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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 75.5
Min nTPM: 9.3
Std nTPM: 12.4
Median nTPM:
452_1
88 years, female
75.5
351_1
91 years, male
63.0
163_1
78 years, male
57.9
354_1
81 years, female
57.7
218_1
71 years, female
57.0
173_1
67 years, male
56.4
353_1
82 years, female
55.7
295_1
61 years, female
54.8
356_1
87 years, female
54.2
506_1
65 years, male
52.5
237_1
82 years, male
49.5
320_1
89 years, female
49.5
264_1
73 years, female
49.4
384_1
83 years, male
49.3
177_1
74 years, male
49.0
349_1
83 years, male
48.7
376_1
75 years, female
48.6
394_1
75 years, female
47.8
319_1
81 years, male
47.4
375_1
74 years, female
47.0
406_1
79 years, male
46.3
322_1
76 years, male
45.6
379_1
60 years, male
45.5
189_1
76 years, male
45.1
389_1
86 years, female
44.1
317_1
60 years, male
43.5
293_1
68 years, female
43.1
347_1
72 years, male
43.1
503_1
68 years, male
42.9
41_1
94 years, female
42.8
314_1
67 years, male
42.8
377_1
82 years, female
42.8
243_1
75 years, male
42.4
480_1
63 years, male
42.4
286_1
68 years, female
41.1
335_1
73 years, female
40.6
404_1
82 years, female
40.2
318_1
68 years, male
39.9
172_1
72 years, female
39.7
137_1
83 years, male
39.4
99_1
64 years, male
39.2
350_1
84 years, female
39.1
321_1
62 years, female
38.7
251_1
78 years, male
37.6
316_1
62 years, male
37.6
348_1
84 years, male
37.4
526_1
61 years, male
37.4
292_1
71 years, male
37.1
447_1
81 years, male
37.1
425_1
59 years, female
36.5
405_1
91 years, male
36.4
254_1
77 years, female
35.4
291_1
76 years, male
35.1
315_1
62 years, female
35.0
355_1
70 years, female
34.9
352_1
62 years, male
34.8
288_1
66 years, female
34.0
145_1
84 years, male
33.7
308_1
70 years, female
33.7
386_1
76 years, male
33.6
517_1
88 years, male
33.0
17_1
71 years, male
32.7
313_1
79 years, female
32.5
109_1
81 years, female
32.4
266_1
85 years, male
32.3
4_1
88 years, female
32.2
518_1
75 years, female
31.6
265_1
87 years, male
31.5
307_1
66 years, female
31.4
396_1
62 years, male
31.0
35_1
74 years, female
30.7
311_1
78 years, male
30.3
468_1
89 years, male
28.8
246_1
77 years, male
28.6
324_1
76 years, male
28.5
499_1
55 years, female
28.1
6_1
73 years, female
28.0
42_1
85 years, male
28.0
501_1
88 years, male
27.9
18_1
88 years, male
27.1
229_1
69 years, female
27.1
120_1
70 years, female
26.7
9_1
66 years, female
24.7
115_1
83 years, male
24.2
117_1
61 years, male
24.0
153_1
70 years, female
23.4
415_1
77 years, female
23.3
217_1
76 years, male
23.2
2_1
77 years, female
23.1
126_1
63 years, male
22.6
495_1
57 years, female
22.5
142_1
61 years, female
22.2
414_1
84 years, female
21.7
139_1
64 years, female
19.7
119_1
70 years, female
19.2
162_1
79 years, female
18.7
81_1
67 years, male
18.4
32_1
67 years, male
16.8
466_1
57 years, female
15.6
43_1
64 years, female
15.1
89_1
63 years, male
13.4
491_1
89 years, female
10.4
149_1
88 years, male
10.0
413_1
59 years, female
9.7
490_1
67 years, female
9.3
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
