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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:70.6 nTPM
HPA:70.6 nTPM
GTEx:79.8 nTPM
FANTOM5:139.9 Scaled Tags Per Million
Pig:86.1 nTPM
Mouse:31.1 nTPM
Allen mouse:11.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 70.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.7
2586 Male, age 75, left hemisphere 105.2
2666 Male, age 74, left hemisphere 81.7
2828 Female, age 72, unknown 80.2
1827 Male, age 72, unknown 64.5
2219 Male, age 76, both hemispheres 64.0
1833 Male, age 53, unknown 60.0
1870 Female, age 42, unknown 52.8
1830 Male, age 51, unknown 51.7
2019 Male, age 18, unknown 34.2
2411 Female, age 72, unknown 32.5
Dorsal raphe nucleus
nTPM: 39.7
1828 Male, age 53, unknown 53.0
2016 Female, age 72, unknown 43.5
2047 Male, age 72, unknown 42.1
2750 Male, age 76, both hemispheres 31.4
2298 Female, age 72, unknown 28.5
Inferior colliculus
nTPM: 65.5
2849 Male, age 72, unknown 106.5
1848 Female, age 42, unknown 63.2
1890 Male, age 53, unknown 53.9
2097 Female, age 72, unknown 38.3
Median raphe nucleus
nTPM: 54.2
2220 Male, age 76, midline 54.2
Pedunculopontine tegmental nucleus
nTPM: 46.5
2334 Male, age 80, both hemispheres 51.4
2338 Male, age 61, both hemispheres 48.6
1921 Female, age 85, both hemispheres 39.5
Periaquaductal grey, anterior
nTPM: 65.4
1947 Male, age 18, unknown 70.1
1795 Male, age 51, unknown 66.1
2502 Female, age 75, unknown 59.8
Periaquaductal grey, dorsal
nTPM: 70.6
2850 Male, age 76, both hemispheres 106.4
1840 Male, age 53, unknown 63.8
1831 Male, age 72, unknown 57.9
2464 Female, age 72, unknown 54.4
Periaquaductal grey, lateral
nTPM: 61.8
2140 Male, age 76, both hemispheres 83.2
2053 Male, age 18, unknown 56.1
2272 Male, age 74, both hemispheres 46.1
Pretectal area
nTPM: 57.3
2407 Male, age 75, both hemispheres 75.3
2825 Male, age 18, unknown 73.3
1816 Male, age 51, unknown 64.8
1817 Female, age 42, unknown 63.0
1815 Male, age 53, unknown 58.5
2667 Female, age 75, unknown 58.1
1944 Female, age 72, unknown 53.1
2007 Male, age 72, unknown 49.4
2316 Male, age 76, right hemisphere 48.5
2224 Female, age 72, unknown 44.8
2273 Male, age 74, both hemispheres 41.3
Red nucleus
nTPM: 51.6
2584 Male, age 75, left hemisphere 62.8
2725 Female, age 75, unknown 60.8
2588 Male, age 74, left hemisphere 59.6
2769 Male, age 72, unknown 58.4
2227 Male, age 72, unknown 57.1
2823 Male, age 76, right hemisphere 54.3
2503 Female, age 72, unknown 48.5
1954 Female, age 42, unknown 48.4
1865 Male, age 51, unknown 45.9
2785 Male, age 18, unknown 43.4
1904 Male, age 53, unknown 41.2
1821 Female, age 72, unknown 38.6
Substantia nigra
nTPM: 45.6
2699 Male, age 18, unknown 71.2
2665 Male, age 74, both hemispheres 62.5
1916 Female, age 42, unknown 51.0
2583 Male, age 75, right hemisphere 50.9
1941 Male, age 53, unknown 44.9
1889 Female, age 72, unknown 44.1
1851 Male, age 51, unknown 43.5
2590 Female, age 75, unknown 40.0
2409 Female, age 72, unknown 23.8
2241 Male, age 72, unknown 23.7
Superior colliculus
nTPM: 60.5
2664 Male, age 75, both hemispheres 109.4
1796 Male, age 53, unknown 64.4
1839 Male, age 51, unknown 64.2
2668 Female, age 75, unknown 58.4
2261 Male, age 18, unknown 55.5
2587 Male, age 74, left hemisphere 51.5
1913 Female, age 42, unknown 51.4
2087 Female, age 72, unknown 50.7
1995 Male, age 72, unknown 50.1
1895 Male, age 76, right hemisphere 49.6
Ventral tegmental area
nTPM: 44.8
2223 Female, age 72, unknown 49.8
2218 Male, age 76, both hemispheres 47.6
1942 Male, age 51, unknown 46.5
2021 Male, age 53, unknown 46.0
1915 Female, age 42, unknown 45.6
2410 Female, age 72, unknown 33.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 79.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 79.8
Samples: 139

Max nTPM: 160.9
Min nTPM: 49.6
Std nTPM: 17.2
Median nTPM: 76.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 160.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 133.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 127.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 123.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 116.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 109.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 109.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 109.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 107.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 101.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 100.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 100.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 100.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 98.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 98.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 98.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 97.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 96.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 95.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 94.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 93.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 93.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 93.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 92.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 92.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 92.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 91.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 90.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 89.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 89.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 89.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 88.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 88.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 88.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 88.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 87.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 87.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 87.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 86.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 86.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 86.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 86.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 86.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 85.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 85.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 84.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 84.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 84.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 83.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 83.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 83.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 82.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 82.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 82.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 81.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 81.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 80.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 80.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 79.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 79.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 78.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 78.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 77.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 77.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 77.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 77.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 77.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 76.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 76.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 76.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 76.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 76.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 75.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 75.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 75.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 74.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 74.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 74.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 74.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 74.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 74.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 73.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 73.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 72.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 72.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 72.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 72.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 72.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 71.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 71.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 70.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 70.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 70.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 70.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 69.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 69.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 69.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 68.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 68.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 67.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 67.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 67.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 67.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 67.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 66.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 66.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 65.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 65.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 65.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 65.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 64.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 64.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 64.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 64.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 63.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 63.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 63.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 61.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 61.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 61.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 58.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 58.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 57.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 57.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 56.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 56.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 56.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 55.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 55.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 53.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 139.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.9
FF:10158-103A5 76 years, female 139.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 86.1
Pig sample Sample description nTPM
Midbrain
nTPM: 81.7
Samples: 4

Max nTPM: 106.4
Min nTPM: 62.6
Sample A Female 65.0
Sample B Female 62.6
Sample C Male 106.4
Sample D Male 92.6
Periaqueductal gray
nTPM: 68.4
Samples: 3

Max nTPM: 75.8
Min nTPM: 64.1
Sample B Female 64.1
Sample C Male 75.8
Sample D Male 65.3
Substantia nigra
nTPM: 63.9
Samples: 4

Max nTPM: 76.2
Min nTPM: 56.1
Sample A Female 63.9
Sample B Female 56.1
Sample C Male 76.2
Sample D Male 59.5
Superior colliculi
nTPM: 86.1
Samples: 4

Max nTPM: 108.6
Min nTPM: 55.6
Sample A Female 87.4
Sample B Female 55.6
Sample C Male 92.9
Sample D Male 108.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 31.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 31.1
Samples: 4

Max nTPM: 34.9
Min nTPM: 28.2
Sample A Male 34.9
Sample B Male 28.2
Sample C Female 30.1
Sample D Female 31.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.1
68911027 Antisense, RP_050203_02_G07, Mouse strain C57BL/6J (56 days, male) 11.1

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