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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:237.7 nTPM
HPA:237.7 nTPM
GTEx:299.3 nTPM
FANTOM5:580.3 Scaled Tags Per Million
Pig:56.8 nTPM
Mouse:89.8 nTPM
Allen mouse:13.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 237.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 216.4
2828 Female, age 72, unknown 236.8
1870 Female, age 42, unknown 233.8
1830 Male, age 51, unknown 229.5
2586 Male, age 75, left hemisphere 224.7
2666 Male, age 74, left hemisphere 223.0
1833 Male, age 53, unknown 221.9
2411 Female, age 72, unknown 212.6
2019 Male, age 18, unknown 206.7
1827 Male, age 72, unknown 193.1
2219 Male, age 76, both hemispheres 181.9
Dorsal raphe nucleus
nTPM: 205.2
2016 Female, age 72, unknown 232.8
1828 Male, age 53, unknown 215.4
2750 Male, age 76, both hemispheres 206.8
2047 Male, age 72, unknown 200.1
2298 Female, age 72, unknown 171.0
Inferior colliculus
nTPM: 192.9
1848 Female, age 42, unknown 202.8
2849 Male, age 72, unknown 197.2
1890 Male, age 53, unknown 196.9
2097 Female, age 72, unknown 174.8
Median raphe nucleus
nTPM: 194.9
2220 Male, age 76, midline 194.9
Pedunculopontine tegmental nucleus
nTPM: 198.4
2334 Male, age 80, both hemispheres 216.2
2338 Male, age 61, both hemispheres 197.9
1921 Female, age 85, both hemispheres 181.0
Periaquaductal grey, anterior
nTPM: 185.3
2502 Female, age 75, unknown 188.6
1947 Male, age 18, unknown 184.5
1795 Male, age 51, unknown 182.8
Periaquaductal grey, dorsal
nTPM: 194.5
2464 Female, age 72, unknown 199.7
2850 Male, age 76, both hemispheres 199.5
1831 Male, age 72, unknown 198.7
1840 Male, age 53, unknown 180.0
Periaquaductal grey, lateral
nTPM: 192.3
2053 Male, age 18, unknown 207.0
2140 Male, age 76, both hemispheres 195.4
2272 Male, age 74, both hemispheres 174.6
Pretectal area
nTPM: 186.7
1815 Male, age 53, unknown 208.3
2407 Male, age 75, both hemispheres 206.2
2316 Male, age 76, right hemisphere 206.1
2825 Male, age 18, unknown 199.2
1817 Female, age 42, unknown 192.8
2224 Female, age 72, unknown 181.0
2273 Male, age 74, both hemispheres 176.0
1944 Female, age 72, unknown 174.7
2007 Male, age 72, unknown 174.4
2667 Female, age 75, unknown 170.6
1816 Male, age 51, unknown 164.1
Red nucleus
nTPM: 237.7
1865 Male, age 51, unknown 258.1
1904 Male, age 53, unknown 250.5
1954 Female, age 42, unknown 250.4
2503 Female, age 72, unknown 247.5
2588 Male, age 74, left hemisphere 243.6
2823 Male, age 76, right hemisphere 241.2
2227 Male, age 72, unknown 238.8
2769 Male, age 72, unknown 237.5
1821 Female, age 72, unknown 232.0
2725 Female, age 75, unknown 223.6
2785 Male, age 18, unknown 219.4
2584 Male, age 75, left hemisphere 209.9
Substantia nigra
nTPM: 205.1
2699 Male, age 18, unknown 229.8
2590 Female, age 75, unknown 218.1
2583 Male, age 75, right hemisphere 215.5
2409 Female, age 72, unknown 215.4
1851 Male, age 51, unknown 211.7
2665 Male, age 74, both hemispheres 209.5
1889 Female, age 72, unknown 193.7
2241 Male, age 72, unknown 193.3
1941 Male, age 53, unknown 184.0
1916 Female, age 42, unknown 179.8
Superior colliculus
nTPM: 208.2
1995 Male, age 72, unknown 252.5
1913 Female, age 42, unknown 250.4
2668 Female, age 75, unknown 219.7
2587 Male, age 74, left hemisphere 209.6
1839 Male, age 51, unknown 203.4
2664 Male, age 75, both hemispheres 198.7
1895 Male, age 76, right hemisphere 195.1
2087 Female, age 72, unknown 189.7
1796 Male, age 53, unknown 185.2
2261 Male, age 18, unknown 177.4
Ventral tegmental area
nTPM: 204.2
2223 Female, age 72, unknown 209.8
2410 Female, age 72, unknown 209.5
2021 Male, age 53, unknown 207.6
1915 Female, age 42, unknown 204.3
1942 Male, age 51, unknown 204.3
2218 Male, age 76, both hemispheres 189.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 299.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 299.3
Samples: 139

