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TMEM59
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:239.1 nTPM
HPA:239.1 nTPM
FANTOM5:212.2 Scaled Tags Per Million
Pig:173.4 nTPM
Allen mouse:12.4 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 239.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 201.7
2090 Male, age 80, both hemispheres 216.7
2188 Female, age 91, both hemispheres 216.7
2301 Female, age 85, both hemispheres 191.6
1984 Male, age 76, both hemispheres 181.7
Dorsal cochlear nucleus
nTPM: 198.9
2187 Female, age 91, both hemispheres 213.2
2378 Male, age 80, both hemispheres 200.4
2802 Male, age 74, right hemisphere 200.0
2370 Male, age 61, both hemispheres 190.8
2058 Male, age 76, both hemispheres 190.1
Dorsal tegmental nucleus
nTPM: 195.9
2083 Male, age 80, both hemispheres 220.7
2326 Male, age 74, both hemispheres 209.2
1936 Male, age 76, left hemisphere 185.5
2358 Male, age 61, both hemispheres 168.2
Dorsolateral tegmental area
nTPM: 206.0
2751 Female, age 85, both hemispheres 239.2
2654 Male, age 80, both hemispheres 219.0
2337 Male, age 61, both hemispheres 197.7
2360 Male, age 74, both hemispheres 194.8
2141 Male, age 76, both hemispheres 179.5
Kolliker-Fuse nucleus
nTPM: 205.2
2315 Male, age 76, right hemisphere 208.0
2793 Female, age 91, left hemisphere 206.6
2163 Male, age 80, both hemispheres 200.9
Lateral lemniscal nuclei
nTPM: 197.0
2746 Female, age 85, left hemisphere 206.5
2036 Male, age 80, both hemispheres 203.6
2320 Female, age 91, left hemisphere 194.9
2453 Male, age 74, right hemisphere 191.2
2169 Male, age 76, both hemispheres 188.8
Lateral parabrachial nucleus
nTPM: 201.6
2792 Male, age 76, both hemispheres 223.5
2013 Male, age 80, both hemispheres 206.6
2139 Female, age 85, right hemisphere 198.4
2790 Male, age 61, both hemispheres 177.7
Lateral vestibular nucleus
nTPM: 196.3
2311 Male, age 80, both hemispheres 204.5
2184 Male, age 76, both hemispheres 188.1
Locus coeruleus
nTPM: 188.6
2014 Male, age 55, unknown 208.1
2123 Female, age 91, both hemispheres 198.8
1980 Male, age 76, both hemispheres 189.1
2788 Male, age 74, unknown 186.7
2317 Female, age 72, unknown 184.2
2162 Male, age 80, both hemispheres 180.2
2720 Male, age 74, both hemispheres 172.8
Medial olivary nucleus
nTPM: 239.1
1943 Male, age 61, both hemispheres 278.2
1962 Male, age 76, both hemispheres 251.1
2138 Female, age 91, both hemispheres 225.1
2851 Male, age 80, both hemispheres 201.8
Medial parabrachial nucleus
nTPM: 203.9
2170 Female, age 91, both hemispheres 229.3
2463 Female, age 85, right hemisphere 217.5
2854 Male, age 80, both hemispheres 200.3
2786 Male, age 76, both hemispheres 194.0
2156 Male, age 61, both hemispheres 178.6
Medial periolivary nuclei
nTPM: 204.2
2791 Male, age 74, right hemisphere 229.7
2081 Male, age 80, both hemispheres 214.4
2063 Male, age 76, both hemispheres 201.5
2458 Female, age 91, both hemispheres 189.3
2171 Female, age 85, both hemispheres 186.1
Motor facial nucleus
nTPM: 197.7
2365 Male, age 74, right hemisphere 226.3
2126 Male, age 61, both hemispheres 220.1
2062 Male, age 76, both hemispheres 196.0
2795 Female, age 91, both hemispheres 187.8
2697 Female, age 85, both hemispheres 185.6
2327 Male, age 80, both hemispheres 170.3
Motor trigeminal nucleus
nTPM: 191.9
2560 Male, age 74, both hemispheres 206.1
2309 Male, age 76, both hemispheres 194.6
2321 Female, age 91, both hemispheres 187.1
2335 Male, age 61, both hemispheres 187.0
2079 Male, age 80, both hemispheres 184.8
Nuclei of the trapezoid body
nTPM: 190.7
1983 Male, age 76, both hemispheres 199.3
2159 Male, age 61, both hemispheres 197.7
2166 Male, age 80, both hemispheres 191.8
2368 Female, age 91, both hemispheres 183.2
2735 Female, age 85, both hemispheres 181.6
Paramedian reticular nucleus
nTPM: 209.8
2057 Male, age 80, both hemispheres 217.0
