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MRPL51
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.3 nTPM
HPA:155.3 nTPM
GTEx:167.3 nTPM
FANTOM5:95.0 Scaled Tags Per Million
Pig:26.3 nTPM
Mouse:15.8 nTPM
Allen mouse:3.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 151.8
2411 Female, age 72, unknown 159.4
1870 Female, age 42, unknown 157.8
2019 Male, age 18, unknown 154.3
1833 Male, age 53, unknown 152.6
1827 Male, age 72, unknown 152.5
2586 Male, age 75, left hemisphere 150.4
1830 Male, age 51, unknown 150.0
2828 Female, age 72, unknown 148.1
2666 Male, age 74, left hemisphere 147.3
2219 Male, age 76, both hemispheres 146.1
Dorsal raphe nucleus
nTPM: 153.8
1828 Male, age 53, unknown 156.7
2750 Male, age 76, both hemispheres 156.0
2298 Female, age 72, unknown 153.5
2047 Male, age 72, unknown 151.7
2016 Female, age 72, unknown 151.2
Inferior colliculus
nTPM: 150.9
1890 Male, age 53, unknown 152.3
2097 Female, age 72, unknown 151.3
1848 Female, age 42, unknown 150.0
2849 Male, age 72, unknown 149.9
Median raphe nucleus
nTPM: 152.6
2220 Male, age 76, midline 152.6
Pedunculopontine tegmental nucleus
nTPM: 154.7
2334 Male, age 80, both hemispheres 155.3
2338 Male, age 61, both hemispheres 154.8
1921 Female, age 85, both hemispheres 154.1
Periaquaductal grey, anterior
nTPM: 147.3
1947 Male, age 18, unknown 149.2
1795 Male, age 51, unknown 147.6
2502 Female, age 75, unknown 145.3
Periaquaductal grey, dorsal
nTPM: 149.3
1840 Male, age 53, unknown 150.9
2464 Female, age 72, unknown 149.1
2850 Male, age 76, both hemispheres 148.8
1831 Male, age 72, unknown 148.3
Periaquaductal grey, lateral
nTPM: 146.6
2053 Male, age 18, unknown 148.9
2140 Male, age 76, both hemispheres 146.4
2272 Male, age 74, both hemispheres 144.6
Pretectal area
nTPM: 150.6
1817 Female, age 42, unknown 156.0
2007 Male, age 72, unknown 154.4
1815 Male, age 53, unknown 153.1
1816 Male, age 51, unknown 152.1
2667 Female, age 75, unknown 151.8
2825 Male, age 18, unknown 150.7
1944 Female, age 72, unknown 150.1
2224 Female, age 72, unknown 148.3
2273 Male, age 74, both hemispheres 147.9
2407 Male, age 75, both hemispheres 146.2
2316 Male, age 76, right hemisphere 146.1
Red nucleus
nTPM: 154.5
1821 Female, age 72, unknown 166.8
1954 Female, age 42, unknown 156.3
1865 Male, age 51, unknown 155.8
2503 Female, age 72, unknown 155.3
2725 Female, age 75, unknown 154.9
1904 Male, age 53, unknown 153.9
2227 Male, age 72, unknown 153.9
2588 Male, age 74, left hemisphere 153.8
2823 Male, age 76, right hemisphere 152.9
2769 Male, age 72, unknown 151.9
2785 Male, age 18, unknown 150.4
2584 Male, age 75, left hemisphere 148.4
Substantia nigra
nTPM: 155.3
1916 Female, age 42, unknown 160.7
1851 Male, age 51, unknown 159.3
2241 Male, age 72, unknown 158.7
2409 Female, age 72, unknown 158.4
1889 Female, age 72, unknown 155.7
2665 Male, age 74, both hemispheres 154.7
2699 Male, age 18, unknown 152.8
1941 Male, age 53, unknown 152.3
2590 Female, age 75, unknown 151.4
2583 Male, age 75, right hemisphere 149.3
Superior colliculus
nTPM: 151.4
1895 Male, age 76, right hemisphere 156.2
2668 Female, age 75, unknown 155.5
2587 Male, age 74, left hemisphere 154.3
1913 Female, age 42, unknown 152.1
1839 Male, age 51, unknown 150.2
1995 Male, age 72, unknown 150.1
2087 Female, age 72, unknown 150.1
2261 Male, age 18, unknown 149.4
1796 Male, age 53, unknown 149.0
2664 Male, age 75, both hemispheres 147.1
Ventral tegmental area
nTPM: 152.7
2410 Female, age 72, unknown 156.7
1915 Female, age 42, unknown 156.6
2223 Female, age 72, unknown 154.8
2218 Male, age 76, both hemispheres 151.4
1942 Male, age 51, unknown 148.5
2021 Male, age 53, unknown 148.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 167.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 167.3
Samples: 139

Max nTPM: 376.2
Min nTPM: 100.4
Std nTPM: 40.8
Median nTPM: 158.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 376.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 318.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 305.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 268.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 251.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 246.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 244.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 243.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 241.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 238.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 233.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 218.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 213.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 213.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 213.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 210.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 206.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 206.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 206.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 200.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 198.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 198.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 197.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 197.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 197.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 195.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 191.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 189.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 188.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 187.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 187.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 184.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 184.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 183.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 181.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 179.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 178.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 178.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 178.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 178.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 177.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 177.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 177.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 177.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 176.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 175.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 175.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 175.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 173.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 172.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 171.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 170.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 169.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 168.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 168.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 168.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 166.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 165.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 164.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 164.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 163.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 162.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 162.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 161.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 161.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 161.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 159.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 159.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 158.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 158.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 158.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 156.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 156.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 156.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 155.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 155.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 154.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 153.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 153.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 153.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 153.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 153.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 153.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 151.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 151.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 151.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 150.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 150.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 148.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 148.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 148.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 148.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 148.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 147.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 146.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 146.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 146.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 146.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 146.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 145.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 145.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 144.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 143.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 141.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 141.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 141.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 140.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 140.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 140.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 140.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 139.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 138.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 138.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 135.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 135.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 135.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 135.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 132.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 132.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 132.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 131.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 127.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 126.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 126.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 126.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 125.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 123.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 122.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 121.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 120.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 119.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 119.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 118.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 117.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 115.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 111.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 111.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 100.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 95.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 95.0
FF:10158-103A5 76 years, female 95.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 26.3
Pig sample Sample description nTPM
Midbrain
nTPM: 23.8
Samples: 4

Max nTPM: 27.2
Min nTPM: 18.7
Sample A Female 24.5
Sample B Female 18.7
Sample C Male 27.2
Sample D Male 24.9
Periaqueductal gray
nTPM: 19.8
Samples: 3

Max nTPM: 21.3
Min nTPM: 18.4
Sample B Female 19.6
Sample C Male 21.3
Sample D Male 18.4
Substantia nigra
nTPM: 22.2
Samples: 4

Max nTPM: 30.4
Min nTPM: 16.6
Sample A Female 30.4
Sample B Female 16.6
Sample C Male 24.8
Sample D Male 17.1
Superior colliculi
nTPM: 26.3
Samples: 4

Max nTPM: 33.5
Min nTPM: 16.3
Sample A Female 33.5
Sample B Female 16.3
Sample C Male 31.9
Sample D Male 23.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 15.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 15.8
Samples: 4

Max nTPM: 16.2
Min nTPM: 15.1
Sample A Male 15.1
Sample B Male 15.6
Sample C Female 16.2
Sample D Female 16.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.5
68410452 Antisense, RP_041214_01_H10, Mouse strain C57BL/6J (56 days, male) 3.5

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