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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:117.4 nTPM
HPA:117.4 nTPM
GTEx:69.4 nTPM
FANTOM5:131.2 Scaled Tags Per Million
Pig:49.9 nTPM
Mouse:95.5 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 117.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 106.5
2828 Female, age 72, unknown 109.4
2411 Female, age 72, unknown 108.8
1870 Female, age 42, unknown 107.0
2666 Male, age 74, left hemisphere 106.8
2019 Male, age 18, unknown 105.8
2219 Male, age 76, both hemispheres 105.8
1830 Male, age 51, unknown 105.6
1833 Male, age 53, unknown 105.5
2586 Male, age 75, left hemisphere 105.2
1827 Male, age 72, unknown 105.0
Dorsal raphe nucleus
nTPM: 113.7
2298 Female, age 72, unknown 118.6
2047 Male, age 72, unknown 116.0
1828 Male, age 53, unknown 113.0
2016 Female, age 72, unknown 112.1
2750 Male, age 76, both hemispheres 108.8
Inferior colliculus
nTPM: 111.2
2097 Female, age 72, unknown 115.9
1848 Female, age 42, unknown 111.4
1890 Male, age 53, unknown 110.2
2849 Male, age 72, unknown 107.3
Median raphe nucleus
nTPM: 114.2
2220 Male, age 76, midline 114.2
Pedunculopontine tegmental nucleus
nTPM: 111.5
2334 Male, age 80, both hemispheres 115.4
2338 Male, age 61, both hemispheres 110.5
1921 Female, age 85, both hemispheres 108.7
Periaquaductal grey, anterior
nTPM: 108.2
1795 Male, age 51, unknown 109.9
2502 Female, age 75, unknown 108.6
1947 Male, age 18, unknown 106.2
Periaquaductal grey, dorsal
nTPM: 109.9
2850 Male, age 76, both hemispheres 117.7
1840 Male, age 53, unknown 108.0
2464 Female, age 72, unknown 107.7
1831 Male, age 72, unknown 106.2
Periaquaductal grey, lateral
nTPM: 112.3
2272 Male, age 74, both hemispheres 118.1
2140 Male, age 76, both hemispheres 110.2
2053 Male, age 18, unknown 108.7
Pretectal area
nTPM: 108.9
2667 Female, age 75, unknown 118.3
2273 Male, age 74, both hemispheres 116.6
1944 Female, age 72, unknown 110.6
2825 Male, age 18, unknown 109.3
1816 Male, age 51, unknown 109.2
2224 Female, age 72, unknown 108.9
1817 Female, age 42, unknown 108.4
2007 Male, age 72, unknown 105.9
1815 Male, age 53, unknown 105.5
2316 Male, age 76, right hemisphere 103.3
2407 Male, age 75, both hemispheres 101.7
Red nucleus
nTPM: 111.4
1954 Female, age 42, unknown 118.9
1821 Female, age 72, unknown 115.5
2725 Female, age 75, unknown 115.5
2823 Male, age 76, right hemisphere 113.7
2769 Male, age 72, unknown 112.8
2503 Female, age 72, unknown 112.6
2227 Male, age 72, unknown 112.0
1904 Male, age 53, unknown 111.3
1865 Male, age 51, unknown 111.0
2588 Male, age 74, left hemisphere 106.2
2785 Male, age 18, unknown 105.5
2584 Male, age 75, left hemisphere 101.5
Substantia nigra
nTPM: 117.4
1916 Female, age 42, unknown 137.9
1941 Male, age 53, unknown 128.4
2699 Male, age 18, unknown 127.6
2241 Male, age 72, unknown 121.4
1851 Male, age 51, unknown 118.1
1889 Female, age 72, unknown 111.5
2409 Female, age 72, unknown 110.1
2665 Male, age 74, both hemispheres 108.1
2583 Male, age 75, right hemisphere 107.4
2590 Female, age 75, unknown 103.6
Superior colliculus
nTPM: 107.5
2087 Female, age 72, unknown 112.0
2261 Male, age 18, unknown 110.2
1995 Male, age 72, unknown 109.9
2587 Male, age 74, left hemisphere 108.9
1796 Male, age 53, unknown 108.3
1913 Female, age 42, unknown 107.1
2668 Female, age 75, unknown 106.6
1839 Male, age 51, unknown 105.8
2664 Male, age 75, both hemispheres 103.4
1895 Male, age 76, right hemisphere 102.7
Ventral tegmental area
nTPM: 114.5
1915 Female, age 42, unknown 120.5
2410 Female, age 72, unknown 117.8
2218 Male, age 76, both hemispheres 114.9
1942 Male, age 51, unknown 112.3
2021 Male, age 53, unknown 111.3
2223 Female, age 72, unknown 110.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 69.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 69.4
Samples: 139

Max nTPM: 115.3
Min nTPM: 31.6
Std nTPM: 17.2
Median nTPM: 68.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 115.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 110.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 108.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 107.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 105.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 98.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 96.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 95.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 95.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 94.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 93.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 92.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 91.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 90.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 90.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 90.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 90.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 89.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 88.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 87.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 86.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 86.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 86.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 86.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 86.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 86.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 85.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 84.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 84.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 82.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 82.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 82.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 81.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 80.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 80.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 80.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 80.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 80.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 78.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 78.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 77.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 77.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 77.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 76.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 76.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 76.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 75.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 75.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 75.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 74.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 74.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 74.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 73.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 73.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 73.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 72.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 72.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 72.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 72.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 71.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 71.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 71.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 71.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 69.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 69.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 68.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 68.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 67.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 67.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 67.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 66.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 66.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 66.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 66.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 65.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 65.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 64.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 64.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 63.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 63.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 62.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 62.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 62.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 62.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 61.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 61.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 61.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 60.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 59.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 59.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 58.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 58.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 58.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 57.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 57.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 56.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 56.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 56.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 55.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 55.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 54.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 54.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 54.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 53.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 53.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 53.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 51.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 51.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 51.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 51.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 50.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 48.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 48.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 44.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 43.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 42.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 42.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 41.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 39.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 38.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 38.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 36.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 35.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 34.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 131.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 131.2
FF:10158-103A5 76 years, female 131.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 49.9
Pig sample Sample description nTPM
Midbrain
nTPM: 48.9
Samples: 4

Max nTPM: 63.3
Min nTPM: 41.3
Sample A Female 63.3
Sample B Female 42.2
Sample C Male 48.6
Sample D Male 41.3
Periaqueductal gray
nTPM: 43.0
Samples: 3

Max nTPM: 49.2
Min nTPM: 39.4
Sample B Female 40.4
Sample C Male 49.2
Sample D Male 39.4
Substantia nigra
nTPM: 47.5
Samples: 4

Max nTPM: 58.2
Min nTPM: 42.0
Sample A Female 58.2
Sample B Female 42.0
Sample C Male 47.2
Sample D Male 42.4
Superior colliculi
nTPM: 49.9
Samples: 4

Max nTPM: 59.5
Min nTPM: 44.0
Sample A Female 59.5
Sample B Female 44.0
Sample C Male 49.7
Sample D Male 46.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 95.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 95.4
Samples: 4

Max nTPM: 106.3
Min nTPM: 86.6
Sample A Male 106.3
Sample B Male 86.6
Sample C Female 87.4
Sample D Female 101.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
75079788 Antisense, RP_060412_02_F08, Mouse strain C57BL/6J (56 days, male) 0.7
69133830 Antisense, RP_050321_02_D02, Mouse strain C57BL/6J (56 days, male) 0.6

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