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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA015006
Most normal tissues displayed moderate to strong cytoplasmic immunoreactivity. Cells in cerebellum, pneumocytes and cardiac myocytes were negative.
HPA029040
Most normal tissues displayed moderate to strong cytoplasmic positivity, often seen with a granular pattern. Fallopian tube exhibited additional membranous staining. Strong cytoplasmic and/or nuclear membranous staining was observed in subset of neuronal cells and Purkinje cells.
HPA029041
Most normal tissues showed weak to moderate cytoplasmic positivity. Renal tubules, adrenal gland and seminal vesicles displayed strong immunoreactivity. Soft tissues, glial cells, respiratory epithelia, renal glomeruli, bile ducts, stromal cells in uterus and smooth muscle cells were negative.
HPA050052
Normal tissues displayed moderate to strong cytoplasmic staining with additional membranous positivity in few tissues. Hematopoietic cells, decidual cells, prostate and smooth muscle cells were weakly stained or negative.