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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA031844
Moderate cytoplasmic and membranous positivity was observed in pancreatic islets, superficial layers of squamous epithelium, renal tubules, seminiferous duct cells, muscle, neuronal cells and subsets of lymphoid cells. Trophoblastic cells, large intestine, purkinje cells and subsets of bone marrow cells were strongly stained. Most normal tissues were weakly stained or negative.
HPA031845
Normal tissues showed weak to moderate cytoplasmic staining combined with additional nuclear positivity in several tissues. Membranous staining was observed in bronchus, epididymis and salivary gland. Epididymis and cells in seminiferus tubules were strongly stained. Glial cells and hepatocytes were negative.
HPA031846
Normal tissues generally showed moderate cytoplasmic staining. Renal tubules, cells in seminiferous ducts, hematopoietic cells and reaction center cells displayed strong cytoplasmic positivity. The liver, renal glomeruli and glial cells were weakly stained or negative.