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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:111.5 nTPM
HPA:111.5 nTPM
GTEx:83.4 nTPM
FANTOM5:16.7 Scaled Tags Per Million
Pig:16.0 nTPM
Mouse:63.6 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 111.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 98.8
2586 Male, age 75, left hemisphere 116.2
2666 Male, age 74, left hemisphere 103.4
1827 Male, age 72, unknown 101.4
2828 Female, age 72, unknown 101.2
2411 Female, age 72, unknown 99.5
1870 Female, age 42, unknown 97.3
1833 Male, age 53, unknown 93.2
1830 Male, age 51, unknown 92.6
2019 Male, age 18, unknown 92.3
2219 Male, age 76, both hemispheres 90.4
Dorsal raphe nucleus
nTPM: 102.2
2298 Female, age 72, unknown 110.4
2047 Male, age 72, unknown 106.5
1828 Male, age 53, unknown 101.2
2016 Female, age 72, unknown 98.9
2750 Male, age 76, both hemispheres 93.9
Inferior colliculus
nTPM: 96.4
2097 Female, age 72, unknown 100.2
1848 Female, age 42, unknown 96.4
1890 Male, age 53, unknown 96.2
2849 Male, age 72, unknown 93.0
Median raphe nucleus
nTPM: 97.8
2220 Male, age 76, midline 97.8
Pedunculopontine tegmental nucleus
nTPM: 94.4
2334 Male, age 80, both hemispheres 98.6
1921 Female, age 85, both hemispheres 96.5
2338 Male, age 61, both hemispheres 88.1
Periaquaductal grey, anterior
nTPM: 111.5
1947 Male, age 18, unknown 117.0
1795 Male, age 51, unknown 113.4
2502 Female, age 75, unknown 104.0
Periaquaductal grey, dorsal
nTPM: 98.2
1840 Male, age 53, unknown 102.8
2464 Female, age 72, unknown 98.8
1831 Male, age 72, unknown 95.8
2850 Male, age 76, both hemispheres 95.5
Periaquaductal grey, lateral
nTPM: 97.1
2053 Male, age 18, unknown 99.7
2140 Male, age 76, both hemispheres 96.9
2272 Male, age 74, both hemispheres 94.8
Pretectal area
nTPM: 100.3
2007 Male, age 72, unknown 104.5
2825 Male, age 18, unknown 104.5
2224 Female, age 72, unknown 103.1
1816 Male, age 51, unknown 103.0
1817 Female, age 42, unknown 102.0
1815 Male, age 53, unknown 100.4
2667 Female, age 75, unknown 99.8
1944 Female, age 72, unknown 99.2
2273 Male, age 74, both hemispheres 96.8
2407 Male, age 75, both hemispheres 96.0
2316 Male, age 76, right hemisphere 93.7
Red nucleus
nTPM: 93.6
2584 Male, age 75, left hemisphere 96.6
2725 Female, age 75, unknown 95.7
2588 Male, age 74, left hemisphere 95.6
2503 Female, age 72, unknown 95.3
1821 Female, age 72, unknown 94.7
1954 Female, age 42, unknown 94.6
2769 Male, age 72, unknown 93.5
2227 Male, age 72, unknown 92.5
1904 Male, age 53, unknown 92.0
1865 Male, age 51, unknown 91.8
2785 Male, age 18, unknown 91.0
2823 Male, age 76, right hemisphere 89.6
Substantia nigra
nTPM: 98.4
1916 Female, age 42, unknown 102.5
2583 Male, age 75, right hemisphere 101.5
1851 Male, age 51, unknown 101.3
1889 Female, age 72, unknown 99.2
2665 Male, age 74, both hemispheres 98.1
2241 Male, age 72, unknown 97.9
2590 Female, age 75, unknown 97.2
1941 Male, age 53, unknown 97.0
2409 Female, age 72, unknown 96.8
2699 Male, age 18, unknown 92.2
Superior colliculus
nTPM: 99.2
2664 Male, age 75, both hemispheres 108.3
2261 Male, age 18, unknown 105.1
1796 Male, age 53, unknown 103.8
2668 Female, age 75, unknown 103.4
2087 Female, age 72, unknown 98.7
1839 Male, age 51, unknown 95.4
1995 Male, age 72, unknown 95.3
2587 Male, age 74, left hemisphere 95.3
1913 Female, age 42, unknown 94.2
1895 Male, age 76, right hemisphere 92.0
Ventral tegmental area
nTPM: 99.3
1942 Male, age 51, unknown 103.9
2410 Female, age 72, unknown 102.1
1915 Female, age 42, unknown 101.0
2021 Male, age 53, unknown 98.8
2218 Male, age 76, both hemispheres 95.1
2223 Female, age 72, unknown 95.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 83.4
Samples: 139

Max nTPM: 183.5
Min nTPM: 44.6
Std nTPM: 21.0
Median nTPM: 79.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 183.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 167.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 139.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 139.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 119.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 115.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 113.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 112.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 111.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 111.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 108.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 108.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 108.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 107.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 107.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 106.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 104.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 104.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 104.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 103.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 103.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 102.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 102.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 102.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 99.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 98.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 98.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 98.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 98.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 98.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 97.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 96.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 96.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 96.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 96.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 95.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 94.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 93.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 92.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 92.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 92.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 92.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 91.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 89.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 89.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 88.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 88.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 87.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 86.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 86.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 86.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 85.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 85.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 85.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 84.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 84.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 83.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 83.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 83.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 82.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 81.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 80.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 80.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 80.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 80.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 80.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 79.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 79.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 79.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 79.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 78.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 78.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 78.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 78.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 78.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 78.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 77.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 76.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 75.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 75.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 75.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 75.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 75.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 75.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 74.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 73.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 73.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 72.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 72.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 72.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 72.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 71.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 71.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 70.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 70.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 68.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 68.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 68.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 67.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 67.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 67.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 65.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 65.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 64.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 64.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 64.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 64.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 64.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 63.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 62.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 62.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 61.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 60.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 60.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 59.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 59.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 59.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 59.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 58.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 57.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 53.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 52.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 52.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 50.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 50.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 50.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 16.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 16.7
FF:10158-103A5 76 years, female 16.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 16.0
Pig sample Sample description nTPM
Midbrain
nTPM: 14.2
Samples: 4

Max nTPM: 23.2
Min nTPM: 5.8
Sample A Female 5.8
Sample B Female 10.3
Sample C Male 17.4
Sample D Male 23.2
Periaqueductal gray
nTPM: 9.9
Samples: 3

Max nTPM: 11.6
Min nTPM: 8.7
Sample B Female 8.7
Sample C Male 11.6
Sample D Male 9.4
Substantia nigra
nTPM: 11.5
Samples: 4

Max nTPM: 16.5
Min nTPM: 4.1
Sample A Female 16.5
Sample B Female 9.7
Sample C Male 15.6
Sample D Male 4.1
Superior colliculi
nTPM: 16.0
Samples: 4

Max nTPM: 18.6
Min nTPM: 12.7
Sample A Female 18.6
Sample B Female 16.8
Sample C Male 15.9
Sample D Male 12.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 63.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 63.6
Samples: 4

Max nTPM: 68.7
Min nTPM: 58.8
Sample A Male 68.7
Sample B Male 58.8
Sample C Female 59.9
Sample D Female 67.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
77910727 Antisense, RP_070208_04_F08, Mouse strain C57BL/6J (56 days, male) 3.7
583862 Antisense, RP_040831_01_C01, Mouse strain C57BL/6J (56 days, male) 1.1

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