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MXI1
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  • MXI1
PROTEIN STRUCTURE
ANTIBODIES
AND
VALIDATION
Protein structures
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

MXI1
Synonyms bHLHc11, MAD2, MXD2, MXI
Gene descriptioni

Full gene name according to HGNC.

MAX interactor 1, dimerization protein
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Read more
Cancer-related genes
Disease related genes
Transcription factors
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Read more
Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 10
Cytoband q25.2
Chromosome location (bp) 110207605 - 110287365
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

26
Ensembl ENSG00000119950 (version 103.38)
Entrez gene 4601
HGNC HGNC:7534
UniProt P50539 (UniProt - Evidence at protein level)
neXtProt NX_P50539
Antibodypedia MXI1 antibodies


PROTEIN STRUCTUREi

The Structure section provides predicted structures from the Alphafold protein structure database and available experimental structures from Protein Data Bank (PDB).

In the Structure drop-down menu all experimental structures from PDB are available for selection and display. The structures are displayed using the NGL Viewer and can be zoomed-in and rotated either manually or by checking the Autorotate box. The Color scheme can be selected to show the residue index, chain name or confidence score (as B-factors and pLDDT score for experimental and predicted structures, respectively). The positions for available antigen sequences in the structure are shown if Antigens is turned to ON, and the Variants slider can be used to show the positions of clinical and population variants.https://github.com/nglviewer/ngl

Read more

Predicted


Description: Structure prediction from Alphafold project. Structure version 2

# Chains: 1      # Clinical variants: 2      # Population variants: 109

Antigens:

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On

Variants:

Off
Clinical
Population

Color scheme:

Confidence
Residue index
Chain name

Autorotate:

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On



PROTEIN BROWSERi

The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The tabs at the top of the protein view section can be used to switch between the different splice variants to which an antigen has been mapped.

At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.

Below the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues (HsID 50). The region with the lowest possible identity is always selected for antigen design, with a maximum identity of 60% allowed for designing a single-target antigen (read more).

The curve in blue displays the predicted antigenicity i.e. the tendency for different regions of the protein to generate an immune response, with peak regions being predicted to be more antigenic.The curve shows average values based on a sliding window approach using an in-house propensity scale. (read more).

If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius (turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.

Low complexity regions are shown in yellow and InterPro regions in green. Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed (read more), and at the bottom of the protein view is the protein scale.
«
MXI1-201
MXI1-202
MXI1-203
MXI1-204
MXI1-205
MXI1-206
MXI1-207
MXI1-211
MXI1-212
MXI1-214
MXI1-215
MXI1-217
MXI1-218
MXI1-220
MXI1-221
MXI1-224
MXI1-225
MXI1-226
MXI1-228
MXI1-229
MXI1-230
MXI1-231
MXI1-232
MXI1-235
MXI1-236
MXI1-237
»


PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant UniProt Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
MXI1-201
ENSP00000239007
ENST00000239007
P50539 [Direct mapping]
Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
228 aa
26.1 kDa
No 0
MXI1-202
ENSP00000331152
ENST00000332674
P50539 [Direct mapping]
Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
295 aa
32.8 kDa
No 0
MXI1-203
ENSP00000354606
ENST00000361248
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3X5 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
182 aa
20.6 kDa
No 0
MXI1-204
ENSP00000358625
ENST00000369612
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-205
ENSP00000376842
ENST00000393134
B1ANN8 [Direct mapping]
Max-interacting protein 1; cDNA FLJ61042, highly similar to MAX-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0046983 [protein dimerization activity]
Show all
218 aa
24.9 kDa
No 0
MXI1-206
ENSP00000407711
ENST00000442296
F6WCI9 [Direct mapping]
Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046983 [protein dimerization activity]
Show all
118 aa
13.8 kDa
No 0
MXI1-207
ENSP00000398981
ENST00000453116
F6U3F6 [Direct mapping]
Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0046983 [protein dimerization activity]
Show all
226 aa
25.3 kDa
No 0
MXI1-211
ENSP00000498900
ENST00000650644
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-212
ENSP00000499158
ENST00000650696
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-214
ENSP00000498390
ENST00000650810
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-215
ENSP00000498547
ENST00000650843
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-217
ENSP00000499161
ENST00000650952
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-218
ENSP00000498396
ENST00000651004
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-220
ENSP00000498951
ENST00000651112
A0A494C1C1 [Direct mapping]
Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0046983 [protein dimerization activity]
Show all
116 aa
13.6 kDa
No 0
MXI1-221
ENSP00000498764
ENST00000651167
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-224
ENSP00000499128
ENST00000651467
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-225
ENSP00000498536
ENST00000651495
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-226
ENSP00000498873
ENST00000651516
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-228
ENSP00000498554
ENST00000651613
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-229
ENSP00000498472
ENST00000651811
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-230
ENSP00000498238
ENST00000651848
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-231
ENSP00000498306
ENST00000651866
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-232
ENSP00000498928
ENST00000652028
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-235
ENSP00000499087
ENST00000652463
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-236
ENSP00000498573
ENST00000652506
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3Y0 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-237
ENSP00000498971
ENST00000652604
P50539 [Direct mapping]
Max-interacting protein 1
A0A0S2Z3X5 [Target identity:100%; Query identity:100%]
MAX interactor 1 isoform 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
182 aa
20.6 kDa
No 0

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