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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 74.9
Min nTPM: 35.9
Std nTPM: 6.5
Median nTPM:
414_1
84 years, female
74.9
413_1
59 years, female
69.1
246_1
77 years, male
64.3
308_1
70 years, female
64.2
501_1
88 years, male
63.9
189_1
76 years, male
63.3
17_1
71 years, male
63.2
313_1
79 years, female
61.2
452_1
88 years, female
60.8
406_1
79 years, male
59.5
415_1
77 years, female
59.4
2_1
77 years, female
59.1
375_1
74 years, female
59.0
377_1
82 years, female
58.9
18_1
88 years, male
58.3
115_1
83 years, male
58.3
153_1
70 years, female
57.9
495_1
57 years, female
57.9
229_1
69 years, female
57.3
386_1
76 years, male
57.1
319_1
81 years, male
56.6
120_1
70 years, female
56.2
142_1
61 years, female
56.1
254_1
77 years, female
56.0
376_1
75 years, female
56.0
265_1
87 years, male
55.9
177_1
74 years, male
55.8
379_1
60 years, male
55.7
396_1
62 years, male
55.5
526_1
61 years, male
55.5
126_1
63 years, male
55.2
315_1
62 years, female
55.2
217_1
76 years, male
54.1
322_1
76 years, male
53.9
405_1
91 years, male
53.8
506_1
65 years, male
53.7
404_1
82 years, female
53.6
394_1
75 years, female
53.5
324_1
76 years, male
53.1
307_1
66 years, female
52.9
288_1
66 years, female
52.8
251_1
78 years, male
52.7
320_1
89 years, female
52.6
321_1
62 years, female
52.6
4_1
88 years, female
52.4
173_1
67 years, male
52.4
266_1
85 years, male
52.2
389_1
86 years, female
52.1
292_1
71 years, male
51.9
425_1
59 years, female
51.8
468_1
89 years, male
51.5
9_1
66 years, female
51.3
518_1
75 years, female
51.3
109_1
81 years, female
51.2
162_1
79 years, female
51.2
352_1
62 years, male
51.2
117_1
61 years, male
50.7
163_1
78 years, male
50.6
384_1
83 years, male
50.6
354_1
81 years, female
50.4
172_1
72 years, female
50.3
466_1
57 years, female
50.3
35_1
74 years, female
50.2
137_1
83 years, male
50.2
32_1
67 years, male
50.1
447_1
81 years, male
50.1
499_1
55 years, female
50.1
145_1
84 years, male
49.9
243_1
75 years, male
49.7
139_1
64 years, female
49.6
351_1
91 years, male
49.5
81_1
67 years, male
49.4
264_1
73 years, female
49.2
295_1
61 years, female
49.1
480_1
63 years, male
49.1
316_1
62 years, male
49.0
119_1
70 years, female
48.4
286_1
68 years, female
48.4
490_1
67 years, female
48.2
6_1
73 years, female
48.1
149_1
88 years, male
47.9
503_1
68 years, male
47.8
491_1
89 years, female
47.2
517_1
88 years, male
47.1
42_1
85 years, male
46.3
335_1
73 years, female
45.2
347_1
72 years, male
45.2
356_1
87 years, female
45.0
41_1
94 years, female
44.9
314_1
67 years, male
44.8
89_1
63 years, male
44.7
349_1
83 years, male
44.2
317_1
60 years, male
44.1
293_1
68 years, female
43.9
348_1
84 years, male
43.4
318_1
68 years, male
42.9
237_1
82 years, male
42.8
291_1
76 years, male
42.1
355_1
70 years, female
41.9
311_1
78 years, male
41.8
353_1
82 years, female
40.7
350_1
84 years, female
40.4
99_1
64 years, male
39.7
43_1
64 years, female
36.9
218_1
71 years, female
35.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
