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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA005922
Normal tissues displayed cytoplasmic staining, often accompanied with nuclear or nucleolar positivity in a fraction of the cells. Strongest staining was observed in urinary bladder, stomach and heart muscle. Most other tissues showed weak to moderate immunoreactivity.
HPA006028
Strong nuclear and cytoplasmic positivity was observed in heart muscle. In respiratory epithelia and basal cells of prostate gland and squamous epithelia, moderate to strong cytoplasmic and nuclear immunoreactivity was found. Remaining normal tissues were in general negative.
CAB008368
Normal tissues generally showed weak to moderate cytoplasmic positivity. Strong immunoreactivity was observed in heart muscle, cervical glandular cells and subsets of cells in renal glomeruli. Lymphoid tissues and most cells in CNS displayed weak staining or were negative.
The Human Protein Atlas project is funded
