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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 138.4
Min nTPM: 62.3
Std nTPM: 14.9
Median nTPM:
229_1
69 years, female
138.4
375_1
74 years, female
136.4
142_1
61 years, female
133.5
316_1
62 years, male
131.1
153_1
70 years, female
128.5
404_1
82 years, female
128.5
172_1
72 years, female
127.5
413_1
59 years, female
126.5
115_1
83 years, male
126.4
506_1
65 years, male
126.2
145_1
84 years, male
124.2
2_1
77 years, female
124.0
386_1
76 years, male
122.5
18_1
88 years, male
122.3
120_1
70 years, female
122.3
266_1
85 years, male
122.3
243_1
75 years, male
122.0
396_1
62 years, male
121.8
162_1
79 years, female
120.7
4_1
88 years, female
120.2
43_1
64 years, female
120.0
352_1
62 years, male
119.9
324_1
76 years, male
118.9
237_1
82 years, male
118.7
319_1
81 years, male
118.4
81_1
67 years, male
117.8
335_1
73 years, female
117.8
9_1
66 years, female
117.5
17_1
71 years, male
116.6
6_1
73 years, female
116.5
377_1
82 years, female
116.3
286_1
68 years, female
115.9
126_1
63 years, male
115.5
35_1
74 years, female
114.7
246_1
77 years, male
113.3
139_1
64 years, female
113.0
265_1
87 years, male
112.3
313_1
79 years, female
112.3
177_1
74 years, male
112.1
321_1
62 years, female
111.8
501_1
88 years, male
111.6
322_1
76 years, male
111.3
480_1
63 years, male
110.7
425_1
59 years, female
110.3
468_1
89 years, male
110.2
405_1
91 years, male
110.0
447_1
81 years, male
109.7
379_1
60 years, male
108.6
189_1
76 years, male
108.1
347_1
72 years, male
108.0
117_1
61 years, male
107.9
119_1
70 years, female
107.4
452_1
88 years, female
107.3
406_1
79 years, male
105.5
32_1
67 years, male
105.2
217_1
76 years, male
104.7
42_1
85 years, male
104.6
99_1
64 years, male
104.1
318_1
68 years, male
103.7
348_1
84 years, male
103.5
376_1
75 years, female
103.5
163_1
78 years, male
102.7
109_1
81 years, female
102.2
292_1
71 years, male
101.7
264_1
73 years, female
101.3
517_1
88 years, male
101.2
355_1
70 years, female
100.8
350_1
84 years, female
100.7
251_1
78 years, male
100.0
356_1
87 years, female
99.9
254_1
77 years, female
99.7
466_1
57 years, female
99.7
518_1
75 years, female
99.3
354_1
81 years, female
98.9
415_1
77 years, female
98.8
320_1
89 years, female
98.6
414_1
84 years, female
98.1
490_1
67 years, female
98.1
149_1
88 years, male
97.8
288_1
66 years, female
97.0
295_1
61 years, female
96.9
349_1
83 years, male
96.8
173_1
67 years, male
96.6
293_1
68 years, female
96.3
499_1
55 years, female
94.8
526_1
61 years, male
94.6
353_1
82 years, female
93.9
291_1
76 years, male
92.5
137_1
83 years, male
91.6
311_1
78 years, male
91.4
315_1
62 years, female
89.4
314_1
67 years, male
86.2
503_1
68 years, male
85.3
89_1
63 years, male
85.2
351_1
91 years, male
84.7
394_1
75 years, female
84.7
384_1
83 years, male
84.3
491_1
89 years, female
82.2
218_1
71 years, female
82.1
41_1
94 years, female
81.2
317_1
60 years, male
81.2
389_1
86 years, female
77.1
307_1
66 years, female
76.7
308_1
70 years, female
68.8
495_1
57 years, female
62.3
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