2052 Male, age 76, both hemispheres 215.8
2050 Female, age 85, both hemispheres 209.4
2313 Male, age 61, both hemispheres 197.2
Pontine nuclei
nTPM: 211.3
2454 Male, age 74, left hemisphere 260.7
2109 Female, age 72, unknown 229.0
2319 Female, age 91, both hemispheres 216.4
2727 Male, age 61, right hemisphere 208.7
1863 Male, age 55, unknown 202.9
2115 Male, age 80, left hemisphere 194.2
1968 Male, age 76, left hemisphere 192.0
2787 Female, age 85, both hemispheres 186.4
Pontine raphe nucleus
nTPM: 192.1
2122 Female, age 85, midline 193.1
2853 Male, age 76, midline 191.2
Posteroventral cochlear nucleus
nTPM: 213.3
2341 Male, age 80, both hemispheres 236.7
2135 Female, age 91, both hemispheres 233.7
2070 Male, age 76, both hemispheres 203.2
2752 Female, age 85, both hemispheres 196.9
2371 Male, age 61, both hemispheres 195.9
Principal sensory trigeminal nucleus
nTPM: 194.5
2367 Female, age 91, left hemisphere 211.9
2008 Male, age 80, left hemisphere 192.4
2158 Male, age 61, both hemispheres 189.9
2324 Male, age 76, both hemispheres 183.6
Reticular pontine nucleus, caudal
nTPM: 201.3
2559 Male, age 74, both hemispheres 224.8
2092 Male, age 76, both hemispheres 203.3
2457 Female, age 91, both hemispheres 200.2
2332 Male, age 80, right hemisphere 176.9
Reticular pontine nucleus, oral
nTPM: 212.5
2361 Male, age 74, both hemispheres 227.8
1939 Male, age 80, both hemispheres 216.8
2012 Female, age 85, both hemispheres 213.7
2167 Male, age 76, both hemispheres 202.9
2366 Female, age 91, both hemispheres 201.3
Reticulotegmental nucleus
nTPM: 188.0
2452 Male, age 74, both hemispheres 195.0
2333 Male, age 80, both hemispheres 189.8
2322 Female, age 91, both hemispheres 188.4
2325 Male, age 76, both hemispheres 178.9
Spinal trigeminal nucleus, oral
nTPM: 190.8
2164 Male, age 80, both hemispheres 193.4
2737 Female, age 85, both hemispheres 192.6
1978 Male, age 76, both hemispheres 186.5
Subcoeruleus area
nTPM: 197.2
2369 Female, age 85, left hemisphere 244.8
1958 Male, age 80, both hemispheres 197.2
2451 Male, age 74, both hemispheres 184.5
2323 Female, age 91, left hemisphere 180.2
2089 Male, age 76, left hemisphere 179.0
Superior olive
nTPM: 203.9
2364 Male, age 74, right hemisphere 231.6
2020 Male, age 76, both hemispheres 212.8
1875 Female, age 85, both hemispheres 200.1
2329 Male, age 80, right hemisphere 191.0
2561 Female, age 91, both hemispheres 184.1
Superior vestibular nucleus
nTPM: 207.7
2015 Male, age 80, both hemispheres 217.5
2383 Male, age 74, both hemispheres 214.2
2061 Male, age 76, both hemispheres 191.4
Ventral periolivary nuclei
nTPM: 191.0
2023 Male, age 76, both hemispheres 217.3
2165 Male, age 80, both hemispheres 193.7
2130 Female, age 85, both hemispheres 178.8
2794 Female, age 91, left hemisphere 174.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 197.1
2449 Male, age 74, both hemispheres 205.5
2840 Female, age 85, both hemispheres 199.6
2456 Female, age 91, both hemispheres 197.5
2359 Male, age 61, both hemispheres 194.8
1959 Male, age 76, both hemispheres 193.9
2161 Male, age 80, both hemispheres 191.4

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 212.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 201.8
FF:10182-103D2 60 years, female 203.5
FF:10165-103B3 76 years, female 200.0
Pons
Scaled Tags Per Million: 212.2
FF:10033-101E6 18-54 years, mixed 212.2

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 173.4
Pig sample Sample description nTPM
Pons
nTPM: 173.4
Samples: 4

Max nTPM: 187.1
Min nTPM: 154.5
Sample A Female 180.3
Sample B Female 154.5
Sample C Male 187.1
Sample D Male 171.8

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.4
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 12.4
69015793 Antisense, RP_050315_01_G01, Mouse strain C57BL/6J (56 days, male) 12.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.