 452.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 446.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 443.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 438.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 432.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 431.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 428.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 426.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 414.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 410.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 406.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 405.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 404.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 392.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 388.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 375.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 372.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 369.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 369.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 368.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 355.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 351.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 347.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 343.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 340.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 335.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 329.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 323.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 313.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 313.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 312.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 311.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 307.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 305.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 305.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 305.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 302.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 299.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 298.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 295.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 293.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 291.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 291.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 290.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 289.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 284.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 283.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 281.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 279.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 278.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 277.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 276.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 275.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 273.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 272.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 270.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 268.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 267.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 265.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 262.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 261.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 261.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 259.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 258.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 255.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 253.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 246.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 245.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 244.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 242.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 242.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 241.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 240.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 239.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 237.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 237.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 236.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 231.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 230.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 226.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 224.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 222.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 221.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 219.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 218.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 216.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 216.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 215.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 214.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 213.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 212.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 208.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 207.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 207.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 202.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 198.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 197.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 196.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 196.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 195.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 194.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 193.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 190.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 187.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 185.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 183.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 177.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 176.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 176.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 165.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 165.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 163.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 154.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 144.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 144.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 141.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 140.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 130.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 228.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 228.5
FF:10158-103A5 76 years, female 228.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 356.4
Pig sample Sample description nTPM
Midbrain
nTPM: 298.4
Samples: 4

Max nTPM: 411.2
Min nTPM: 243.6
Sample A Female 244.5
Sample B Female 243.6
Sample C Male 411.2
Sample D Male 294.2
Periaqueductal gray
nTPM: 208.8
Samples: 3

Max nTPM: 237.2
Min nTPM: 162.7
Sample B Female 226.6
Sample C Male 237.2
Sample D Male 162.7
Substantia nigra
nTPM: 263.6
Samples: 4

Max nTPM: 374.5
Min nTPM: 175.8
Sample A Female 374.5
Sample B Female 209.5
Sample C Male 294.6
Sample D Male 175.8
Superior colliculi
nTPM: 356.5
Samples: 4

Max nTPM: 487.5
Min nTPM: 275.2
Sample A Female 387.6
Sample B Female 275.2
Sample C Male 487.5
Sample D Male 275.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1423.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 1423.8
Samples: 4

Max nTPM: 1445.1
Min nTPM: 1384.4
Sample A Male 1445.1
Sample B Male 1427.7
Sample C Female 1384.4
Sample D Female 1438.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 25.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 25.7
70528264 Antisense, RP_050623_02_C01, Mouse strain C57BL/6J (56 days, male) 25.7

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