Max nTPM: 749.1
Min nTPM: 70.0
Std nTPM: 142.8
Median nTPM: 255.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 749.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 731.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 697.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 640.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 632.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 623.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 603.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 602.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 577.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 543.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 531.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 521.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 486.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 472.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 466.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 462.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 462.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 457.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 448.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 448.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 447.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 444.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 443.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 443.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 442.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 442.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 441.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 440.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 438.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 407.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 400.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 398.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 397.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 397.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 393.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 393.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 388.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 385.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 367.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 367.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 366.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 358.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 356.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 354.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 349.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 346.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 345.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 341.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 341.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 339.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 323.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 319.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 318.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 314.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 313.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 311.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 298.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 294.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 291.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 287.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 286.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 279.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 273.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 266.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 265.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 265.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 262.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 262.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 258.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 255.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 254.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 253.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 252.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 248.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 247.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 246.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 246.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 244.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 244.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 243.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 243.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 234.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 229.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 227.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 225.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 221.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 221.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 218.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 218.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 217.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 214.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 213.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 209.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 207.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 207.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 205.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 204.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 201.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 200.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 200.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 199.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 197.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 196.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 193.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 190.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 186.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 185.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 184.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 183.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 180.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 179.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 176.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 175.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 175.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 170.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 170.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 169.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 167.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 165.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 160.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 159.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 159.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 155.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 147.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 146.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 144.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 143.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 141.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 141.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 139.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 135.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 133.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 133.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 121.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 112.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 110.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 110.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 91.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 70.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 580.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 580.3
FF:10158-103A5 76 years, female 580.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 56.8
Pig sample Sample description nTPM
Midbrain
nTPM: 50.8
Samples: 4

Max nTPM: 71.8
Min nTPM: 31.4
Sample A Female 71.8
Sample B Female 42.4
Sample C Male 57.4
Sample D Male 31.4
Periaqueductal gray
nTPM: 37.3
Samples: 3

Max nTPM: 43.4
Min nTPM: 25.8
Sample B Female 42.7
Sample C Male 43.4
Sample D Male 25.8
Substantia nigra
nTPM: 51.2
Samples: 4

Max nTPM: 60.4
Min nTPM: 41.1
Sample A Female 60.4
Sample B Female 41.1
Sample C Male 46.8
Sample D Male 56.5
Superior colliculi
nTPM: 56.8
Samples: 4

Max nTPM: 87.8
Min nTPM: 40.5
Sample A Female 56.6
Sample B Female 42.3
Sample C Male 87.8
Sample D Male 40.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 89.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 89.8
Samples: 4

Max nTPM: 91.1
Min nTPM: 87.1
Sample A Male 87.1
Sample B Male 90.1
Sample C Female 91.1
Sample D Female 90.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.3
79556599 Antisense, RP_071018_02_A06, Mouse strain C57BL/6J (56 days, male) 13.3
79360312 Antisense, RP_071018_02_A06, Mouse strain C57BL/6J (56 days, male) 7.2

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