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RPL22
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  • RPL22
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:250.3 nTPM
HPA:250.3 nTPM
GTEx:426.0 nTPM
FANTOM5:224.2 Scaled Tags Per Million
Pig:0.3 nTPM
Mouse:196.7 nTPM
Allen mouse:3.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 250.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 244.1
1870 Female, age 42, unknown 255.7
2666 Male, age 74, left hemisphere 250.7
2219 Male, age 76, both hemispheres 248.6
2586 Male, age 75, left hemisphere 244.8
1827 Male, age 72, unknown 243.1
1833 Male, age 53, unknown 241.1
2411 Female, age 72, unknown 239.8
1830 Male, age 51, unknown 239.7
2019 Male, age 18, unknown 239.0
2828 Female, age 72, unknown 238.1
Dorsal raphe nucleus
nTPM: 240.2
2016 Female, age 72, unknown 242.3
2298 Female, age 72, unknown 242.0
1828 Male, age 53, unknown 240.3
2750 Male, age 76, both hemispheres 239.2
2047 Male, age 72, unknown 237.1
Inferior colliculus
nTPM: 243.7
2849 Male, age 72, unknown 248.3
1890 Male, age 53, unknown 248.1
1848 Female, age 42, unknown 242.1
2097 Female, age 72, unknown 236.2
Median raphe nucleus
nTPM: 244.4
2220 Male, age 76, midline 244.4
Pedunculopontine tegmental nucleus
nTPM: 250.3
2338 Male, age 61, both hemispheres 261.5
2334 Male, age 80, both hemispheres 252.4
1921 Female, age 85, both hemispheres 236.9
Periaquaductal grey, anterior
nTPM: 239.5
2502 Female, age 75, unknown 243.7
1947 Male, age 18, unknown 238.2
1795 Male, age 51, unknown 236.6
Periaquaductal grey, dorsal
nTPM: 243.5
1840 Male, age 53, unknown 248.3
2850 Male, age 76, both hemispheres 246.6
1831 Male, age 72, unknown 243.9
2464 Female, age 72, unknown 235.1
Periaquaductal grey, lateral
nTPM: 235.5
2053 Male, age 18, unknown 242.1
2140 Male, age 76, both hemispheres 236.1
2272 Male, age 74, both hemispheres 228.3
Pretectal area
nTPM: 239.8
1817 Female, age 42, unknown 244.4
1815 Male, age 53, unknown 243.8
1816 Male, age 51, unknown 242.3
2825 Male, age 18, unknown 242.2
2007 Male, age 72, unknown 241.3
2407 Male, age 75, both hemispheres 240.4
2667 Female, age 75, unknown 239.1
2224 Female, age 72, unknown 239.0
1944 Female, age 72, unknown 238.4
2316 Male, age 76, right hemisphere 237.5
2273 Male, age 74, both hemispheres 229.8
Red nucleus
nTPM: 248.5
2503 Female, age 72, unknown 261.9
1821 Female, age 72, unknown 256.3
2588 Male, age 74, left hemisphere 251.9
1865 Male, age 51, unknown 250.6
1904 Male, age 53, unknown 249.4
2584 Male, age 75, left hemisphere 247.9
2227 Male, age 72, unknown 245.8
1954 Female, age 42, unknown 245.0
2725 Female, age 75, unknown 244.2
2769 Male, age 72, unknown 243.8
2823 Male, age 76, right hemisphere 243.4
2785 Male, age 18, unknown 241.8
Substantia nigra
nTPM: 248.1
2409 Female, age 72, unknown 262.8
2699 Male, age 18, unknown 254.2
2665 Male, age 74, both hemispheres 253.2
1851 Male, age 51, unknown 251.7
2590 Female, age 75, unknown 247.2
1889 Female, age 72, unknown 246.7
2241 Male, age 72, unknown 245.5
1916 Female, age 42, unknown 243.8
1941 Male, age 53, unknown 242.2
2583 Male, age 75, right hemisphere 234.1
Superior colliculus
nTPM: 244.5
1913 Female, age 42, unknown 252.7
2587 Male, age 74, left hemisphere 251.8
1995 Male, age 72, unknown 249.7
1895 Male, age 76, right hemisphere 245.4
2668 Female, age 75, unknown 244.4
1839 Male, age 51, unknown 244.2
2664 Male, age 75, both hemispheres 241.0
2261 Male, age 18, unknown 240.6
1796 Male, age 53, unknown 239.8
2087 Female, age 72, unknown 235.3
Ventral tegmental area
nTPM: 243.9
2223 Female, age 72, unknown 252.7
1915 Female, age 42, unknown 250.7
1942 Male, age 51, unknown 242.5
2021 Male, age 53, unknown 241.2
2218 Male, age 76, both hemispheres 240.1
2410 Female, age 72, unknown 236.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 426.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 426.0
Samples: 139

Max nTPM: 1222.2
Min nTPM: 212.3
Std nTPM: 152.8
Median nTPM: 391.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1222.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1176.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 939.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 751.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 719.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 683.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 666.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 661.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 651.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 649.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 649.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 626.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 600.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 597.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 590.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 587.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 567.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 566.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 563.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 551.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 540.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 531.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 525.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 524.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 519.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 516.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 512.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 508.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 508.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 507.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 504.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 501.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 496.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 489.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 487.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 487.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 482.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 479.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 477.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 474.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 474.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 472.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 468.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 467.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 465.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 461.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 456.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 451.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 451.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 445.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 445.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 440.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 436.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 430.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 430.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 423.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 420.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 420.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 416.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 415.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 412.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 409.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 406.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 406.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 405.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 405.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 402.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 400.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 396.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 391.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 390.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 386.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 384.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 383.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 382.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 378.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 376.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 374.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 373.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 371.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 365.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 364.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 363.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 362.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 362.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 357.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 357.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 357.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 357.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 355.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 348.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 346.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 346.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 346.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 344.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 344.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 341.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 339.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 338.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 336.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 331.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 331.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 330.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 330.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 330.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 329.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 324.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 323.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 321.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 321.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 320.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 320.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 318.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 315.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 313.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 313.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 308.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 296.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 295.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 295.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 294.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 293.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 292.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 291.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 282.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 281.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 274.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 274.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 271.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 270.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 266.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 260.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 252.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 251.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 238.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 226.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 226.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 212.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 212.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 224.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 224.2
FF:10158-103A5 76 years, female 224.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 0.3
Pig sample Sample description nTPM
Midbrain
nTPM: 0.1
Samples: 4

Max nTPM: 0.2
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.2
Sample D Male 0.0
Periaqueductal gray
nTPM: 0.2
Samples: 3

Max nTPM: 0.4
Min nTPM: 0.1
Sample B Female 0.2
Sample C Male 0.4
Sample D Male 0.1
Substantia nigra
nTPM: 0.3
Samples: 4

Max nTPM: 0.4
Min nTPM: 0.1
Sample A Female 0.1
Sample B Female 0.3
Sample C Male 0.2
Sample D Male 0.4
Superior colliculi
nTPM: 0.1
Samples: 4

Max nTPM: 0.1
Min nTPM: 0.0
Sample A Female 0.1
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 196.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 196.7
Samples: 4

Max nTPM: 205.2
Min nTPM: 187.6
Sample A Male 197.9
Sample B Male 205.2
Sample C Female 187.6
Sample D Female 196.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.0
68445143 Antisense, RP_050111_02_H03, Mouse strain C57BL/6J (56 days, male) 3.0

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