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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.4 nTPM
HPA:155.4 nTPM
GTEx:114.7 nTPM
FANTOM5:33.2 Scaled Tags Per Million
Pig:95.2 nTPM
Mouse:175.6 nTPM
Allen mouse:1.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 147.0
2019 Male, age 18, unknown 157.9
2411 Female, age 72, unknown 153.0
1827 Male, age 72, unknown 148.7
2219 Male, age 76, both hemispheres 148.2
1870 Female, age 42, unknown 148.0
1833 Male, age 53, unknown 145.3
2666 Male, age 74, left hemisphere 144.7
1830 Male, age 51, unknown 143.0
2828 Female, age 72, unknown 141.3
2586 Male, age 75, left hemisphere 139.9
Dorsal raphe nucleus
nTPM: 151.6
2298 Female, age 72, unknown 158.7
1828 Male, age 53, unknown 153.7
2750 Male, age 76, both hemispheres 150.2
2047 Male, age 72, unknown 148.4
2016 Female, age 72, unknown 147.2
Inferior colliculus
nTPM: 149.2
2097 Female, age 72, unknown 156.9
1890 Male, age 53, unknown 154.3
1848 Female, age 42, unknown 144.1
2849 Male, age 72, unknown 141.3
Median raphe nucleus
nTPM: 149.6
2220 Male, age 76, midline 149.6
Pedunculopontine tegmental nucleus
nTPM: 152.3
2334 Male, age 80, both hemispheres 153.4
2338 Male, age 61, both hemispheres 152.1
1921 Female, age 85, both hemispheres 151.4
Periaquaductal grey, anterior
nTPM: 146.5
1947 Male, age 18, unknown 148.0
1795 Male, age 51, unknown 146.4
2502 Female, age 75, unknown 145.1
Periaquaductal grey, dorsal
nTPM: 144.9
2850 Male, age 76, both hemispheres 147.3
2464 Female, age 72, unknown 145.2
1840 Male, age 53, unknown 143.8
1831 Male, age 72, unknown 143.4
Periaquaductal grey, lateral
nTPM: 144.2
2272 Male, age 74, both hemispheres 146.4
2053 Male, age 18, unknown 144.5
2140 Male, age 76, both hemispheres 141.6
Pretectal area
nTPM: 154.4
2667 Female, age 75, unknown 163.9
2007 Male, age 72, unknown 163.1
1816 Male, age 51, unknown 162.1
1817 Female, age 42, unknown 161.3
1944 Female, age 72, unknown 158.1
1815 Male, age 53, unknown 156.8
2224 Female, age 72, unknown 150.8
2273 Male, age 74, both hemispheres 150.8
2316 Male, age 76, right hemisphere 146.4
2825 Male, age 18, unknown 142.7
2407 Male, age 75, both hemispheres 142.2
Red nucleus
nTPM: 151.0
1821 Female, age 72, unknown 169.8
2823 Male, age 76, right hemisphere 155.2
1954 Female, age 42, unknown 154.1
1865 Male, age 51, unknown 152.9
2785 Male, age 18, unknown 150.9
1904 Male, age 53, unknown 150.1
2503 Female, age 72, unknown 149.5
2769 Male, age 72, unknown 149.5
2227 Male, age 72, unknown 148.9
2725 Female, age 75, unknown 146.9
2588 Male, age 74, left hemisphere 143.1
2584 Male, age 75, left hemisphere 140.5
Substantia nigra
nTPM: 155.4
1916 Female, age 42, unknown 166.2
2241 Male, age 72, unknown 165.9
1851 Male, age 51, unknown 159.6
1889 Female, age 72, unknown 159.6
2409 Female, age 72, unknown 158.8
1941 Male, age 53, unknown 154.6
2590 Female, age 75, unknown 150.1
2699 Male, age 18, unknown 150.1
2665 Male, age 74, both hemispheres 146.8
2583 Male, age 75, right hemisphere 142.0
Superior colliculus
nTPM: 147.7
2087 Female, age 72, unknown 154.5
1895 Male, age 76, right hemisphere 151.7
2587 Male, age 74, left hemisphere 151.5
2261 Male, age 18, unknown 149.6
2668 Female, age 75, unknown 148.5
1796 Male, age 53, unknown 146.4
1913 Female, age 42, unknown 145.4
1995 Male, age 72, unknown 144.8
1839 Male, age 51, unknown 144.2
2664 Male, age 75, both hemispheres 140.3
Ventral tegmental area
nTPM: 151.2
1915 Female, age 42, unknown 158.2
2218 Male, age 76, both hemispheres 155.5
2410 Female, age 72, unknown 155.0
2223 Female, age 72, unknown 148.4
1942 Male, age 51, unknown 145.6
2021 Male, age 53, unknown 144.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 114.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 114.7
Samples: 139

Max nTPM: 227.9
Min nTPM: 68.1
Std nTPM: 29.6
Median nTPM: 110.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 227.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 212.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 203.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 194.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 182.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 175.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 170.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 169.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 168.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 160.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 157.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 154.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 153.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 153.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 148.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 148.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 146.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 146.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 146.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 145.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 144.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 144.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 142.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 141.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 139.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 138.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 138.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 137.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 137.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 137.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 133.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 133.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 132.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 130.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 130.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 128.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 127.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 126.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 126.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 126.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 125.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 125.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 125.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 125.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 124.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 123.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 122.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 122.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 122.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 122.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 121.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 121.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 120.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 119.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 119.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 118.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 118.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 117.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 116.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 116.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 115.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 114.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 113.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 113.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 112.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 112.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 111.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 111.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 110.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 110.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 109.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 108.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 108.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 107.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 106.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 105.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 105.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 104.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 103.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 103.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 102.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 101.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 101.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 101.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 100.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 100.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 99.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 99.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 98.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 97.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 96.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 96.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 95.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 95.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 94.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 94.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 94.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 94.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 93.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 93.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 92.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 92.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 92.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 92.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 91.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 91.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 91.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 90.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 90.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 89.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 88.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 88.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 88.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 88.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 87.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 86.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 86.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 86.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 85.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 85.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 84.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 83.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 82.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 82.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 82.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 82.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 81.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 80.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 77.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 75.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 74.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 74.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 72.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 71.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 70.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 68.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 33.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.2
FF:10158-103A5 76 years, female 33.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 95.2
Pig sample Sample description nTPM
Midbrain
nTPM: 91.7
Samples: 4

Max nTPM: 97.8
Min nTPM: 86.2
Sample A Female 97.8
Sample B Female 92.2
Sample C Male 86.2
Sample D Male 90.6
Periaqueductal gray
nTPM: 75.3
Samples: 3

Max nTPM: 82.6
Min nTPM: 69.2
Sample B Female 74.0
Sample C Male 82.6
Sample D Male 69.2
Substantia nigra
nTPM: 78.2
Samples: 4

Max nTPM: 103.9
Min nTPM: 62.2
Sample A Female 103.9
Sample B Female 62.2
Sample C Male 82.8
Sample D Male 63.7
Superior colliculi
nTPM: 95.3
Samples: 4

Max nTPM: 106.8
Min nTPM: 68.7
Sample A Female 106.4
Sample B Female 68.7
Sample C Male 106.8
Sample D Male 99.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 175.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 175.6
Samples: 4

Max nTPM: 183.1
Min nTPM: 167.6
Sample A Male 167.6
Sample B Male 183.1
Sample C Female 168.9
Sample D Female 182.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.0
70473927 Antisense, RP_050614_04_E11, Mouse strain C57BL/6J (56 days, male) 1.0

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