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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:30.5 nTPM
HPA:30.5 nTPM
GTEx:43.8 nTPM
FANTOM5:79.8 Scaled Tags Per Million
Pig:10.5 nTPM
Mouse:44.2 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 30.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 27.5
1870 Female, age 42, unknown 28.6
2019 Male, age 18, unknown 28.6
1827 Male, age 72, unknown 28.5
2828 Female, age 72, unknown 28.1
2411 Female, age 72, unknown 28.0
1833 Male, age 53, unknown 27.2
2586 Male, age 75, left hemisphere 26.7
2666 Male, age 74, left hemisphere 26.7
1830 Male, age 51, unknown 26.5
2219 Male, age 76, both hemispheres 26.5
Dorsal raphe nucleus
nTPM: 28.7
2298 Female, age 72, unknown 30.1
2750 Male, age 76, both hemispheres 28.9
2047 Male, age 72, unknown 28.4
1828 Male, age 53, unknown 28.2
2016 Female, age 72, unknown 28.0
Inferior colliculus
nTPM: 28.1
2097 Female, age 72, unknown 29.4
1890 Male, age 53, unknown 27.8
2849 Male, age 72, unknown 27.6
1848 Female, age 42, unknown 27.5
Median raphe nucleus
nTPM: 30.5
2220 Male, age 76, midline 30.5
Pedunculopontine tegmental nucleus
nTPM: 28.8
2334 Male, age 80, both hemispheres 29.8
1921 Female, age 85, both hemispheres 29.2
2338 Male, age 61, both hemispheres 27.4
Periaquaductal grey, anterior
nTPM: 27.7
1947 Male, age 18, unknown 28.5
2502 Female, age 75, unknown 27.4
1795 Male, age 51, unknown 27.2
Periaquaductal grey, dorsal
nTPM: 27.5
2850 Male, age 76, both hemispheres 29.3
1831 Male, age 72, unknown 27.4
1840 Male, age 53, unknown 26.8
2464 Female, age 72, unknown 26.6
Periaquaductal grey, lateral
nTPM: 27.8
2140 Male, age 76, both hemispheres 28.5
2272 Male, age 74, both hemispheres 28.5
2053 Male, age 18, unknown 26.4
Pretectal area
nTPM: 28.2
2007 Male, age 72, unknown 30.0
1815 Male, age 53, unknown 29.6
1816 Male, age 51, unknown 29.0
1817 Female, age 42, unknown 28.7
1944 Female, age 72, unknown 28.6
2224 Female, age 72, unknown 28.6
2825 Male, age 18, unknown 27.9
2667 Female, age 75, unknown 27.6
2316 Male, age 76, right hemisphere 27.3
2273 Male, age 74, both hemispheres 26.8
2407 Male, age 75, both hemispheres 26.0
Red nucleus
nTPM: 28.2
1821 Female, age 72, unknown 29.6
2725 Female, age 75, unknown 29.4
2584 Male, age 75, left hemisphere 29.3
1954 Female, age 42, unknown 29.0
2823 Male, age 76, right hemisphere 28.9
1865 Male, age 51, unknown 28.2
1904 Male, age 53, unknown 27.6
2588 Male, age 74, left hemisphere 27.6
2503 Female, age 72, unknown 27.5
2785 Male, age 18, unknown 27.4
2227 Male, age 72, unknown 27.1
2769 Male, age 72, unknown 26.4
Substantia nigra
nTPM: 28.7
1916 Female, age 42, unknown 32.2
1851 Male, age 51, unknown 30.2
1889 Female, age 72, unknown 30.2
1941 Male, age 53, unknown 29.7
2241 Male, age 72, unknown 29.5
2699 Male, age 18, unknown 28.6
2665 Male, age 74, both hemispheres 28.3
2590 Female, age 75, unknown 27.2
2583 Male, age 75, right hemisphere 26.3
2409 Female, age 72, unknown 24.3
Superior colliculus
nTPM: 27.2
2087 Female, age 72, unknown 28.5
2668 Female, age 75, unknown 27.8
2261 Male, age 18, unknown 27.5
2587 Male, age 74, left hemisphere 27.5
1913 Female, age 42, unknown 27.4
1796 Male, age 53, unknown 27.2
1995 Male, age 72, unknown 27.0
1839 Male, age 51, unknown 26.9
1895 Male, age 76, right hemisphere 26.9
2664 Male, age 75, both hemispheres 25.7
Ventral tegmental area
nTPM: 28.7
2410 Female, age 72, unknown 29.8
1915 Female, age 42, unknown 29.5
2218 Male, age 76, both hemispheres 29.2
1942 Male, age 51, unknown 28.2
2021 Male, age 53, unknown 28.2
2223 Female, age 72, unknown 27.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 43.8
Samples: 139

Max nTPM: 68.6
Min nTPM: 16.4
Std nTPM: 9.7
Median nTPM: 43.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 68.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 68.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 64.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 63.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 62.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 62.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 62.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 61.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 61.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 59.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 59.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 58.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 56.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 56.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 55.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 55.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 54.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 54.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 54.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 53.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 53.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 53.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 53.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 52.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 52.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 52.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 52.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 52.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 52.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 51.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 50.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 50.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 49.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 49.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 48.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 48.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 47.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 47.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 47.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 47.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 47.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 46.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 46.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 46.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 46.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 46.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 46.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 46.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 46.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 45.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 45.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 45.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 45.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 44.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 44.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 44.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 44.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 44.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 44.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 44.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 43.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 43.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 43.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 43.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 43.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 42.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 42.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 42.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 42.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 42.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 42.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 42.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 42.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 42.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 42.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 42.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 41.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 41.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 41.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 41.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 41.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 40.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 40.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 40.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 40.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 40.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 40.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 39.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 39.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 39.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 38.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 38.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 38.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 37.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 37.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 36.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 36.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 36.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 35.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 35.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 35.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 34.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 34.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 34.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 34.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 34.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 34.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 33.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 33.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 32.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 32.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 32.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 30.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 30.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 30.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 30.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 29.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 29.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 29.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 29.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 29.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 27.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 26.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 26.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 24.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 18.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 16.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 79.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 79.8
FF:10158-103A5 76 years, female 79.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 10.5
Pig sample Sample description nTPM
Midbrain
nTPM: 10.2
Samples: 4

Max nTPM: 11.3
Min nTPM: 8.5
Sample A Female 8.5
Sample B Female 9.9
Sample C Male 11.3
Sample D Male 11.2
Periaqueductal gray
nTPM: 8.6
Samples: 3

Max nTPM: 9.1
Min nTPM: 8.0
Sample B Female 8.8
Sample C Male 9.1
Sample D Male 8.0
Substantia nigra
nTPM: 9.4
Samples: 4

Max nTPM: 11.6
Min nTPM: 6.7
Sample A Female 11.6
Sample B Female 8.8
Sample C Male 10.5
Sample D Male 6.7
Superior colliculi
nTPM: 10.5
Samples: 4

Max nTPM: 12.2
Min nTPM: 8.5
Sample A Female 11.3
Sample B Female 8.5
Sample C Male 12.2
Sample D Male 10.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 44.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 44.3
Samples: 4

Max nTPM: 48.9
Min nTPM: 42.2
Sample A Male 43.4
Sample B Male 42.2
Sample C Female 48.9
Sample D Female 42.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
68924431 Antisense, RP_050303_02_D01, Mouse strain C57BL/6J (56 days, male) 0.5

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