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  • EFHD1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:258.7 nTPM
HPA:258.7 nTPM
GTEx:274.2 nTPM
FANTOM5:848.6 Scaled Tags Per Million
Pig:70.7 nTPM
Mouse:48.6 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 258.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 228.7
1870 Female, age 42, unknown 265.3
1830 Male, age 51, unknown 258.9
1833 Male, age 53, unknown 253.2
2828 Female, age 72, unknown 245.5
2411 Female, age 72, unknown 244.0
2019 Male, age 18, unknown 231.1
2666 Male, age 74, left hemisphere 210.8
1827 Male, age 72, unknown 199.8
2586 Male, age 75, left hemisphere 191.3
2219 Male, age 76, both hemispheres 186.8
Dorsal raphe nucleus
nTPM: 197.9
2750 Male, age 76, both hemispheres 256.8
2016 Female, age 72, unknown 209.7
1828 Male, age 53, unknown 194.4
2298 Female, age 72, unknown 166.5
2047 Male, age 72, unknown 162.0
Inferior colliculus
nTPM: 186.8
2849 Male, age 72, unknown 200.3
1848 Female, age 42, unknown 189.6
1890 Male, age 53, unknown 188.8
2097 Female, age 72, unknown 168.5
Median raphe nucleus
nTPM: 181.0
2220 Male, age 76, midline 181.0
Pedunculopontine tegmental nucleus
nTPM: 212.9
2334 Male, age 80, both hemispheres 230.2
2338 Male, age 61, both hemispheres 216.0
1921 Female, age 85, both hemispheres 192.5
Periaquaductal grey, anterior
nTPM: 190.8
2502 Female, age 75, unknown 209.6
1947 Male, age 18, unknown 188.6
1795 Male, age 51, unknown 174.2
Periaquaductal grey, dorsal
nTPM: 185.3
2464 Female, age 72, unknown 202.4
2850 Male, age 76, both hemispheres 200.1
1831 Male, age 72, unknown 179.5
1840 Male, age 53, unknown 159.3
Periaquaductal grey, lateral
nTPM: 195.0
2140 Male, age 76, both hemispheres 201.6
2053 Male, age 18, unknown 197.1
2272 Male, age 74, both hemispheres 186.2
Pretectal area
nTPM: 194.9
2667 Female, age 75, unknown 232.2
2316 Male, age 76, right hemisphere 226.1
1815 Male, age 53, unknown 214.1
2825 Male, age 18, unknown 197.3
1817 Female, age 42, unknown 192.9
2407 Male, age 75, both hemispheres 192.0
2273 Male, age 74, both hemispheres 190.7
2007 Male, age 72, unknown 182.3
2224 Female, age 72, unknown 180.3
1944 Female, age 72, unknown 173.4
1816 Male, age 51, unknown 162.2
Red nucleus
nTPM: 258.7
1865 Male, age 51, unknown 293.6
2769 Male, age 72, unknown 287.2
2227 Male, age 72, unknown 285.7
2823 Male, age 76, right hemisphere 274.3
1904 Male, age 53, unknown 271.7
1821 Female, age 72, unknown 264.5
2503 Female, age 72, unknown 263.0
2785 Male, age 18, unknown 258.6
1954 Female, age 42, unknown 252.7
2588 Male, age 74, left hemisphere 227.1
2584 Male, age 75, left hemisphere 216.3
2725 Female, age 75, unknown 209.5
Substantia nigra
nTPM: 202.0
2699 Male, age 18, unknown 237.2
1851 Male, age 51, unknown 220.4
2409 Female, age 72, unknown 220.1
2583 Male, age 75, right hemisphere 207.5
2590 Female, age 75, unknown 199.6
1889 Female, age 72, unknown 198.1
1941 Male, age 53, unknown 194.2
2241 Male, age 72, unknown 184.2
1916 Female, age 42, unknown 182.0
2665 Male, age 74, both hemispheres 176.3
Superior colliculus
nTPM: 213.9
1913 Female, age 42, unknown 285.5
1995 Male, age 72, unknown 273.8
1895 Male, age 76, right hemisphere 224.8
1839 Male, age 51, unknown 220.4
2587 Male, age 74, left hemisphere 214.9
1796 Male, age 53, unknown 201.4
2668 Female, age 75, unknown 188.4
2087 Female, age 72, unknown 180.2
2664 Male, age 75, both hemispheres 179.2
2261 Male, age 18, unknown 170.2
Ventral tegmental area
nTPM: 212.9
2223 Female, age 72, unknown 241.0
2410 Female, age 72, unknown 235.3
2218 Male, age 76, both hemispheres 202.6
2021 Male, age 53, unknown 202.4
1915 Female, age 42, unknown 198.9
1942 Male, age 51, unknown 197.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 274.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 274.2
Samples: 139

Max nTPM: 768.5
Min nTPM: 75.8
Std nTPM: 120.5
Median nTPM: 246.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 768.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 683.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 651.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 573.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 518.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 515.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 512.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 506.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 502.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 497.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 492.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 469.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 466.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 457.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 456.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 447.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 436.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 406.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 396.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 391.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 385.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 372.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 368.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 367.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 360.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 360.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 350.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 347.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 340.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 340.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 339.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 334.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 333.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 325.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 321.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 319.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 315.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 315.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 313.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 313.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 308.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 305.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 305.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 303.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 303.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 297.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 292.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 289.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 288.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 287.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 283.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 283.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 282.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 280.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 280.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 275.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 273.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 272.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 271.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 268.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 267.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 266.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 265.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 262.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 260.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 257.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 252.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 249.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 248.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 246.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 245.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 241.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 241.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 240.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 235.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 234.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 234.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 233.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 232.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 231.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 227.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 227.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 226.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 226.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 225.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 222.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 219.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 219.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 217.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 215.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 214.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 213.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 208.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 208.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 208.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 201.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 198.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 198.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 196.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 194.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 190.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 189.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 189.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 188.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 188.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 187.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 184.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 183.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 182.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 182.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 178.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 178.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 178.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 176.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 175.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 175.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 172.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 171.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 170.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 169.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 167.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 158.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 158.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 151.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 150.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 147.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 145.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 141.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 139.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 138.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 132.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 132.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 131.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 129.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 119.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 103.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 90.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 75.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 848.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 848.6
FF:10158-103A5 76 years, female 848.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 70.7
Pig sample Sample description nTPM
Midbrain
nTPM: 70.7
Samples: 4

Max nTPM: 119.2
Min nTPM: 27.1
Sample A Female 119.2
Sample B Female 106.2
Sample C Male 30.2
Sample D Male 27.1
Periaqueductal gray
nTPM: 51.8
Samples: 3

Max nTPM: 83.7
Min nTPM: 33.7
Sample B Female 83.7
Sample C Male 33.7
Sample D Male 38.0
Substantia nigra
nTPM: 67.8
Samples: 4

Max nTPM: 86.1
Min nTPM: 45.1
Sample A Female 55.8
Sample B Female 84.1
Sample C Male 45.1
Sample D Male 86.1
Superior colliculi
nTPM: 55.1
Samples: 4

Max nTPM: 60.0
Min nTPM: 48.1
Sample A Female 60.0
Sample B Female 56.5
Sample C Male 48.1
Sample D Male 55.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 48.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 48.6
Samples: 4

Max nTPM: 50.7
Min nTPM: 45.2
Sample A Male 50.7
Sample B Male 45.2
Sample C Female 48.8
Sample D Female 49.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
638709 Antisense, RP_040831_02_C07, Mouse strain C57BL/6J (56 days, male) 0.0

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