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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:349.7 nTPM
HPA:349.7 nTPM
GTEx:391.7 nTPM
FANTOM5:147.5 Scaled Tags Per Million
Pig:244.5 nTPM
Mouse:509.7 nTPM
Allen mouse:6.7 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 349.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 334.3
2019 Male, age 18, unknown 355.2
2411 Female, age 72, unknown 351.9
1870 Female, age 42, unknown 341.0
1827 Male, age 72, unknown 339.9
2219 Male, age 76, both hemispheres 330.8
1833 Male, age 53, unknown 327.6
2666 Male, age 74, left hemisphere 327.1
1830 Male, age 51, unknown 325.3
2828 Female, age 72, unknown 324.2
2586 Male, age 75, left hemisphere 319.6
Dorsal raphe nucleus
nTPM: 339.0
2298 Female, age 72, unknown 359.6
1828 Male, age 53, unknown 341.0
2047 Male, age 72, unknown 335.9
2750 Male, age 76, both hemispheres 333.2
2016 Female, age 72, unknown 325.1
Inferior colliculus
nTPM: 346.2
2097 Female, age 72, unknown 378.3
1890 Male, age 53, unknown 351.6
1848 Female, age 42, unknown 336.1
2849 Male, age 72, unknown 319.0
Median raphe nucleus
nTPM: 327.4
2220 Male, age 76, midline 327.4
Pedunculopontine tegmental nucleus
nTPM: 346.3
1921 Female, age 85, both hemispheres 352.7
2338 Male, age 61, both hemispheres 345.6
2334 Male, age 80, both hemispheres 340.7
Periaquaductal grey, anterior
nTPM: 339.7
1947 Male, age 18, unknown 345.8
2502 Female, age 75, unknown 340.4
1795 Male, age 51, unknown 333.0
Periaquaductal grey, dorsal
nTPM: 326.3
2464 Female, age 72, unknown 331.0
1840 Male, age 53, unknown 328.6
1831 Male, age 72, unknown 326.3
2850 Male, age 76, both hemispheres 319.1
Periaquaductal grey, lateral
nTPM: 328.3
2272 Male, age 74, both hemispheres 339.6
2053 Male, age 18, unknown 330.7
2140 Male, age 76, both hemispheres 314.6
Pretectal area
nTPM: 344.4
2007 Male, age 72, unknown 368.4
1816 Male, age 51, unknown 365.9
1817 Female, age 42, unknown 359.8
1944 Female, age 72, unknown 356.9
1815 Male, age 53, unknown 350.6
2224 Female, age 72, unknown 345.2
2667 Female, age 75, unknown 336.5
2273 Male, age 74, both hemispheres 334.7
2316 Male, age 76, right hemisphere 327.5
2825 Male, age 18, unknown 324.0
2407 Male, age 75, both hemispheres 318.8
Red nucleus
nTPM: 349.7
1821 Female, age 72, unknown 391.9
2725 Female, age 75, unknown 366.3
2503 Female, age 72, unknown 358.5
2785 Male, age 18, unknown 349.7
1865 Male, age 51, unknown 347.3
1904 Male, age 53, unknown 346.6
2227 Male, age 72, unknown 346.4
2769 Male, age 72, unknown 342.9
2588 Male, age 74, left hemisphere 340.1
2823 Male, age 76, right hemisphere 339.9
1954 Female, age 42, unknown 339.6
2584 Male, age 75, left hemisphere 327.1
Substantia nigra
nTPM: 346.1
1889 Female, age 72, unknown 365.4
1916 Female, age 42, unknown 361.3
1851 Male, age 51, unknown 361.2
2241 Male, age 72, unknown 359.3
1941 Male, age 53, unknown 346.0
2409 Female, age 72, unknown 345.1
2665 Male, age 74, both hemispheres 334.9
2590 Female, age 75, unknown 330.8
2699 Male, age 18, unknown 330.0
2583 Male, age 75, right hemisphere 327.4
Superior colliculus
nTPM: 334.0
2587 Male, age 74, left hemisphere 347.1
1895 Male, age 76, right hemisphere 340.0
2087 Female, age 72, unknown 338.5
2668 Female, age 75, unknown 337.8
1796 Male, age 53, unknown 336.9
2261 Male, age 18, unknown 336.2
1913 Female, age 42, unknown 335.2
1995 Male, age 72, unknown 329.6
1839 Male, age 51, unknown 326.8
2664 Male, age 75, both hemispheres 311.8
Ventral tegmental area
nTPM: 344.3
2410 Female, age 72, unknown 360.8
1915 Female, age 42, unknown 352.6
2223 Female, age 72, unknown 351.7
2218 Male, age 76, both hemispheres 340.2
1942 Male, age 51, unknown 334.9
2021 Male, age 53, unknown 325.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 391.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 391.7
Samples: 139

Max nTPM: 1078.0
Min nTPM: 210.6
Std nTPM: 129.8
Median nTPM: 369.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1078.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 924.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 791.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 740.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 680.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 636.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 611.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 611.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 594.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 584.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 574.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 570.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 569.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 562.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 560.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 558.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 553.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 507.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 497.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 496.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 493.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 473.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 472.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 460.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 458.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 455.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 453.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 450.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 447.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 444.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 443.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 438.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 436.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 436.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 435.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 435.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 431.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 430.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 429.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 427.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 424.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 421.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 420.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 419.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 414.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 413.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 413.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 411.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 408.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 405.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 403.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 403.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 402.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 401.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 400.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 400.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 395.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 392.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 392.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 389.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 388.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 384.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 383.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 381.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 374.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 372.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 370.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 369.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 369.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 369.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 368.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 367.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 366.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 363.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 362.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 361.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 359.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 354.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 353.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 349.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 346.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 346.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 343.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 337.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 335.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 334.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 334.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 334.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 333.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 331.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 327.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 326.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 325.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 325.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 324.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 323.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 323.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 322.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 319.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 318.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 318.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 315.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 314.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 314.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 313.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 313.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 309.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 309.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 307.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 305.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 304.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 293.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 290.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 288.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 287.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 287.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 282.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 279.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 278.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 273.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 265.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 263.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 262.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 261.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 259.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 259.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 256.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 255.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 251.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 250.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 244.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 241.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 241.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 239.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 233.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 230.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 228.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 225.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 210.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 147.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 147.5
FF:10158-103A5 76 years, female 147.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 244.5
Pig sample Sample description nTPM
Midbrain
nTPM: 202.6
Samples: 4

Max nTPM: 254.0
Min nTPM: 167.3
Sample A Female 198.4
Sample B Female 167.3
Sample C Male 254.0
Sample D Male 190.6
Periaqueductal gray
nTPM: 117.5
Samples: 3

Max nTPM: 130.4
Min nTPM: 102.3
Sample B Female 130.4
Sample C Male 119.8
Sample D Male 102.3
Substantia nigra
nTPM: 188.7
Samples: 4

Max nTPM: 286.1
Min nTPM: 128.8
Sample A Female 286.1
Sample B Female 163.0
Sample C Male 176.7
Sample D Male 128.8
Superior colliculi
nTPM: 244.5
Samples: 4

Max nTPM: 322.0
Min nTPM: 175.7
Sample A Female 255.3
Sample B Female 224.8
Sample C Male 322.0
Sample D Male 175.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 509.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 509.7
Samples: 4

Max nTPM: 531.6
Min nTPM: 496.7
Sample A Male 531.6
Sample B Male 496.7
Sample C Female 500.4
Sample D Female 509.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.7
68301443 Antisense, RP_041130_01_C06, Mouse strain C57BL/6J (56 days, male) 6.7

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