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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:69.4 nTPM
HPA:69.4 nTPM
GTEx:66.9 nTPM
FANTOM5:97.7 Scaled Tags Per Million
Pig:141.5 nTPM
Mouse:225.4 nTPM
Allen mouse:8.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 69.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.9
2219 Male, age 76, both hemispheres 77.6
2411 Female, age 72, unknown 64.6
2586 Male, age 75, left hemisphere 59.6
1827 Male, age 72, unknown 58.2
2666 Male, age 74, left hemisphere 57.1
2019 Male, age 18, unknown 56.7
1870 Female, age 42, unknown 54.0
1833 Male, age 53, unknown 52.6
1830 Male, age 51, unknown 49.7
2828 Female, age 72, unknown 48.9
Dorsal raphe nucleus
nTPM: 59.0
2298 Female, age 72, unknown 64.2
1828 Male, age 53, unknown 64.1
2047 Male, age 72, unknown 62.2
2750 Male, age 76, both hemispheres 59.8
2016 Female, age 72, unknown 44.7
Inferior colliculus
nTPM: 53.2
2097 Female, age 72, unknown 59.6
1890 Male, age 53, unknown 53.1
1848 Female, age 42, unknown 52.8
2849 Male, age 72, unknown 47.2
Median raphe nucleus
nTPM: 61.5
2220 Male, age 76, midline 61.5
Pedunculopontine tegmental nucleus
nTPM: 56.0
2334 Male, age 80, both hemispheres 64.8
1921 Female, age 85, both hemispheres 55.9
2338 Male, age 61, both hemispheres 47.4
Periaquaductal grey, anterior
nTPM: 56.7
2502 Female, age 75, unknown 59.2
1947 Male, age 18, unknown 58.4
1795 Male, age 51, unknown 52.5
Periaquaductal grey, dorsal
nTPM: 46.3
1840 Male, age 53, unknown 51.4
2464 Female, age 72, unknown 48.3
1831 Male, age 72, unknown 44.8
2850 Male, age 76, both hemispheres 40.6
Periaquaductal grey, lateral
nTPM: 42.3
2053 Male, age 18, unknown 43.6
2272 Male, age 74, both hemispheres 43.0
2140 Male, age 76, both hemispheres 40.3
Pretectal area
nTPM: 54.5
1816 Male, age 51, unknown 65.2
2007 Male, age 72, unknown 64.5
1944 Female, age 72, unknown 62.2
1817 Female, age 42, unknown 61.3
1815 Male, age 53, unknown 56.7
2667 Female, age 75, unknown 52.8
2825 Male, age 18, unknown 51.5
2224 Female, age 72, unknown 50.8
2407 Male, age 75, both hemispheres 48.5
2316 Male, age 76, right hemisphere 45.0
2273 Male, age 74, both hemispheres 40.5
Red nucleus
nTPM: 55.6
1821 Female, age 72, unknown 70.0
2584 Male, age 75, left hemisphere 60.1
1954 Female, age 42, unknown 56.5
2227 Male, age 72, unknown 56.5
2725 Female, age 75, unknown 55.3
2769 Male, age 72, unknown 54.9
2588 Male, age 74, left hemisphere 54.4
1904 Male, age 53, unknown 54.3
2785 Male, age 18, unknown 53.3
1865 Male, age 51, unknown 52.4
2503 Female, age 72, unknown 52.2
2823 Male, age 76, right hemisphere 47.2
Substantia nigra
nTPM: 69.4
1916 Female, age 42, unknown 96.8
1851 Male, age 51, unknown 78.5
2241 Male, age 72, unknown 77.8
1941 Male, age 53, unknown 69.2
2409 Female, age 72, unknown 66.6
1889 Female, age 72, unknown 65.5
2699 Male, age 18, unknown 63.6
2583 Male, age 75, right hemisphere 61.0
2665 Male, age 74, both hemispheres 57.7
2590 Female, age 75, unknown 56.8
Superior colliculus
nTPM: 51.0
2668 Female, age 75, unknown 59.4
2087 Female, age 72, unknown 58.2
2261 Male, age 18, unknown 56.0
1796 Male, age 53, unknown 51.9
1839 Male, age 51, unknown 51.3
1895 Male, age 76, right hemisphere 50.6
2664 Male, age 75, both hemispheres 49.6
2587 Male, age 74, left hemisphere 49.5
1913 Female, age 42, unknown 44.2
1995 Male, age 72, unknown 39.8
Ventral tegmental area
nTPM: 64.2
2410 Female, age 72, unknown 76.0
1915 Female, age 42, unknown 72.3
2218 Male, age 76, both hemispheres 68.4
1942 Male, age 51, unknown 59.6
2223 Female, age 72, unknown 56.3
2021 Male, age 53, unknown 52.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 66.9
Samples: 139

Max nTPM: 156.8
Min nTPM: 32.7
Std nTPM: 23.6
Median nTPM: 57.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 156.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 150.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 136.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 136.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 124.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 119.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 114.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 112.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 102.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 102.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 101.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 98.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 98.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 98.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 97.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 96.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 95.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 94.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 93.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 93.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 92.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 91.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 89.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 89.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 88.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 87.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 84.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 83.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 82.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 81.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 79.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 78.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 77.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 76.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 75.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 74.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 73.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 73.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 73.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 72.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 70.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 70.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 70.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 69.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 68.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 68.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 68.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 68.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 68.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 67.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 65.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 65.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 65.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 64.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 64.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 61.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 60.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 60.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 60.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 59.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 58.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 57.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 57.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 57.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 57.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 56.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 56.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 56.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 56.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 55.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 55.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 55.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 55.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 55.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 55.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 54.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 54.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 54.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 54.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 54.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 53.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 53.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 53.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 53.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 53.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 52.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 52.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 52.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 52.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 52.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 51.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 51.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 50.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 50.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 50.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 49.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 48.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 48.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 47.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 47.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 47.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 46.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 46.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 46.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 45.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 45.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 45.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 45.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 45.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 45.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 44.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 44.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 44.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 44.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 43.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 42.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 41.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 41.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 40.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 38.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 37.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 35.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 32.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 97.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 97.7
FF:10158-103A5 76 years, female 97.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 141.5
Pig sample Sample description nTPM
Midbrain
nTPM: 138.5
Samples: 4

Max nTPM: 163.3
Min nTPM: 127.7
Sample A Female 133.5
Sample B Female 127.7
Sample C Male 163.3
Sample D Male 129.4
Periaqueductal gray
nTPM: 102.2
Samples: 3

Max nTPM: 112.2
Min nTPM: 84.7
Sample B Female 109.7
Sample C Male 112.2
Sample D Male 84.7
Substantia nigra
nTPM: 118.1
Samples: 4

Max nTPM: 160.5
Min nTPM: 87.3
Sample A Female 160.5
Sample B Female 95.2
Sample C Male 129.2
Sample D Male 87.3
Superior colliculi
nTPM: 141.5
Samples: 4

Max nTPM: 166.1
Min nTPM: 109.2
Sample A Female 161.8
Sample B Female 109.2
Sample C Male 166.1
Sample D Male 128.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 225.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 225.5
Samples: 4

Max nTPM: 228.8
Min nTPM: 221.7
Sample A Male 223.1
Sample B Male 228.2
Sample C Female 228.8
Sample D Female 221.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.6
69028402 Antisense, RP_050316_01_C04, Mouse strain C57BL/6J (56 days, male) 8.6

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